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Emanuele Carosati
Emanuele Carosati
Department of Chemical and Pharmaceutical Sciences, University of Trieste, Italy
Verified email at units.it
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Cited by
Year
MetaSite: understanding metabolism in human cytochromes from the perspective of the chemist
G Cruciani, E Carosati, B De Boeck, K Ethirajulu, C Mackie, T Howe, ...
Journal of medicinal chemistry 48 (22), 6970-6979, 2005
5322005
Hydrogen bonding interactions of covalently bonded fluorine atoms: from crystallographic data to a new angular function in the GRID force field
E Carosati, S Sciabola, G Cruciani
Journal of medicinal chemistry 47 (21), 5114-5125, 2004
2592004
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields
F Broccatelli, E Carosati, A Neri, M Frosini, L Goracci, TI Oprea, ...
Journal of medicinal chemistry 54 (6), 1740-1751, 2011
1752011
IAP antagonists: promising candidates for cancer therapy
R Mannhold, S Fulda, E Carosati
Drug discovery today 15 (5-6), 210-219, 2010
1512010
1, 4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspectives (part 2): action in other targets and antitargets
E Carosati, P Ioan, M Micucci, F Broccatelli, G Cruciani, BS Zhorov, ...
Current medicinal chemistry 19 (25), 4306-4323, 2012
1362012
FLAP: GRID molecular interaction fields in virtual screening. validation using the DUD data set
S Cross, M Baroni, E Carosati, P Benedetti, S Clementi
Journal of chemical information and modeling 50 (8), 1442-1450, 2010
1132010
1, 4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspectives (part 1): action in ion channels and GPCRs
P Ioan, E Carosati, M Micucci, G Cruciani, F Broccatelli, B S Zhorov, ...
Current medicinal chemistry 18 (32), 4901-4922, 2011
1102011
Pyrazolo[4,3-c][1,2]benzothiazines 5,5-Dioxide: A Promising New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors
S Sabatini, F Gosetto, S Serritella, G Manfroni, O Tabarrini, N Iraci, ...
Journal of Medicinal Chemistry 55 (7), 3568-3572, 2012
992012
Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus
JP Brincat, E Carosati, S Sabatini, G Manfroni, A Fravolini, JL Raygada, ...
Journal of medicinal chemistry 54 (1), 354-365, 2011
832011
Calcium channel antagonists discovered by a multidisciplinary approach
E Carosati, G Cruciani, A Chiarini, R Budriesi, P Ioan, R Spisani, ...
Journal of Medicinal Chemistry 49 (17), 5206-5216, 2006
722006
ADME-Space: a new tool for medicinal chemists to explore ADME properties
G Bocci, E Carosati, P Vayer, A Arrault, S Lozano, G Cruciani
Scientific Reports 7 (1), 6359, 2017
712017
Peptide studies by means of principal properties of amino acids derived from MIF descriptors
G Cruciani, M Baroni, E Carosati, M Clementi, R Valigi, S Clementi
Journal of Chemometrics 18 (3‐4), 146-155, 2004
652004
Comparison of ligand-based and structure-based 3D-QSAR approaches: a case study on (aryl-) bridged 2-aminobenzonitriles inhibiting HIV-1 reverse transcriptase
S Sciabola, E Carosati, M Baroni, R Mannhold
Journal of medicinal chemistry 48 (11), 3756-3767, 2005
602005
Homodimeric enzymes as drug targets
D Cardinale, OMH Salo-Ahen, S Ferrari, G Ponterini, G Cruciani, ...
Current medicinal chemistry 17 (9), 826-846, 2010
542010
Large, chemically diverse dataset of log P measurements for benchmarking studies
S Martel, F Gillerat, E Carosati, D Maiarelli, IV Tetko, R Mannhold, ...
European Journal of Pharmaceutical Sciences 48 (1-2), 21-29, 2013
532013
The flavonoid scaffold as a template for the design of modulators of the vascular Cav1.2 channels
S Saponara, E Carosati, P Mugnai, G Sgaragli, F Fusi
British Journal of Pharmacology 164 (6), 1684-1697, 2011
532011
Virtual screening for novel openers of pancreatic KATP channels
E Carosati, R Mannhold, P Wahl, JB Hansen, T Fremming, I Zamora, ...
Journal of medicinal chemistry 50 (9), 2117-2126, 2007
512007
A new class of selective myocardial calcium channel modulators. 2. Role of the acetal chain in oxadiazol-3-one derivatives
R Budriesi, E Carosati, A Chiarini, B Cosimelli, G Cruciani, P Ioan, ...
Journal of medicinal chemistry 48 (7), 2445-2456, 2005
492005
QSAR modeling and data mining link Torsades de Pointes risk to the interplay of extent of metabolism, active transport, and HERG liability
F Broccatelli, R Mannhold, A Moriconi, S Giuli, E Carosati
Molecular pharmaceutics 9 (8), 2290-2301, 2012
452012
Transporter‐mediated efflux influences CNS side effects: ABCB1, from antitarget to target
F Broccatelli, E Carosati, G Cruciani, TI Oprea
Molecular informatics 29 (1‐2), 16-26, 2010
452010
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