Sina Nassiri
Sina Nassiri
Principal Bioinformatics Data Scientist & Team Leader at Roche pRED
Verified email at
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Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds
KL Spiller, S Nassiri, CE Witherel, RR Anfang, J Ng, KR Nakazawa, T Yu, ...
Biomaterials 37, 194-207, 2015
Interrogation of the microenvironmental landscape in brain tumors reveals disease-specific alterations of immune cells
F Klemm, RR Maas, RL Bowman, M Kornete, K Soukup, S Nassiri, ...
Cell 181 (7), 1643-1660. e17, 2020
T cell–induced CSF1 promotes melanoma resistance to PD1 blockade
NJ Neubert, M Schmittnaegel, N Bordry, S Nassiri, N Wald, C Martignier, ...
Science Translational Medicine 10 (436), 2018
Transcriptome analysis of IL-10-stimulated (M2c) macrophages by next-generation sequencing
EB Lurier, D Dalton, W Dampier, P Raman, S Nassiri, NM Ferraro, ...
Immunobiology 222 (7), 847-856, 2017
Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes
N Mansouri, GR Willis, A Fernandez-Gonzalez, M Reis, S Nassiri, ...
JCI insight 4 (21), 2019
Relative expression of proinflammatory and antiinflammatory genes reveals differences between healing and nonhealing human chronic diabetic foot ulcers
S Nassiri, I Zakeri, MS Weingarten, KL Spiller
The Journal of investigative dermatology 135 (6), 1700, 2015
Molecular profiling and functional analysis of macrophage-derived tumor extracellular vesicles
C Cianciaruso, T Beltraminelli, F Duval, S Nassiri, R Hamelin, A Mozes, ...
Cell reports 27 (10), 3062-3080. e11, 2019
Temporal and spatial distribution of macrophage phenotype markers in the foreign body response to glutaraldehyde-crosslinked gelatin hydrogels
T Yu, W Wang, S Nassiri, T Kwan, C Dang, W Liu, KL Spiller
Journal of Biomaterials science, Polymer edition 27 (8), 721-742, 2016
Pericytes regulate vascular immune homeostasis in the CNS
O Török, B Schreiner, J Schaffenrath, HC Tsai, U Maheshwari, SA Stifter, ...
Proceedings of the National Academy of Sciences 118 (10), e2016587118, 2021
Circulating CD56bright NK cells inversely correlate with survival of melanoma patients
K de Jonge, A Ebering, S Nassiri, ME Hajjami, H Ouertatani-Sakouhi, ...
Scientific reports 9 (1), 1-10, 2019
Integrin-mediated macrophage adhesion promotes lymphovascular dissemination in breast cancer
R Evans, F Flores-Borja, S Nassiri, E Miranda, K Lawler, A Grigoriadis, ...
Cell reports 27 (7), 1967-1978. e4, 2019
Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice
S Ragusa, B Prat-Luri, A González-Loyola, S Nassiri, ML Squadrito, ...
The Journal of clinical investigation 130 (3), 1199-1216, 2020
Differential stromal reprogramming in benign and malignant naturally occurring canine mammary tumours identifies disease-modulating stromal components
P Amini, S Nassiri, A Malbon, E Markkanen
Scientific reports 10 (1), 1-13, 2020
Next-generation RNA sequencing of FFPE subsections reveals highly conserved stromal reprogramming between canine and human mammary carcinoma
P Amini, S Nassiri, J Ettlin, A Malbon, E Markkanen
Disease models & mechanisms 12 (8), dmm040444, 2019
Endothelial calcineurin signaling restrains metastatic outgrowth by regulating Bmp2
S Hendrikx, S Coso, B Prat-Luri, L Wetterwald, A Sabine, CA Franco, ...
Cell reports 26 (5), 1227-1241. e6, 2019
Overcoming microenvironmental resistance to PD-1 blockade in genetically engineered lung cancer models
A Martinez-Usatorre, E Kadioglu, G Boivin, C Cianciaruso, A Guichard, ...
Science translational medicine 13 (606), eabd1616, 2021
Microglia control small vessel calcification via TREM2
Y Zarb, S Sridhar, S Nassiri, SG Utz, J Schaffenrath, U Maheshwari, ...
Science Advances 7 (9), eabc4898, 2021
Inflammatory B cells correlate with failure to checkpoint blockade in melanoma patients
K de Jonge, L Tillé, J Lourenco, H Maby-El Hajjami, S Nassiri, J Racle, ...
Oncoimmunology 10 (1), 1873585, 2021
CD40 Agonist Restores the Antitumor Efficacy of Anti-PD1 Therapy in Muscle-Invasive Bladder Cancer in an IFN I/II-Mediated MannerCD40+ PD1 Blockade Controls Muscle-Invasive …
MM Leblond, L Tillé, S Nassiri, CB Gilfillan, C Imbratta, M Schmittnaegel, ...
Cancer Immunology Research 8 (9), 1180-1192, 2020
Molecular homology between canine spontaneous oral squamous cell carcinomas and human head-and-neck squamous cell carcinomas reveals disease drivers and therapeutic vulnerabilities
F Guscetti, S Nassiri, E Beebe, IR Brandao, R Graf, E Markkanen
Neoplasia 22 (12), 778-788, 2020
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