α-Synuclein interacts with glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseases TL Yap, JM Gruschus, A Velayati, W Westbroek, E Goldin, N Moaven, ...
Journal of Biological Chemistry, jbc. M111. 237859, 2011
214 2011 Phosphoinositide-dependent activation of the ADP-ribosylation factor GTPase-activating protein ASAP1: evidence for the pleckstrin homology domain functioning as an allosteric site JL Kam, K Miura, TR Jackson, J Gruschus, P Roller, S Stauffer, J Clark, ...
Journal of Biological Chemistry 275 (13), 9653-9663, 2000
149 2000 Observation of a narrow superconducting transition at 6 GHz in crystals of Y DL Rubin, K Green, J Gruschus, J Kirchgessner, D Moffat, H Padamsee, ...
Physical Review B 38 (10), 6538, 1988
125 1988 New Hamiltonian model for long-range electronic superexchange in complex molecular structures JM Gruschus, A Kuki
The Journal of Physical Chemistry 97 (21), 5581-5593, 1993
115 1993 Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity JM Gruschus, DHH Tsao, LH Wang, M Nirenberg, JA Ferretti
Biochemistry 36 (18), 5372-5380, 1997
103 1997 Histone H4 K16Q mutation, an acetylation mimic, causes structural disorder of its N-terminal basic patch in the nucleosome BR Zhou, H Feng, R Ghirlando, H Kato, J Gruschus, Y Bai
Journal of molecular biology 421 (1), 30-37, 2012
96 2012 The Three-dimensional Solution Structure of the NK-2 Homeodomain fromDrosophila DHH Tsao, JM Gruschus, LH Wang, M Nirenberg, JA Ferretti
Journal of molecular biology 251 (2), 297-307, 1995
83 1995 Elongation of helix III of the NK-2 homeodomain upon binding to DNA: a secondary structure study by NMR DHH Tsao, JM Gruschus, LH Wang, M Nirenberg, JA Ferretti
Biochemistry 33 (50), 15053-15060, 1994
82 1994 Autoinhibition of Arf GTPase-activating protein activity by the BAR domain in ASAP1 X Jian, P Brown, P Schuck, JM Gruschus, A Balbo, JE Hinshaw, ...
Journal of biological chemistry 284 (3), 1652-1663, 2009
79 2009 Germ-line mutation of NKX3. 1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function SL Zheng, J Ju, B Chang, E Ortner, J Sun, SD Isaacs, J Sun, KE Wiley, ...
Cancer research 66 (1), 69-77, 2006
64 2006 Structural features of membrane-bound glucocerebrosidase and α-synuclein probed by neutron reflectometry and fluorescence spectroscopy TL Yap, Z Jiang, F Heinrich, JM Gruschus, CM Pfefferkorn, M Barros, ...
Journal of Biological Chemistry 290 (2), 744-754, 2015
60 2015 Modifications to the C‐terminus of Arf1 alter cell functions and protein interactions X Jian, M Cavenagh, JM Gruschus, PA Randazzo, RA Kahn
Traffic 11 (6), 732-742, 2010
59 2010 Molecular basis for cooperative binding of anionic phospholipids to the PH domain of the Arf GAP ASAP1 X Jian, WK Tang, P Zhai, NS Roy, R Luo, JM Gruschus, ME Yohe, ...
Structure 23 (11), 1977-1988, 2015
58 2015 The three-dimensional structure of the vnd/NK-2 homeodomain-DNA complex by NMR spectroscopy JM Gruschus, DHH Tsao, LH Wang, M Nirenberg, JA Ferretti
Journal of molecular biology 289 (3), 529-545, 1999
57 1999 Saposin C protects glucocerebrosidase against α-synuclein inhibition TL Yap, JM Gruschus, A Velayati, E Sidransky, JC Lee
Biochemistry 52 (41), 7161-7163, 2013
56 2013 Site-directed mutations in the vnd/nk-2 homeodomain: basis of variations in structure and sequence-specific DNA binding S Weiler, JM Gruschus, DHH Tsao, L Yu, LH Wang, M Nirenberg, ...
Journal of Biological Chemistry 273 (18), 10994-11000, 1998
53 1998 Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains MM Che, ES Boja, HY Yoon, J Gruschus, H Jaffe, S Stauffer, P Schuck, ...
Cellular signalling 17 (10), 1276-1288, 2005
43 2005 Characterization of the N-terminal tail domain of histone H3 in condensed nucleosome arrays by hydrogen exchange and NMR H Kato, J Gruschus, R Ghirlando, N Tjandra, Y Bai
Journal of the American Chemical Society 131 (42), 15104-15105, 2009
42 2009 A low pKa cysteine at the active site of mouse methionine sulfoxide reductase A JC Lim, JM Gruschus, G Kim, BS Berlett, N Tjandra, RL Levine
Journal of Biological Chemistry 287 (30), 25596-25601, 2012
41 2012 The pleckstrin homology (PH) domain of the Arf exchange factor Brag2 is an allosteric binding site X Jian, JM Gruschus, E Sztul, PA Randazzo
Journal of Biological Chemistry 287 (29), 24273-24283, 2012
41 2012