Verena Heinrich
Verena Heinrich
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Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions
DG Lupiáñez, K Kraft, V Heinrich, P Krawitz, F Brancati, E Klopocki, ...
Cell 161 (5), 1012-1025, 2015
Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish
A Hruscha, P Krawitz, A Rechenberg, V Heinrich, J Hecht, C Haass, ...
Development 140 (24), 4982-4987, 2013
Formation of new chromatin domains determines pathogenicity of genomic duplications
M Franke, DM Ibrahim, G Andrey, W Schwarzer, V Heinrich, R Schöpflin, ...
Nature 538 (7624), 265-269, 2016
Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog)
AJ Will, G Cova, M Osterwalder, WL Chan, L Wittler, N Brieske, V Heinrich, ...
Nature genetics 49 (10), 1539-1545, 2017
Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chromatin folding
G Andrey, R Schöpflin, I Jerković, V Heinrich, DM Ibrahim, C Paliou, ...
Genome research 27 (2), 223-233, 2017
Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis
BK Kragesteen, M Spielmann, C Paliou, V Heinrich, R Schöpflin, ...
Nature genetics 50 (10), 1463-1473, 2018
Preformed chromatin topology assists transcriptional robustness of Shh during limb development
C Paliou, P Guckelberger, R Schöpflin, V Heinrich, A Esposito, ...
Proceedings of the National Academy of Sciences 116 (25), 12390-12399, 2019
Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations
K Kraft, A Magg, V Heinrich, C Riemenschneider, R Schöpflin, ...
Nature cell biology 21 (3), 305-310, 2019
The allele distribution in next-generation sequencing data sets is accurately described as the result of a stochastic branching process
V Heinrich, J Stange, T Dickhaus, P Imkeller, U Krüger, S Bauer, ...
Nucleic acids research 40 (6), 2426-2431, 2012
Filtering for compound heterozygous sequence variants in non-consanguineous pedigrees
T Kamphans, P Sabri, N Zhu, V Heinrich, S Mundlos, PN Robinson, ...
PloS one 8 (8), e70151, 2013
Homozygous and Compound-Heterozygous Mutations in TGDS Cause Catel-Manzke Syndrome
N Ehmke, A Caliebe, R Koenig, SG Kant, Z Stark, V Cormier-Daire, ...
The American Journal of Human Genetics 95 (6), 763-770, 2014
Estimating exome genotyping accuracy by comparing to data from large scale sequencing projects
V Heinrich, T Kamphans, J Stange, D Parkhomchuk, J Hecht, T Dickhaus, ...
Genome medicine 5 (7), 1-11, 2013
Screening for single nucleotide variants, small indels and exon deletions with a next‐generation sequencing based gene panel approach for U sher syndrome
PM Krawitz, D Schiska, U Krüger, S Appelt, V Heinrich, D Parkhomchuk, ...
Molecular genetics & genomic medicine 2 (5), 393-401, 2014
Somatic neurofibromatosis type 1 (NF1) inactivation events in cutaneous neurofibromas of a single NF1 patient
D Emmerich, T Zemojtel, J Hecht, P Krawitz, M Spielmann, J Kühnisch, ...
European Journal of Human Genetics 23 (6), 870-873, 2015
Strategische Umweltcontrolling mit Hilfe der Balanced Scorecard
M Fahrbach, V Heinrich, R Pfitzner
UmweltWirtschaftsForum 8 (2), 41-44, 2000
Hi-C identifies complex genomic rearrangements and TAD-shuffling in developmental diseases
US Melo, R Schöpflin, R Acuna-Hidalgo, MA Mensah, B Fischer-Zirnsak, ...
The American Journal of Human Genetics 106 (6), 872-884, 2020
Non-invasive spectroscopic determination of the antioxidative status of gravidae and neonates
H Lademann, B Gerber, DM Olbertz, ME Darvin, L Stauf, K Ueberholz, ...
Skin pharmacology and physiology 28 (4), 189-195, 2015
CRUP: a comprehensive framework to predict condition-specific regulatory units
A Ramisch, V Heinrich, LV Glaser, A Fuchs, X Yang, P Benner, ...
Genome biology 20 (1), 1-23, 2019
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma
K Helmsauer, ME Valieva, S Ali, RC González, R Schöpflin, C Röefzaad, ...
Nature communications 11 (1), 1-12, 2020
A likelihood ratio-based method to predict exact pedigrees for complex families from next-generation sequencing data
V Heinrich, T Kamphans, S Mundlos, PN Robinson, PM Krawitz
Bioinformatics 33 (1), 72-78, 2017
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