The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors MA Hossain, KJ Rosengren, LM Haugaard-Jonsson, S Zhang, S Layfield, ... Journal of biological chemistry 283 (25), 17287-17297, 2008 | 113 | 2008 |
Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1 F Shabanpoor, M Akhter Hossain, PJ Ryan, A Belgi, S Layfield, M Kocan, ... Journal of medicinal chemistry 55 (4), 1671-1681, 2012 | 93 | 2012 |
Use of a temporary “solubilizing” peptide tag for the Fmoc solid-phase synthesis of human insulin glargine via use of regioselective disulfide bond formation MA Hossain, A Belgi, F Lin, S Zhang, F Shabanpoor, L Chan, C Belyea, ... Bioconjugate chemistry 20 (7), 1390-1396, 2009 | 91 | 2009 |
Synthesis, conformation, and activity of human insulin‐like peptide 5 (INSL5) M Akhter Hossain, RAD Bathgate, CK Kong, F Shabanpoor, S Zhang, ... ChemBioChem 9 (11), 1816-1822, 2008 | 91 | 2008 |
Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3 KJ Rosengren, S Zhang, F Lin, NL Daly, DJ Scott, RA Hughes, ... Journal of biological chemistry 281 (38), 28287-28295, 2006 | 81 | 2006 |
Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL7) that exhibit full biological activity MA Hossain, KJ Rosengren, S Zhang, RAD Bathgate, GW Tregear, ... Organic & Biomolecular Chemistry 7 (8), 1547-1553, 2009 | 74 | 2009 |
Solid-phase synthesis of europium-labeled human INSL3 as a novel probe for the study of ligand− receptor interactions F Shabanpoor, RA Hughes, RAD Bathgate, S Zhang, DB Scanlon, F Lin, ... Bioconjugate chemistry 19 (7), 1456-1463, 2008 | 66 | 2008 |
Defining the LGR8 residues involved in binding insulin-like peptide 3 DJ Scott, TN Wilkinson, S Zhang, T Ferraro, JD Wade, GW Tregear, ... Molecular Endocrinology 21 (7), 1699-1712, 2007 | 64 | 2007 |
An Improved Synthesis of Fmoc-N-methyl-α-amino Acids S Zhang, T Govender, T Norström, PI Arvidsson The Journal of organic chemistry 70 (17), 6918-6920, 2005 | 63 | 2005 |
Peptide‐based leptin receptor antagonists for cancer treatment and appetite regulation L Otvos Jr, I Kovalszky, L Scolaro, A Sztodola, J Olah, M Cassone, ... Peptide Science 96 (2), 117-125, 2011 | 54 | 2011 |
Synthesis and circular dichroism spectroscopic investigations of oligomeric β-peptoids with α-chiral side chains AS Norgren, S Zhang, PI Arvidsson Organic Letters 8 (20), 4533-4536, 2006 | 54 | 2006 |
Structure and function relationship of murine insulin-like peptide 5 (INSL5): free C-terminus is essential for RXFP4 receptor binding and activation A Belgi, MA Hossain, F Shabanpoor, L Chan, S Zhang, RAD Bathgate, ... Biochemistry 50 (39), 8352-8361, 2011 | 53 | 2011 |
Regioselective Disulfide Solid Phase Synthesis, Chemical Characterization and In Vitro Receptor Binding Activity of Equine Relaxin MA Hossain, F Lin, S Zhang, T Ferraro, RA Bathgate, GW Tregear, ... International Journal of Peptide Research and Therapeutics 12, 211-215, 2006 | 53 | 2006 |
Simultaneous post-cysteine (S-Acm) group removal quenching of iodine and isolation of peptide by one step ether precipitation S Zhang, F Lin, MA Hossain, F Shabanpoor, GW Tregear, JD Wade International Journal of Peptide Research and Therapeutics 14, 301-305, 2008 | 52 | 2008 |
Role of the intra-A-chain disulfide bond of insulin-like peptide 3 in binding and activation of its receptor, RXFP2 S Zhang, RA Hughes, RAD Bathgate, F Shabanpoor, MA Hossain, F Lin, ... Peptides 31 (9), 1730-1736, 2010 | 36 | 2010 |
Minimum active structure of insulin-like peptide 5 A Belgi, RAD Bathgate, M Kocan, N Patil, S Zhang, GW Tregear, JD Wade, ... Journal of Medicinal Chemistry 56 (23), 9509-9516, 2013 | 34 | 2013 |
Parallel approach for solution-phase synthesis of 2-quinoxalinol analogues and their inhibition of LPS-induced TNF-α release on mouse macrophages in vitro L Zhang, G Liu, SD Zhang, HZ Yang, L Li, XH Wu, J Yu, BB Kou, S Xu, J Li, ... Journal of Combinatorial Chemistry 6 (3), 431-436, 2004 | 34 | 2004 |
A Novel Immunostimulator, N2-[α-O-Benzyl-N-(acetylmuramyl)-l-alanyl-d- isoglutaminyl]-N6-trans-(m-nitrocinnamoyl)-l-lysine, and Its Adjuvancy on the … HZ Yang, S Xu, XY Liao, SD Zhang, ZL Liang, BH Liu, JY Bai, C Jiang, ... Journal of medicinal chemistry 48 (16), 5112-5122, 2005 | 32 | 2005 |
Solution-phase reductive cyclization of 2-quinoxalinol analogs: Systematic study of parallel synthesis XH Wu, G Liu, J Zhang, ZG Wang, S Xu, SD Zhang, L Zhang, L Wang Molecular diversity 8, 165-174, 2004 | 26 | 2004 |
The Structural and Functional Role of the B‐chain C‐terminal Arginine in the Relaxin‐3 Peptide Antagonist, R3 (BΔ23‐27) R/I5 MA Hossain, RAD Bathgate, KJ Rosengren, F Shabanpoor, S Zhang, ... Chemical biology & drug design 73 (1), 46-52, 2009 | 24 | 2009 |