| Overcoming EGFR (T790M) and EGFR (C797S) resistance with mutant-selective allosteric inhibitors Y Jia, CH Yun, E Park, D Ercan, M Manuia, J Juarez, C Xu, K Rhee, ... Nature 534 (7605), 129-132, 2016 | 789 | 2016 |
| Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites … R Gum, E Lengyel, J Juarez, JH Chen, H Sato, M Seiki, D Boyd Journal of Biological Chemistry 271 (18), 10672-10680, 1996 | 423 | 1996 |
| Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling JC Juarez, M Manuia, ME Burnett, O Betancourt, B Boivin, DE Shaw, ... Proceedings of the National Academy of Sciences 105 (20), 7147-7152, 2008 | 299 | 2008 |
| Regulation of 92 kDa type IV collagenase expression by the jun aminoterminal kinase-and the extracellular signal-regulated kinase-dependent signaling cascades R Gum, H Wang, E Lengyel, J Juarez, D Boyd Oncogene 14 (12), 1481-1493, 1997 | 289 | 1997 |
| Copper binding by tetrathiomolybdate attenuates angiogenesis and tumor cell proliferation through the inhibition of superoxide dismutase 1 JC Juarez, O Betancourt Jr, SR Pirie-Shepherd, X Guan, ML Price, ... Clinical Cancer Research 12 (16), 4974-4982, 2006 | 178 | 2006 |
| Role and regulation of expression of 92‐kDa type‐IV collagenase (MMP‐9) in 2 invasive squamous‐cell‐carcinoma cell lines of the oral cavity J Juarez, G Clayman, M Nakajima, KK Tanabe, H Saya, GL Nicolson, ... International journal of cancer 55 (1), 10-18, 1993 | 157 | 1993 |
| EGF816 exerts anticancer effects in non–small cell lung cancer by irreversibly and selectively targeting primary and acquired activating mutations in the EGF receptor Y Jia, J Juarez, J Li, M Manuia, MJ Niederst, C Tompkins, N Timple, ... Cancer research 76 (6), 1591-1602, 2016 | 126 | 2016 |
| Histidine-proline-rich glycoprotein has potent antiangiogenic activity mediated through the histidine-proline-rich domain JC Juarez, X Guan, NV Shipulina, ML Plunkett, GC Parry, DE Shaw, ... Cancer research 62 (18), 5344-5350, 2002 | 114 | 2002 |
| Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent … G Lelais, R Epple, TH Marsilje, YO Long, M McNeill, B Chen, W Lu, ... Journal of medicinal chemistry 59 (14), 6671-6689, 2016 | 112 | 2016 |
| Requirement of an upstream AP-1 motif for the constitutive and phorbol ester-inducible expression of the urokinase-type plasminogen activator receptor gene E Lengyel, H Wang, E Stepp, J Juarez, Y Wang, W Doe, CM Pfarr, D Boyd Journal of Biological Chemistry 271 (38), 23176-23184, 1996 | 107 | 1996 |
| Induction of Mr 92,000 Type IV Collagenase Expression in a Squamous Cell Carcinoma Cell Line by Fibroblasts E Lengyel, R Gum, J Juarez, G Clayman, M Seiki, H Sato, D Boyd Cancer research 55 (4), 963-967, 1995 | 97 | 1995 |
| Peptides derived from the histidine-proline domain of the histidine-proline-rich glycoprotein bind to tropomyosin and have antiangiogenic and antitumor activities F Doñate, JC Juarez, X Guan, NV Shipulina, ML Plunkett, Z Tel-Tsur, ... Cancer research 64 (16), 5812-5817, 2004 | 75 | 2004 |
| Effect of PD 098059, a Specific Inhibitor of Mitogen-activated Protein Kinase Kinase, on Urokinase Expression and in Vitro Invasion C Simon, J Juarez, GL Nicolson, D Boyd Cancer research 56 (23), 5369-5374, 1996 | 74 | 1996 |
| Identification of biomarkers for the antiangiogenic and antitumour activity of the superoxide dismutase 1 (SOD1) inhibitor tetrathiomolybdate (ATN-224) F Donate, JC Juarez, ME Burnett, MM Manuia, X Guan, DE Shaw, ... British journal of cancer 98 (4), 776-783, 2008 | 72 | 2008 |
| Stimulation of urokinase-type plasminogen activator receptor expression by PMA requires JNK1-dependent and-independent signaling modules R Gum, J Juarez, H Allgayer, A Mazar, Y Wang, D Boyd Oncogene 17 (2), 213-225, 1998 | 69 | 1998 |
| The antiangiogenic activity of cleaved high molecular weight kininogen is mediated through binding to endothelial cell tropomyosin JC Zhang, F Doñate, X Qi, NP Ziats, JC Juarez, AP Mazar, YP Pang, ... Proceedings of the National Academy of Sciences 99 (19), 12224-12229, 2002 | 68 | 2002 |
| Regulation of urokinase‐type plasminogen activator expression by an ERK1‐dependent signaling pathway in a squamous cell carcinoma cell line E Lengyel, R Gum, E Stepp, J Juarez, H Wang, D Boyd Journal of Cellular Biochemistry 61 (3), 430-443, 1996 | 63 | 1996 |
| Histidine-proline rich glycoprotein (HPRG) binds and transduces anti-angiogenic signals through cell surface tropomyosin on endothelial cells X Guan, JC Juarez, X Qi, NV Shipulina, DE Shaw, WT Morgan, ... Thrombosis and haemostasis 92 (08), 403-412, 2004 | 59 | 2004 |
| Single-chain urokinase alone or complexed to its receptor in tetracycline-induced pleuritis in rabbits S Idell, A Mazar, D Cines, A Kuo, G Parry, S Gawlak, J Juarez, K Koenig, ... American journal of respiratory and critical care medicine 166 (7), 920-926, 2002 | 57 | 2002 |
| Transcriptional activation of the urokinase receptor gene in invasive colon cancer H Wang, J Skibber, J Juarez, D Boyd International journal of cancer 58 (5), 650-657, 1994 | 54 | 1994 |
