| Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden ZR Chalmers, CF Connelly, D Fabrizio, L Gay, SM Ali, R Ennis, A Schrock, ... Genome medicine 9, 1-14, 2017 | 2909 | 2017 |
| Tracking footprints of artificial selection in the dog genome JM Akey, AL Ruhe, DT Akey, AK Wong, CF Connelly, J Madeoy, ... Proceedings of the National Academy of Sciences 107 (3), 1160-1165, 2010 | 375 | 2010 |
| Prevalence of PDL1 amplification and preliminary response to immune checkpoint blockade in solid tumors AM Goodman, D Piccioni, S Kato, A Boichard, HY Wang, G Frampton, ... JAMA oncology 4 (9), 1237-1244, 2018 | 231 | 2018 |
| Comprehensive characterization of RAS mutations in colon and rectal cancers in old and young patients IG Serebriiskii, C Connelly, G Frampton, J Newberg, M Cooke, V Miller, ... Nature communications 10 (1), 3722, 2019 | 171 | 2019 |
| Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast DA Skelly, GE Merrihew, M Riffle, CF Connelly, EO Kerr, M Johansson, ... Genome research 23 (9), 1496-1504, 2013 | 157 | 2013 |
| Comprehensive genomic landscapes in early and later onset colorectal cancer CH Lieu, EA Golemis, IG Serebriiskii, J Newberg, A Hemmerich, ... Clinical Cancer Research 25 (19), 5852-5858, 2019 | 147 | 2019 |
| An ortholog of MIXTA‐like2 controls epidermal cell shape in flowers of Thalictrum VS Di Stilio, C Martin, AF Schulfer, CF Connelly New Phytologist 183 (3), 718-728, 2009 | 74 | 2009 |
| Detection of clonal hematopoiesis of indeterminate potential in clinical sequencing of solid tumor specimens EA Severson, GM Riedlinger, CF Connelly, JA Vergilio, M Goldfinger, ... Blood, The Journal of the American Society of Hematology 131 (22), 2501-2505, 2018 | 70 | 2018 |
| Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1 M Maurano, JM Snyder, C Connelly, J Henao-Mejia, C Sidrauski, ... Immunity 54 (9), 1948-1960. e5, 2021 | 69 | 2021 |
| On the prospects of whole-genome association mapping in Saccharomyces cerevisiae CF Connelly, JM Akey Genetics 191 (4), 1345-1353, 2012 | 61 | 2012 |
| Population Genomic Analysis of ALMS1 in Humans Reveals a Surprisingly Complex Evolutionary History LB Scheinfeldt, S Biswas, J Madeoy, CF Connelly, EE Schadt, JM Akey Molecular biology and evolution 26 (6), 1357-1367, 2009 | 40 | 2009 |
| Highly punctuated patterns of population structure on the X chromosome and implications for African evolutionary history CA Lambert, CF Connelly, J Madeoy, R Qiu, MV Olson, JM Akey The American Journal of Human Genetics 86 (1), 34-44, 2010 | 29 | 2010 |
| Evolution and genetic architecture of chromatin accessibility and function in yeast CF Connelly, J Wakefield, JM Akey PLoS genetics 10 (7), e1004427, 2014 | 27 | 2014 |
| Population genomics of intron splicing in 38 Saccharomyces cerevisiae genome sequences DA Skelly, J Ronald, CF Connelly, JM Akey Genome biology and evolution 1, 466-478, 2009 | 24 | 2009 |
| MA14. 01 Updated dataset assessing tumor mutation burden (TMB) as a biomarker for response to PD-1/PD-L1 targeted therapies in lung cancer (LC) A Schrock, N Sharma, N Peled, J Bufill, G Srkalovic, D Spigel, D Fabrizio, ... Journal of Thoracic Oncology 12 (1), S422, 2017 | 22 | 2017 |
| A synthetic biology approach to probing nucleosome symmetry Y Ichikawa, CF Connelly, A Appleboim, TCR Miller, H Jacobi, NA Abshiru, ... Elife 6, e28836, 2017 | 21 | 2017 |
| Determining patient ancestry based on targeted tumor comprehensive genomic profiling J Newberg, C Connelly, G Frampton Cancer Research 79 (13_Supplement), 1599-1599, 2019 | 18 | 2019 |
| Methods and systems for evaluating tumor mutational burden ZR Chalmers, CF Connelly, D Fabrizio, GM Frampton, P Hegde, ... US Patent App. 16/115,373, 2018 | 18 | 2018 |
| Somatic genome alterations in cancer as compared to inferred patient ancestry CF Connelly, J Carrot-Zhang, PJ Stephens, GM Frampton Cancer Research 78 (13 Supplement), 1227-1227, 2018 | 15 | 2018 |
| Population Genomics and Transcriptional Consequences of Regulatory Motif Variation in Globally Diverse Saccharomyces cerevisiae Strains CF Connelly, DA Skelly, MJ Dunham, JM Akey Molecular biology and evolution 30 (7), 1605-1613, 2013 | 13 | 2013 |
Garrett M FramptonFoundation Medicine Inc.Verified email at foundationmedicine.com
