| Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia KG Roberts, Y Li, D Payne-Turner, RC Harvey, YL Yang, D Pei, ... New England journal of medicine 371 (11), 1005-1015, 2014 | 1477 | 2014 |
| Novel mutations target distinct subgroups of medulloblastoma G Robinson, M Parker, TA Kranenburg, C Lu, X Chen, L Ding, TN Phoenix, ... Nature 488 (7409), 43-48, 2012 | 917 | 2012 |
| “Inside-out” signaling of sphingosine-1-phosphate: therapeutic targets K Takabe, SW Paugh, S Milstien, S Spiegel Pharmacological reviews 60 (2), 181-195, 2008 | 851 | 2008 |
| Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia KG Roberts, RD Morin, J Zhang, M Hirst, Y Zhao, X Su, SC Chen, ... Cancer cell 22 (2), 153-166, 2012 | 837 | 2012 |
| Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases NC Hait, CA Oskeritzian, SW Paugh, S Milstien, S Spiegel Biochimica et Biophysica Acta (BBA)-Biomembranes 1758 (12), 2016-2026, 2006 | 622 | 2006 |
| Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a “come-and-get-me” signal DR Gude, SE Alvarez, SW Paugh, P Mitra, JD Yu, R Griffiths, SE Barbour, ... The FASEB Journal 22 (8), 2629, 2008 | 447 | 2008 |
| The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2 SW Paugh, SG Payne, SE Barbour, S Milstien, S Spiegel FEBS letters 554 (1-2), 189-193, 2003 | 365 | 2003 |
| A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia SW Paugh, BS Paugh, M Rahmani, D Kapitonov, JA Almenara, T Kordula, ... Blood, The Journal of the American Society of Hematology 112 (4), 1382-1391, 2008 | 314 | 2008 |
| Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia B Diouf, KR Crews, G Lew, D Pei, C Cheng, J Bao, JJ Zheng, W Yang, ... Jama 313 (8), 815-823, 2015 | 290 | 2015 |
| Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells S Sarkar, M Maceyka, NC Hait, SW Paugh, H Sankala, S Milstien, ... FEBS letters 579 (24), 5313-5317, 2005 | 271 | 2005 |
| Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin HM Sankala, NC Hait, SW Paugh, D Shida, S Lépine, LW Elmore, P Dent, ... Cancer research 67 (21), 10466-10474, 2007 | 193 | 2007 |
| NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells SW Paugh, EJ Bonten, D Savic, LB Ramsey, WE Thierfelder, P Gurung, ... Nature genetics 47 (6), 607-614, 2015 | 157 | 2015 |
| Interleukin-1 regulates the expression of sphingosine kinase 1 in glioblastoma cells BS Paugh, L Bryan, SW Paugh, KM Wilczynska, SM Alvarez, SK Singh, ... Journal of Biological Chemistry 284 (6), 3408-3417, 2009 | 124 | 2009 |
| EGF regulates plasminogen activator inhibitor-1 (PAI-1) by a pathway involving c-Src, PKCδ, and sphingosine kinase 1 in glioblastoma cells BS Paugh, SW Paugh, L Bryan, D Kapitonov, KM Wilczynska, ... The FASEB journal: official publication of the Federation of American …, 2008 | 109 | 2008 |
| Sphingosine and its analog, the immunosuppressant 2-amino-2-(2-[4-octylphenyl] ethyl)-1, 3-propanediol, interact with the CB1 cannabinoid receptor SW Paugh, MP Cassidy, H He, S Milstien, LJ Sim-Selley, S Spiegel, ... Molecular pharmacology 70 (1), 41-50, 2006 | 92 | 2006 |
| MicroRNAs form triplexes with double stranded DNA at sequence-specific binding sites; a eukaryotic mechanism via which microRNAs could directly alter gene expression SW Paugh, DR Coss, J Bao, LT Laudermilk, CR Grace, AM Ferreira, ... PLoS computational biology 12 (2), e1004744, 2016 | 76 | 2016 |
| PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity G Stocco, W Yang, KR Crews, WE Thierfelder, G Decorti, M Londero, ... Human molecular genetics 21 (21), 4793-4804, 2012 | 75 | 2012 |
| The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia N Pottier, W Yang, M Assem, JC Panetta, D Pei, SW Paugh, C Cheng, ... JNCI: Journal of the National Cancer Institute 100 (24), 1792-1803, 2008 | 73 | 2008 |
| Loss of TBL1XR1 disrupts glucocorticoid receptor recruitment to chromatin and results in glucocorticoid resistance in a B-lymphoblastic leukemia model CL Jones, T Bhatla, R Blum, J Wang, SW Paugh, X Wen, W Bourgeois, ... Journal of Biological Chemistry 289 (30), 20502-20515, 2014 | 70 | 2014 |
| A genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity SH Chen, W Yang, Y Fan, G Stocco, KR Crews, JJ Yang, SW Paugh, ... Leukemia 25 (1), 66-74, 2011 | 59 | 2011 |
