| Spectroscopic recognition of guanine dimeric hairpin quadruplexes by a carbocyanine dye. Q Chen, ID Kuntz, RH Shafer Proceedings of the National Academy of Sciences 93 (7), 2635-2639, 1996 | 182 | 1996 |
| Identification of LY2510924, a novel cyclic peptide CXCR4 antagonist that exhibits antitumor activities in solid tumor and breast cancer metastatic models SB Peng, X Zhang, D Paul, LM Kays, W Gough, J Stewart, MT Uhlik, ... Molecular cancer therapeutics 14 (2), 480-490, 2015 | 133 | 2015 |
| Structure-based discovery of ligands targeted to the RNA double helix Q Chen, RH Shafer, ID Kuntz Biochemistry 36 (38), 11402-11407, 1997 | 117 | 1997 |
| Carboxylic acid derivatives that inhibit the binding of integrins to their receptors RJ Biediger, Q Chen, ER Decker, GW Holland, JM Kassir, W Li, ... US Patent 6,972,296, 2005 | 78 | 2005 |
| Structural insights into probe-dependent positive allosterism of the GLP-1 receptor AB Bueno, B Sun, FS Willard, D Feng, JD Ho, DB Wainscott, ... Nature Chemical Biology 16 (10), 1105-1110, 2020 | 61 | 2020 |
| The discovery, preclinical, and early clinical development of potent and selective GPR40 agonists for the treatment of type 2 diabetes mellitus (LY2881835, LY2922083, and … C Hamdouchi, SD Kahl, A Patel Lewis, GR Cardona, RW Zink, K Chen, ... Journal of Medicinal Chemistry 59 (24), 10891-10916, 2016 | 56 | 2016 |
| Structural determinants of dual incretin receptor agonism by tirzepatide B Sun, FS Willard, D Feng, J Alsina-Fernandez, Q Chen, M Vieth, JD Ho, ... Proceedings of the National Academy of Sciences 119 (13), e2116506119, 2022 | 50 | 2022 |
| Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1 … J Hao, JP Beck, JM Schaus, JH Krushinski, Q Chen, CD Beadle, P Vidal, ... Journal of Medicinal Chemistry 62 (19), 8711-8732, 2019 | 49 | 2019 |
| A 3D structure model of integrin α4β1 complex: I. Construction of a homology model of β1 and ligand binding analysis TJ You, DS Maxwell, TP Kogan, Q Chen, J Li, J Kassir, GW Holland, ... Biophysical journal 82 (1), 447-457, 2002 | 38 | 2002 |
| Endothelin Antagonists: Substituted Mesitylcarboxamides with High Potency and Selectivity for ETA Receptors C Wu, ER Decker, N Blok, H Bui, Q Chen, B Raju, AR Bourgoyne, ... Journal of medicinal chemistry 42 (22), 4485-4499, 1999 | 35 | 1999 |
| Synthesis and Pharmacological Characterization of C4β-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1S,2S,4S,5R,6S)-2-Amino-4 … JA Monn, SS Henry, SM Massey, DK Clawson, Q Chen, BA Diseroad, ... Journal of medicinal chemistry 61 (6), 2303-2328, 2018 | 25 | 2018 |
| Geometric accuracy of three-dimensional molecular overlays Q Chen, RE Higgs, M Vieth Journal of chemical information and modeling 46 (5), 1996-2002, 2006 | 19 | 2006 |
| Determination of L-AP4-bound human mGlu8 receptor amino terminal domain structure and the molecular basis for L-AP4’s group III mGlu receptor functional potency and selectivity JM Schkeryantz, Q Chen, JD Ho, S Atwell, A Zhang, MC Vargas, J Wang, ... Bioorganic & medicinal chemistry letters 28 (4), 612-617, 2018 | 14 | 2018 |
| Reconstruction of 3D structures of MET antibodies from electron microscopy 2D class averages Q Chen, M Vieth, DE Timm, C Humblet, D Schneidman-Duhovny, ... PLoS One 12 (4), e0175758, 2017 | 13 | 2017 |
| A 3D QSAR analysis of in vitro binding affinity and selectivity of 3‐isoxazolylsulfonylaminothiophenes as endothelin receptor antagonists Q Chen, C Wu, D Maxwell, GA Krudy, RAF Dixon, TJ You Quantitative Structure‐Activity Relationships 18 (2), 124-133, 1999 | 13 | 1999 |
| Discovery of an orally efficacious positive allosteric modulator of the glucagon-like peptide-1 receptor FS Willard, DB Wainscott, AD Showalter, C Stutsman, W Ma, GR Cardona, ... Journal of Medicinal Chemistry 64 (6), 3439-3448, 2021 | 12 | 2021 |
| Activation of the human insulin receptor by non-insulin-related peptides NS Kirk, Q Chen, YG Wu, AL Asante, H Hu, JF Espinosa, F Martinez-Olid, ... Nat Commun 13 (1), 5695, 2022 | 10 | 2022 |
| Structural Basis for (S)-3,4-Dicarboxyphenylglycine (DCPG) As a Potent and Subtype Selective Agonist of the mGlu8 Receptor Q Chen, JD Ho, S Ashok, MC Vargas, J Wang, S Atwell, M Bures, ... Journal of medicinal chemistry 61 (22), 10040-10052, 2018 | 9 | 2018 |
| Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT1F receptor agonists: Evolution from bicyclic to monocyclic cores D Zhang, MJ Blanco, BP Ying, D Kohlman, SX Liang, F Victor, Q Chen, ... Bioorganic & Medicinal Chemistry Letters 25 (19), 4337-4341, 2015 | 9 | 2015 |
| An Efficient Palladium-Catalysed Aminocarbonylation of Benzyl Chlorides E Rilvin-Derrick, N Oram, J Richardson Synlett 31 (04), 369-372, 2020 | 8 | 2020 |
Maria-Jesus BlancoAtavistik BioVerified email at atavistikbio.com
