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Jacob Witten
Jacob Witten
Computational and Systems Biology Program, MIT
Verified email at mit.edu
Title
Cited by
Cited by
Year
The particle in the spider's web: transport through biological hydrogels
J Witten, K Ribbeck
Nanoscale 9 (24), 8080-8095, 2017
1532017
Selective permeability of mucus barriers
J Witten, T Samad, K Ribbeck
Current opinion in biotechnology 52, 124-133, 2018
1212018
Deep learning regression model for antimicrobial peptide design
J Witten, Z Witten
BioRxiv, 692681, 2019
492019
Mucus and Mucin Environments Reduce the Efficacy of Polymyxin and Fluoroquinolone Antibiotics against Pseudomonas aeruginosa
T Samad, JY Co, J Witten, K Ribbeck
ACS biomaterials science & engineering 5 (3), 1189-1194, 2019
412019
Molecular characterization of mucus binding
J Witten, T Samad, K Ribbeck
Biomacromolecules 20 (4), 1505-1513, 2019
372019
Probing the potential of mucus permeability to signify preterm birth risk
KB Smith-Dupont, CE Wagner, J Witten, K Conroy, H Rudoltz, K Pagidas, ...
Scientific reports 7 (1), 10302, 2017
362017
Micro-heterogeneity metrics for diffusion in soft matter
J Mellnik, PA Vasquez, SA McKinley, J Witten, DB Hill, MG Forest
Soft matter 10 (39), 7781-7796, 2014
232014
Enhancing the immunogenicity of lipid-nanoparticle mRNA vaccines by adjuvanting the ionizable lipid and the mRNA
B Li, AY Jiang, I Raji, C Atyeo, TM Raimondo, AGR Gordon, LH Rhym, ...
Nature Biomedical Engineering, 1-18, 2023
152023
Computational insights into avidity of polymeric multivalent binders
E Zumbro, J Witten, A Alexander-Katz
Biophysical Journal 117 (5), 892-902, 2019
152019
Charge influences substrate recognition and self-assembly of hydrophobic FG sequences
WG Chen, J Witten, SC Grindy, N Holten-Andersen, K Ribbeck
Biophysical journal 113 (9), 2088-2099, 2017
142017
Preparation of two novel monobrominated 2-(2′, 4′-dihydroxybenzoyl)-3, 4, 5, 6-tetrachlorobenzoic acids and their separation from crude synthetic mixtures using vortex …
A Weisz, JJ Witten, Y Zeng, EP Mazzola, Y Ito
Journal of Chromatography A 1237, 106-114, 2012
122012
Comparison of physicochemical properties of native mucus and reconstituted mucin gels
CE Wagner, M Krupkin, KB Smith-Dupont, CM Wu, NA Bustos, J Witten, ...
Biomacromolecules 24 (2), 628-639, 2023
112023
Mapping protein conformational landscapes under strongly native conditions with hydrogen exchange mass spectrometry
J Witten, A Ruschak, T Poterba, A Jaramillo, AD Miranker, SS Jaswal
The Journal of Physical Chemistry B 119 (31), 10016-10024, 2015
82015
Combinatorial development of nebulized mRNA delivery formulations for the lungs
AY Jiang, J Witten, IO Raji, F Eweje, C MacIsaac, S Meng, FA Oladimeji, ...
Nature nanotechnology 19 (3), 364-375, 2024
72024
Vortex counter-current chromatography: Performance of a new preparative column
Y Ito, R Clary, JJ Witten, Y Zeng
Chromatographia 75, 1091-1097, 2012
52012
Recent advances in nanoparticulate RNA delivery systems
J Witten, Y Hu, R Langer, DG Anderson
Proceedings of the National Academy of Sciences 121 (11), e2307798120, 2024
42024
Spatial configuration of charge and hydrophobicity tune particle transport through mucus
T Samad, J Witten, AJ Grodzinsky, K Ribbeck
Biophysical Journal 121 (2), 277-287, 2022
32022
Ionizable lipids and compositions and uses thereof
DG Anderson, LH Rhym, A Jiang, J Witten, I Raji
US Patent App. 18/080,299, 2023
2023
Optimized Lipid Nanoparticles and Delivery Conditions for State-of-the-Art Nebulized mRNA Delivery to the Lungs
A Jiang, J Witten, I Raji, S Eweje, C MacIsaac, F Oladimeji, R Langer, ...
2022 AIChE Annual Meeting, 2022
2022
Understanding the selective permeability of biological hydrogels
JJS Witten
Massachusetts Institute of Technology, 2019
2019
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Articles 1–20