| An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA M Demaria, N Ohtani, SA Youssef, F Rodier, W Toussaint, JR Mitchell, ... Developmental cell 31 (6), 722-733, 2014 | 1988 | 2014 |
| Cellular senescence promotes adverse effects of chemotherapy and cancer relapse M Demaria, MN O'Leary, J Chang, L Shao, SU Liu, F Alimirah, K Koenig, ... Cancer discovery 7 (2), 165-176, 2017 | 1261 | 2017 |
| Direct evidence for epithelial-mesenchymal transitions in breast cancer AJ Trimboli, K Fukino, A De Bruin, G Wei, L Shen, SM Tanner, N Creasap, ... Cancer research 68 (3), 937-945, 2008 | 492 | 2008 |
| Extra-embryonic function of Rb is essential for embryonic development and viability L Wu, A De Bruin, HI Saavedra, M Starovic, A Trimboli, Y Yang, J Opavska, ... Nature 421 (6926), 942-947, 2003 | 450 | 2003 |
| MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling PA da Costa Martins, K Salic, MM Gladka, AS Armand, S Leptidis, ... Nature cell biology 12 (12), 1220-1227, 2010 | 409 | 2010 |
| A proinflammatory gut microbiota increases systemic inflammation and accelerates atherosclerosis E Brandsma, NJ Kloosterhuis, M Koster, DC Dekker, MJJ Gijbels, ... Circulation research 124 (1), 94-100, 2019 | 330 | 2019 |
| High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice RA van der Heijden, F Sheedfar, MC Morrison, PPH Hommelberg, D Kor, ... Aging (Albany NY) 7 (4), 256, 2015 | 326 | 2015 |
| Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation A De Bruin, B Maiti, L Jakoi, C Timmers, R Buerki, G Leone Journal of Biological Chemistry 278 (43), 42041-42049, 2003 | 318 | 2003 |
| Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice WP Vermeij, MET Dollé, E Reiling, D Jaarsma, C Payan-Gomez, ... Nature 537 (7620), 427-431, 2016 | 313 | 2016 |
| In vivo biocompatibility and biodegradation of 3D-printed porous scaffolds based on a hydroxyl-functionalized poly (ε-caprolactone) H Seyednejad, D Gawlitta, RV Kuiper, A de Bruin, CF van Nostrum, ... Biomaterials 33 (17), 4309-4318, 2012 | 285 | 2012 |
| Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development J Li, C Ran, E Li, F Gordon, G Comstock, H Siddiqui, W Cleghorn, ... Developmental cell 14 (1), 62-75, 2008 | 274 | 2008 |
| Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation B Maiti, J Li, A De Bruin, F Gordon, C Timmers, R Opavsky, K Patil, J Tuttle, ... Journal of Biological Chemistry 280 (18), 18211-18220, 2005 | 260 | 2005 |
| A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris R Caldelari, A de Bruin, D Baumann, MM Suter, C Bierkamp, V Balmer, ... The Journal of cell biology 153 (4), 823-834, 2001 | 230 | 2001 |
| Pemphigus vulgaris identifies plakoglobin as key suppressor of c‐Myc in the skin L Williamson, NA Raess, R Caldelari, A Zakher, A de Bruin, H Posthaus, ... The EMBO journal 25 (14), 3298-3309, 2006 | 206 | 2006 |
| Physiological significance of polyploidization in mammalian cells SK Pandit, B Westendorp, A de Bruin Trends in cell biology 23 (11), 556-566, 2013 | 191 | 2013 |
| E2F8 is essential for polyploidization in mammalian cells SK Pandit, B Westendorp, S Nantasanti, E Van Liere, PCJ Tooten, ... Nature cell biology 14 (11), 1181-1191, 2012 | 172 | 2012 |
| Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice A De Bruin, L Wu, HI Saavedra, P Wilson, Y Yang, TJ Rosol, M Weinstein, ... Proceedings of the National Academy of Sciences 100 (11), 6546-6551, 2003 | 168 | 2003 |
| Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects E Sudria-Lopez, M Koppers, M de Wit, C van der Meer, HJ Westeneng, ... Acta neuropathologica 132, 145-147, 2016 | 157 | 2016 |
| Essential role for survivin in early brain development Y Jiang, A De Bruin, H Caldas, J Fangusaro, J Hayes, EM Conway, ... Journal of Neuroscience 25 (30), 6962-6970, 2005 | 153 | 2005 |
| E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1 BGMW Weijts, WJ Bakker, PWA Cornelissen, KH Liang, FH Schaftenaar, ... The EMBO journal 31 (19), 3871-3884, 2012 | 152 | 2012 |
Bart van de Sluis, PhDProfessor of Molecular Genetics (Department of Pediatrics), University of GroningenVerified email at umcg.nl
