Claire Edwards
Claire Edwards
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Cited by
Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti‐tumour activity
CM Shipman, MJ Rogers, JF Apperley, RGG Russell, PI Croucher
British journal of haematology 98 (3), 665-672, 1997
Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma
PI Croucher, CM Shipman, J Lippitt, M Perry, K Asosingh, A Hijzen, ...
Blood, The Journal of the American Society of Hematology 98 (13), 3534-3540, 2001
The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel
SP Jagdev, RE Coleman, CM Shipman, A Rostami-H, PI Croucher
British journal of cancer 84 (8), 1126-1134, 2001
The pharmacology of bisphosphonates and new insights into their mechanisms of action
RGG Russell, MJ Rogers, JC Frith, SP Luckman, FP Coxon, HL Benford, ...
Journal of Bone and Mineral Research 14 (S2), 53-65, 1999
Zoledronic acid treatment of 5T2MM‐bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and …
PI Croucher, H De Raeve, MJ Perry, A Hijzen, CM Shipman, J Lippitt, ...
Journal of Bone and Mineral Research 18 (3), 482-492, 2003
The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway
CM Shipman, PI Croucher, R Graham, G Russell, MH Helfrich, MJ Rogers
Cancer research 58 (23), 5294, 1998
Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand and can function as a paracrine survival factor for human …
CM Shipman, PI Croucher
Cancer research 63 (5), 912, 2003
Recombinant osteoprotegerin decreases tumor burden and increases survival in a murine model of multiple myeloma
K Vanderkerken, E De Leenheer, C Shipman, K Asosingh, A Willems, ...
Cancer research 63 (2), 287, 2003
The pathogenesis of the bone disease of multiple myeloma
CM Edwards, J Zhuang, GR Mundy
Bone 42 (6), 1007-1013, 2008
Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo
CM Edwards, JR Edwards, ST Lwin, J Esparza, BO Oyajobi, B McCluskey, ...
Blood, The Journal of the American Society of Hematology 111 (5), 2833-2842, 2008
Eph receptors and ephrin signaling pathways: a role in bone homeostasis
CM Edwards, GR Mundy
International journal of medical sciences 5 (5), 263, 2008
Role of osteoprotegerin (OPG) in cancer
I Holen, CM Shipman
Clinical science 110 (3), 279-291, 2006
A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease
BP Ayati, CM Edwards, GF Webb, JP Wikswo
Biology direct 5 (1), 1-17, 2010
Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease.
JA Fowler, ST Lwin, MT Drake, JR Edwards, RA Kyle, GR Mundy, ...
Blood, 2011
Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer
SR Rao, AE Snaith, D Marino, X Cheng, ST Lwin, IR Orriss, FC Hamdy, ...
British journal of cancer 116 (2), 227-236, 2017
Osteoclasts in Multiple Myeloma Are Derived from Gr-1+ CD11b+ Myeloid-Derived Suppressor Cells
J Zhuang, J Zhang, ST Lwin, JR Edwards, CM Edwards, GR Mundy, ...
PloS one 7 (11), e48871, 2012
LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis
JR Edwards, SG Sun, R Locklin, CM Shipman, IE Adamopoulos, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2006
Metformin and prostate cancer: a new role for an old drug
J Whitburn, CM Edwards, P Sooriakumaran
Current urology reports 18 (6), 1-7, 2017
Contributions of the host microenvironment to cancer-induced bone disease
SWZ Olechnowicz, CM Edwards
Cancer research 74 (6), 1625-1631, 2014
Bone marrow stromal cells create a permissive microenvironment for myeloma development: a new stromal role for Wnt inhibitor Dkk1
JA Fowler, GR Mundy, ST Lwin, CM Edwards
Cancer Research, 2012
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