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Hans Widmer
Hans Widmer
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β‐Peptides: Synthesis by Arndt‐Eistert homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X‐ray …
D Seebach, M Overhand, FNM Kühnle, B Martinoni, L Oberer, U Hommel, ...
Helvetica Chimica Acta 79 (4), 913-941, 1996
10781996
Probing the helical secondary structure of short‐chain β‐peptides
D Seebach, PE Ciceri, M Overhand, B Jaun, D Rigo, L Oberer, U Hommel, ...
Helvetica chimica acta 79 (8), 2043-2066, 1996
5101996
β2‐ and β3‐Peptides with Proteinaceous Side Chains: Synthesis and solution structures of constitutional isomers, a novel helical secondary structure and the …
D Seebach, S Abele, K Gademann, G Guichard, T Hintermann, B Jaun, ...
Helvetica Chimica Acta 81 (5‐8), 932-982, 1998
5061998
Origin of t 1 and t 2 ridges in 2D NMR spectra and procedures for suppression
G Otting, H Widmer, G Wagner, K Wüthrich
NMR Struct. Biol, 389-395, 1995
3741995
Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy
J Kallen, C Spitzfaden, MGM Zurini, G Wider, H Widmer, K Wüthrich, ...
Nature 353 (6341), 276-279, 1991
3431991
NMR structure of cyclosporin A bound to cyclophilin in aqueous solution
C Weber, G Wider, B Von Freyberg, R Traber, W Braun, H Widmer, ...
Biochemistry 30 (26), 6563-6574, 1991
3251991
‘Mixed’β‐peptides: A unique helical secondary structure in solution. Preliminary communication
D Seebach, K Gademann, JRV Schreiber, JL Matthews, T Hintermann, ...
Helvetica chimica acta 80 (7), 2033-2038, 1997
3031997
Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides
K Johnsson, RK Allemann, H Widmer, SA Benner
Nature 365 (6446), 530-532, 1993
2831993
Structural and biophysical characterization of the EphB4· EphrinB2 protein-protein interaction and receptor specificity
JE Chrencik, A Brooun, ML Kraus, MI Recht, AR Kolatkar, GW Han, ...
Journal of biological chemistry 281 (38), 28185-28192, 2006
1212006
Receptor-induced conformation change of the immunosuppressant cyclosporin A
K Wüthrich, B Von Freyberg, C Weber, G Wider, R Traber, H Widmer, ...
Science 254 (5034), 953-954, 1991
1191991
Simulated two-dimensional NMR cross-peak fine structures for 1H spin systems in polypeptides and polydeoxynucleotides
H Widmer, K Wüthrich
Journal of Magnetic Resonance (1969) 74 (2), 316-336, 1987
1151987
Protein NMR in biomedical research
W Jahnke, H Widmer
Cellular and Molecular Life Sciences CMLS 61, 580-599, 2004
1142004
Cyclosporin A—cyclophilin complex formation A model based on X‐ray and NMR data
C Spitzfaden, HP Weber, W Braun, J Kallen, G Wider, H Widmer, ...
FEBS letters 300 (3), 291-300, 1992
1121992
Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity
JE Chrencik, A Brooun, MI Recht, ML Kraus, M Koolpe, AR Kolatkar, ...
Structure 14 (2), 321-330, 2006
1082006
Conformational studies of d (AAAAATTTTT) 2 using constraints from nuclear Overhauser effects and from quantitative analysis of the cross-peak fine structures in two-dimensional …
B Celda, H Widmer, W Leupin, WJ Chazin, WA Denny, K Wuethrich
Biochemistry 28 (4), 1462-1471, 1989
1011989
Three‐dimensional structure of the neurotoxin ATX Ia from Anemonia sulcata in aqueous solution determined by nuclear magnetic resonance spectroscopy
H Widmer, M Billeter, K Wüthrich
Proteins: Structure, Function, and Bioinformatics 6 (4), 357-371, 1989
971989
The 3D structure of a cyclosporin analogue in water is nearly identical to the cyclophilin-bound cyclosporin conformation
RM Wenger, J France, G Bovermann, L Walliser, A Widmer, H Widmer
FEBS letters 340 (3), 255-259, 1994
891994
Simulation of two-dimensional NMR experiments using numerical density matrix calculations
H Widmer, K Wüthrich
Journal of Magnetic Resonance (1969) 70 (2), 270-279, 1986
831986
Use of a double half-filter in two-dimensional proton NMR studies of receptor-bound cyclosporin
G Wider, C Weber, R Traber, H Widmer, K Wuethrich
Journal of the American Chemical Society 112 (24), 9015-9016, 1990
801990
Determination of the NMR solution structure of the cyclophilin A-cyclosporin A complex
C Spitzfaden, W Braun, G Wider, H Widmer, K Wüthrich
Journal of biomolecular NMR 4, 463-482, 1994
791994
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