Tudor Oprea - Google Scholar Citations

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Cristian BologaResearch Professor, University of New MexicoVerified email at salud.unm.edu
Oleg UrsuResearch Asst Professor, University of New MexicoVerified email at salud.unm.edu
Eric R. ProssnitzDistinguished Professor & Chief, Div. of Molecular Medicine, Dept. of Internal Medicine, UNMVerified email at salud.unm.edu
Garland R. MarshallProfesso of Biochemistry and Molecular Biophysics, Washington UniversityVerified email at biochem.wustl.edu
Jeremy J YangUniversity of New MexicoVerified email at salud.unm.edu
Liliana Ostopovici-HalipThe Institute of Chemistry, TimisoaraVerified email at acad-icht.tm.edu.ro
Andrei LeitãoProfessor Doutor - Instituto de Química de São Carlos, Universidade de São PauloVerified email at iqsc.usp.br
Paul LeesonPaul Leeson Consulting LtdVerified email at nottingham.ac.uk
Ramona CurpanResearcher, Institute of Chemistry Timisoara of Romanian AcademyVerified email at acad-icht.tm.edu.ro
Andrew M DavisAstraZeneca, Fisons, Astra, University of KentVerified email at astrazeneca.com
Stephen L MathiasSr Research Scientist, University of New Mexico Translational Informatics DivisionVerified email at swcp.com
Alexander TropshaProfessor at UNC-Chapel HillVerified email at unc.edu
Søren BrunakProfessor of Disease Systems Biology, University of CopenhagenVerified email at cpr.ku.dk
Chetana RevankarScientist, Life TechnologiesVerified email at lifetech.com
Fabio BroccatelliScientist at GenentechVerified email at gene.com
Benet lzUCSFVerified email at ucsf.edu
Ramesh ChinnasamyCollege Assistant Professor, Chemistry, New Mexico State UniversityVerified email at nmsu.edu
Tione BurandaUniversity of New Mexico school of Medicine, PathologyVerified email at salud.unm.edu
Steffen RennerInvestigator at NovartisVerified email at novartis.com
Jordi MestresIMIM Hospital del Mar Medical Research InstituteVerified email at imim.es

Tudor Oprea

Professor and Chief, Translational Informatics Division, UNM School

Verified email at salud.unm.edu - Homepage

virtual screening cheminformatics drug repositioning QSAR drug discovery


Title	Cited by	Year
Is There a Difference Between Leads and Drugs? A Historical Perspective. TI Oprea, AM Davis, SJ Teague, PD Leeson Journal of chemical information and computer sciences 41 (5), 1308-1315, 2001	852	2001
The design of leadlike combinatorial libraries SJ Teague, AM Davis, PD Leeson, T Oprea Angewandte Chemie International Edition 38 (24), 3743-3748, 1999	737	1999
Virtual and biomolecular screening converge on a selective agonist for GPR30 CG Bologa, CM Revankar, SM Young, BS Edwards, JB Arterburn, ... Nature chemical biology 2 (4), 207-212, 2006	717	2006
A comprehensive map of molecular drug targets R Santos, O Ursu, A Gaulton, AP Bento, RS Donadi, CG Bologa, ... Nature reviews Drug discovery 16 (1), 19, 2017	656	2017
Estrogen signaling through the transmembrane G protein–coupled receptor GPR30 ER Prossnitz, JB Arterburn, HO Smith, TI Oprea, LA Sklar, HJ Hathaway Annu. Rev. Physiol. 70, 165-190, 2008	593	2008
Property distribution of drug-related chemical databases TI Oprea Journal of computer-aided molecular design 14 (3), 251-264, 2000	558	2000
Pursuing the leadlikeness concept in pharmaceutical research MM Hann, TI Oprea Current opinion in chemical biology 8 (3), 255-263, 2004	512	2004
Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system E Brailoiu, SL Dun, GC Brailoiu, K Mizuo, LA Sklar, TI Oprea, ER Prossnitz, ... Journal of endocrinology 193 (2), 311-321, 2007	437	2007
In vivo effects of a GPR30 antagonist MK Dennis, R Burai, C Ramesh, WK Petrie, SN Alcon, TK Nayak, ... Nature chemical biology 5 (6), 421, 2009	435	2009
G protein–coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17β-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells L Albanito, A Madeo, R Lappano, A Vivacqua, V Rago, A Carpino, ... Cancer research 67 (4), 1859-1866, 2007	420	2007
BDDCS applied to over 900 drugs LZ Benet, F Broccatelli, TI Oprea The AAPS journal 13 (4), 519-547, 2011	414	2011
Chemography: the art of navigating in chemical space TI Oprea, J Gottfries Journal of combinatorial chemistry 3 (2), 157-166, 2001	320	2001
Integrating virtual screening in lead discovery TI Oprea, H Matter Current opinion in chemical biology 8 (4), 349-358, 2004	305	2004
VALIDATE: A new method for the receptor-based prediction of binding affinities of novel ligands RD Head, ML Smythe, TI Oprea, CL Waller, SM Green, GR Marshall Journal of the American Chemical society 118 (16), 3959-3969, 1996	304	1996
Current trends in lead discovery: Are we looking at the appropriate property TI Oprea Journal of computer-aided molecular design 16 (5-6), 325-334, 2002	277*	2002
Novel chemical space exploration via natural products J Rosén, J Gottfries, S Muresan, A Backlund, TI Oprea Journal of medicinal chemistry 52 (7), 1953-1962, 2009	239	2009
Flow cytometry for high-throughput, high-content screening BS Edwards, T Oprea, ER Prossnitz, LA Sklar Current opinion in chemical biology 8 (4), 392-398, 2004	232	2004
Ligand-based identification of environmental estrogens CL Waller, TI Oprea, K Chae, HK Park, KS Korach, SC Laws, TE Wiese, ... Chemical research in toxicology 9 (8), 1240-1248, 1996	232	1996
The G protein–coupled receptor GPR30 inhibits proliferation of estrogen receptor–positive breast cancer cells EA Ariazi, E Brailoiu, S Yerrum, HA Shupp, MJ Slifker, HE Cunliffe, ... Cancer research 70 (3), 1184-1194, 2010	219	2010
Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity MK Dennis, AS Field, R Burai, C Ramesh, WK Petrie, CG Bologa, ... The Journal of steroid biochemistry and molecular biology 127 (3-5), 358-366, 2011	217	2011

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