|Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti‐tumour activity|
CM Shipman, MJ Rogers, JF Apperley, RGG Russell, PI Croucher
British journal of haematology 98 (3), 665-672, 1997
|Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma|
PI Croucher, CM Shipman, J Lippitt, M Perry, K Asosingh, A Hijzen, ...
Blood, The Journal of the American Society of Hematology 98 (13), 3534-3540, 2001
|The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel|
SP Jagdev, RE Coleman, CM Shipman, A Rostami-H, PI Croucher
British journal of cancer 84 (8), 1126-1134, 2001
|The pharmacology of bisphosphonates and new insights into their mechanisms of action|
RGG Russell, MJ Rogers, JC Frith, SP Luckman, FP Coxon, HL Benford, ...
Journal of Bone and Mineral Research 14 (S2), 53-65, 1999
|Zoledronic acid treatment of 5T2MM‐bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and …|
PI Croucher, H De Raeve, MJ Perry, A Hijzen, CM Shipman, J Lippitt, ...
Journal of Bone and Mineral Research 18 (3), 482-492, 2003
|The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway|
CM Shipman, PI Croucher, R Graham, G Russell, MH Helfrich, MJ Rogers
Cancer research 58 (23), 5294, 1998
|Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand and can function as a paracrine survival factor for human …|
CM Shipman, PI Croucher
Cancer research 63 (5), 912, 2003
|Recombinant osteoprotegerin decreases tumor burden and increases survival in a murine model of multiple myeloma|
K Vanderkerken, E De Leenheer, C Shipman, K Asosingh, A Willems, ...
Cancer research 63 (2), 287, 2003
|The pathogenesis of the bone disease of multiple myeloma|
CM Edwards, J Zhuang, GR Mundy
Bone 42 (6), 1007-1013, 2008
|Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo|
CM Edwards, JR Edwards, ST Lwin, J Esparza, BO Oyajobi, B McCluskey, ...
Blood, The Journal of the American Society of Hematology 111 (5), 2833-2842, 2008
|Eph receptors and ephrin signaling pathways: a role in bone homeostasis|
CM Edwards, GR Mundy
International journal of medical sciences 5 (5), 263, 2008
|Role of osteoprotegerin (OPG) in cancer|
I Holen, CM Shipman
Clinical science 110 (3), 279-291, 2006
|A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease|
BP Ayati, CM Edwards, GF Webb, JP Wikswo
Biology direct 5 (1), 1-17, 2010
|Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease.|
JA Fowler, ST Lwin, MT Drake, JR Edwards, RA Kyle, GR Mundy, ...
|Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer|
SR Rao, AE Snaith, D Marino, X Cheng, ST Lwin, IR Orriss, FC Hamdy, ...
British journal of cancer 116 (2), 227-236, 2017
|Osteoclasts in Multiple Myeloma Are Derived from Gr-1+ CD11b+ Myeloid-Derived Suppressor Cells|
J Zhuang, J Zhang, ST Lwin, JR Edwards, CM Edwards, GR Mundy, ...
PloS one 7 (11), e48871, 2012
|LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis|
JR Edwards, SG Sun, R Locklin, CM Shipman, IE Adamopoulos, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2006
|Metformin and prostate cancer: a new role for an old drug|
J Whitburn, CM Edwards, P Sooriakumaran
Current urology reports 18 (6), 1-7, 2017
|Contributions of the host microenvironment to cancer-induced bone disease|
SWZ Olechnowicz, CM Edwards
Cancer research 74 (6), 1625-1631, 2014
|Bone marrow stromal cells create a permissive microenvironment for myeloma development: a new stromal role for Wnt inhibitor Dkk1|
JA Fowler, GR Mundy, ST Lwin, CM Edwards
Cancer Research, 2012