SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation K Schubert, ED Karousis, A Jomaa, A Scaiola, B Echeverria, LA Gurzeler, ... Nature structural & molecular biology 27 (10), 959-966, 2020 | 519 | 2020 |
Nonsense‐mediated mRNA decay: novel mechanistic insights and biological impact ED Karousis, S Nasif, O Mühlemann Wiley Interdisciplinary Reviews: RNA 7 (5), 661-682, 2016 | 195 | 2016 |
Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6-and SMG7-mediated degradation pathways M Colombo, ED Karousis, J Bourquin, R Bruggmann, O Mühlemann Rna 23 (2), 189-201, 2017 | 184 | 2017 |
Nonsense-mediated mRNA decay begins where translation ends ED Karousis, O Mühlemann Cold Spring Harbor perspectives in biology 11 (2), a032862, 2019 | 176 | 2019 |
Nanopore sequencing reveals endogenous NMD-targeted isoforms in human cells OM Evangelos D. Karousis, Foivos Gypas, Mihaela Zavolan Genome Biology 22, 2021 | 42 | 2021 |
Human NMD ensues independently of stable ribosome stalling ED Karousis, LA Gurzeler, G Annibaldis, R Dreos, O Mühlemann Nature communications 11 (1), 4134, 2020 | 31 | 2020 |
The broader sense of nonsense ED Karousis, O Mühlemann Trends in biochemical sciences 47 (11), 921-935, 2022 | 30 | 2022 |
New functions in translation termination uncovered for NMD factor UPF 3B O Mühlemann, ED Karousis The EMBO journal 36 (20), 2928-2930, 2017 | 9 | 2017 |
Universal features of Nsp1-mediated translational shutdown by coronaviruses K Schubert, ED Karousis, I Ban, CP Lapointe, M Leibundgut, E Bäumlin, ... Molecular cell 83 (19), 3546-3557. e8, 2023 | 8 | 2023 |
Production of human translation-competent lysates using dual centrifugation LA Gurzeler, J Ziegelmüller, O Mühlemann, ED Karousis RNA biology 19 (1), 78-88, 2022 | 8 | 2022 |
A subtle alternative splicing event gives rise to a widely expressed human RNase k isoform ED Karousis, DC Sideris Plos one 9 (5), e96557, 2014 | 5 | 2014 |
Coronavirus takeover of host cell translation and intracellular antiviral response: a molecular perspective ED Karousis, K Schubert, N Ban The EMBO journal 43 (2), 151-167, 2024 | 1 | 2024 |
The art of hijacking: how Nsp1 impacts host gene expression during coronaviral infections ED Karousis Biochemical Society Transactions, BST20231119, 2024 | | 2024 |
Universal features of Nsp1-mediated translational shutdown by coronaviruses (preprint) K Schubert, ED Karousis, I Ban, C Lapointe, M Leibundgut, E Baeumlin, ... | | 2023 |
Sars-cov-2 nsp1 binds the ribosomal mrna channel to inhibit translation (vol 27, pg 959, 2020) K Schubert, ED Karousis, A Jomaa, A Scaiola, B Echeverria, LA Gurzeler, ... Nature Structural & Molecular Biology 27 (11), 1094-1094, 2020 | | 2020 |
Nonsense-mediated mRNA decay (NMD) restricts replication of mammalian RNA viruses E Karousis | | 2015 |
Asn53Ser SNP alters human RNase kappa enzymatic activity IK Kokkinopoulou, ED Karousis, D Sideris FEBS JOURNAL 281, 676-677, 2014 | | 2014 |
Identification, cloning and expression of a human RNase kappa isoform arising from subtle alternative splicing ED Karousis, EG Fragoulis, DC Sideris FEBS JOURNAL 278, 461-462, 2011 | | 2011 |