Dendritic function of tau mediates amyloid-β toxicity in Alzheimer's disease mouse models LM Ittner, YD Ke, F Delerue, M Bi, A Gladbach, J van Eersel, H Wölfing, ... Cell 142 (3), 387-397, 2010 | 2060 | 2010 |
Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models J Van Eersel, YD Ke, X Liu, F Delerue, JJ Kril, J Götz, LM Ittner Proceedings of the National Academy of Sciences 107 (31), 13888-13893, 2010 | 314 | 2010 |
Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice A Ittner, SW Chua, J Bertz, A Volkerling, J Van Der Hoven, A Gladbach, ... Science 354 (6314), 904-908, 2016 | 273 | 2016 |
Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease YD Ke, F Delerue, A Gladbach, J Götz, LM Ittner PloS one 4 (11), e7917, 2009 | 224 | 2009 |
Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS YD Ke, A van Hummel, CH Stevens, A Gladbach, S Ippati, M Bi, WS Lee, ... Acta neuropathologica 130, 661-678, 2015 | 77 | 2015 |
Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia I Pleines, J Woods, S Chappaz, V Kew, N Foad, J Ballester-Beltrán, ... The Journal of clinical investigation 127 (3), 814-829, 2017 | 72 | 2017 |
PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells V Chandrakanthan, A Yeola, JC Kwan, RA Oliver, Q Qiao, YC Kang, ... Proceedings of the National Academy of Sciences 113 (16), E2306-E2315, 2016 | 59 | 2016 |
Dimorphic effects of leptin on the circadian and hypocretinergic systems of mice J Mendoza, C Lopez‐Lopez, FG Revel, K Jeanneau, F Delerue, ... Journal of neuroendocrinology 23 (1), 28-38, 2011 | 56 | 2011 |
Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy G von Jonquieres, ZHT Spencer, BD Rowlands, CB Klugmann, A Bongers, ... Acta neuropathologica 135, 95-113, 2018 | 49 | 2018 |
Generation of a new tau knockout (tau Δex1) line using CRISPR/Cas9 genome editing in mice D Tan, S Yao, A Ittner, J Bertz, YD Ke, LM Ittner, F Delerue Journal of Alzheimer's Disease 62 (2), 571-578, 2018 | 48 | 2018 |
Accelerated aging exacerbates a pre‐existing pathology in a tau transgenic mouse model LG Bodea, HT Evans, A Van der Jeugd, LM Ittner, F Delerue, J Kril, ... Aging Cell 16 (2), 377-386, 2017 | 37 | 2017 |
Reduction of advanced tau-mediated memory deficits by the MAP kinase p38γ A Ittner, PR Asih, ARP Tan, E Prikas, J Bertz, K Stefanoska, Y Lin, ... Acta neuropathologica 140, 279-294, 2020 | 26 | 2020 |
In vivo characterization of the aspartyl-tRNA synthetase DARS: homing in on the leukodystrophy HBSL D Fröhlich, AK Suchowerska, ZHT Spencer, G von Jonquieres, ... Neurobiology of disease 97, 24-35, 2017 | 26 | 2017 |
Differential roles for nicotinic and muscarinic cholinergic receptors in sustained visuo-spatial attention? A study using a 5-arm maze protocol in mice L Leblond, C Beaufort, F Delerue, TP Durkin Behavioural brain research 128 (1), 91-102, 2002 | 26 | 2002 |
Methylation of a CGATA element inhibits binding and regulation by GATA-1 L Yang, Z Chen, ES Stout, F Delerue, LM Ittner, MR Wilkins, KGR Quinlan, ... Nature communications 11 (1), 2560, 2020 | 24 | 2020 |
Inducible, tightly regulated and non-leaky neuronal gene expression in mice F Delerue, M White, LM Ittner Transgenic research 23, 225-233, 2014 | 24 | 2014 |
Generation of genetically modified mice through the microinjection of oocytes F Delerue, LM Ittner JoVE (Journal of Visualized Experiments), e55765, 2017 | 20 | 2017 |
Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer’s disease Y Deng, M Bi, F Delerue, SL Forrest, G Chan, J van der Hoven, ... Acta neuropathologica 144 (4), 637-650, 2022 | 18 | 2022 |
Genome editing in mice using CRISPR/Cas9: achievements and prospects F Delerue, LM Ittner Clon Transgen 4 (2), 2015 | 11 | 2015 |
Treatment of epilepsy using a targeted p38γ kinase gene therapy N Morey, M Przybyla, J van der Hoven, YD Ke, F Delerue, J van Eersel, ... Science Advances 8 (48), eadd2577, 2022 | 9 | 2022 |