Genomic hallmarks of localized, non-indolent prostate cancer M Fraser, VY Sabelnykova, TN Yamaguchi, LE Heisler, J Livingstone, ... Nature 541 (7637), 359-364, 2017 | 593 | 2017 |
Mutant IDH1 downregulates ATM and alters DNA repair and sensitivity to DNA damage independent of TET2 S Inoue, WY Li, A Tseng, I Beerman, AJ Elia, SC Bendall, F Lemonnier, ... Cancer cell 30 (2), 337-348, 2016 | 207 | 2016 |
The proteogenomic landscape of curable prostate cancer A Sinha, V Huang, J Livingstone, J Wang, NS Fox, N Kurganovs, ... Cancer Cell 35 (3), 414-427. e6, 2019 | 192 | 2019 |
TMPRSS2–ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer KJ Kron, A Murison, S Zhou, V Huang, TN Yamaguchi, YJ Shiah, M Fraser, ... Nature genetics 49 (9), 1336-1345, 2017 | 179 | 2017 |
Prognostic impact of intraductal carcinoma and large cribriform carcinoma architecture after prostatectomy in a contemporary cohort D Trudel, MR Downes, J Sykes, KJ Kron, J Trachtenberg, ... European Journal of Cancer 50 (9), 1610-1616, 2014 | 178 | 2014 |
Association of tissue promoter methylation levels of APC, TGFβ2, HOXD3 and RASSF1A with prostate cancer progression L Liu, KJ Kron, VV Pethe, N Demetrashvili, ME Nesbitt, J Trachtenberg, ... International journal of cancer 129 (10), 2454-2462, 2011 | 118 | 2011 |
Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays K Kron, V Pethe, L Briollais, B Sadikovic, H Ozcelik, A Sunderji, ... PloS one 4 (3), e4830, 2009 | 110 | 2009 |
Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation F Antignano, K Burrows, MR Hughes, JM Han, KJ Kron, NM Penrod, ... The Journal of clinical investigation 124 (5), 1945-1955, 2014 | 105 | 2014 |
Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer SD Bailey, K Desai, KJ Kron, P Mazrooei, NA Sinnott-Armstrong, ... Nature genetics 48 (10), 1260-1266, 2016 | 94 | 2016 |
DNA methylation of HOXD3 as a marker of prostate cancer progression KJ Kron, L Liu, VV Pethe, N Demetrashvili, ME Nesbitt, J Trachtenberg, ... Laboratory investigation 90 (7), 1060-1067, 2010 | 75 | 2010 |
Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer S Zhou, JR Hawley, F Soares, G Grillo, M Teng, SA Madani Tonekaboni, ... Nature communications 11 (1), 441, 2020 | 66 | 2020 |
Correlation of ERG expression and DNA methylation biomarkers with adverse clinicopathologic features of prostate cancer K Kron, L Liu, D Trudel, V Pethe, J Trachtenberg, N Fleshner, B Bapat, ... Clinical cancer research 18 (10), 2896-2904, 2012 | 66 | 2012 |
Enhancer alterations in cancer: a source for a cell identity crisis KJ Kron, SD Bailey, M Lupien Genome medicine 6, 1-12, 2014 | 65 | 2014 |
Novel multiplex MethyLight protocol for detection of DNA methylation in patient tissues and bodily fluids E Olkhov-Mitsel, D Zdravic, K Kron, T van der Kwast, N Fleshner, B Bapat Scientific reports 4 (1), 1-8, 2014 | 65 | 2014 |
Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression P Saraon, D Trudel, K Kron, A Dmitromanolakis, J Trachtenberg, B Bapat, ... The Prostate 74 (4), 372-380, 2014 | 59 | 2014 |
The transition from quiescent to activated states in human hematopoietic stem cells is governed by dynamic 3D genome reorganization N Takayama, A Murison, S Takayanagi, C Arlidge, S Zhou, L Garcia-Prat, ... Cell stem cell 28 (3), 488-501. e10, 2021 | 58 | 2021 |
Quantitative DNA methylation analysis of genes coding for kallikrein-related peptidases 6 and 10 as biomarkers for prostate cancer E Olkhov-Mitsel, T Van der Kwast, K Kron, H Ozcelik, L Briollais, ... Epigenetics 7 (9), 1037-1045, 2012 | 55 | 2012 |
Transcriptome-wide off-target effects of steric-blocking oligonucleotides EM Holgersen, S Gandhi, Y Zhou, J Kim, B Vaz, J Bogojeski, M Bugno, ... nucleic acid therapeutics 31 (6), 392-403, 2021 | 52 | 2021 |
Cistrome partitioning reveals convergence of somatic mutations and risk variants on master transcription regulators in primary prostate tumors P Mazrooei, KJ Kron, Y Zhu, S Zhou, G Grillo, T Mehdi, M Ahmed, ... Cancer Cell 36 (6), 674-689. e6, 2019 | 52 | 2019 |
Epigenome-wide DNA methylation profiling identifies differential methylation biomarkers in high-grade bladder cancer E Olkhov-Mitsel, AJ Savio, KJ Kron, VV Pethe, T Hermanns, NE Fleshner, ... Translational oncology 10 (2), 168-177, 2017 | 34 | 2017 |