Systems toxicology approaches for understanding the joint effects of environmental chemical mixtures DJ Spurgeon, OAH Jones, JLCM Dorne, C Svendsen, S Swain, ... Science of the total environment 408 (18), 3725-3734, 2010 | 199 | 2010 |
Risk assessment of coccidostatics during feed cross-contamination: animal and human health aspects J Dorne, ML Fernández-Cruz, U Bertelsen, DW Renshaw, K Peltonen, ... Toxicology and applied pharmacology 270 (3), 196-208, 2013 | 130 | 2013 |
The refinement of uncertainty/safety factors in risk assessment by the incorporation of data on toxicokinetic variability in humans J Dorne, AG Renwick Toxicological Sciences 86 (1), 20-26, 2005 | 125 | 2005 |
An analysis of the need for an additional uncertainty factor for infants and children AG Renwick, JL Dorne, K Walton Regulatory Toxicology and Pharmacology 31 (3), 286-296, 2000 | 122 | 2000 |
Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review J Dorne, K Walton, AG Renwick Food and chemical toxicology 43 (2), 203-216, 2005 | 119 | 2005 |
Nitrite in feed: from animal health to human health A Cockburn, G Brambilla, ML Fernández, D Arcella, LR Bordajandi, ... Toxicology and applied pharmacology 270 (3), 209-217, 2013 | 115 | 2013 |
Recent advances in the risk assessment of melamine and cyanuric acid in animal feed JL Dorne, DR Doerge, M Vandenbroeck, J Fink-Gremmels, W Mennes, ... Toxicology and applied pharmacology 270 (3), 218-229, 2013 | 110 | 2013 |
Current EU research activities on combined exposure to multiple chemicals SK Bopp, R Barouki, W Brack, S Dalla Costa, JLCM Dorne, PE Drakvik, ... Environment international 120, 544-562, 2018 | 106 | 2018 |
Human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for risk assessment J Dorne, K Walton, AG Renwick Food and Chemical Toxicology 41 (2), 201-224, 2003 | 98 | 2003 |
Guidance on the use of the weight of evidence approach in scientific assessments EFSA Scientific Committee, A Hardy, D Benford, T Halldorsson, MJ Jeger, ... EFSA Journal 15 (8), e04971, 2017 | 95 | 2017 |
Uncertainty factors for chemical risk assessment: human variability in the pharmacokinetics of CYP1A2 probe substrates J Dorne, K Walton, AG Renwick Food and Chemical Toxicology 39 (7), 681-696, 2001 | 92 | 2001 |
Human risk assessment of heavy metals: principles and applications JL Dorne, GE Kass, LR Bordajandi, B Amzal, U Bertelsen, AF Castoldi, ... Met Ions Life Sci 8 (4), 27-60, 2011 | 88 | 2011 |
Uncertainty factors for chemical risk assessment: interspecies differences in the in vivo pharmacokinetics and metabolism of human CYP1A2 substrates K Walton, JL Dorne, AG Renwick Food and Chemical Toxicology 39 (7), 667-680, 2001 | 87 | 2001 |
Guidance on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals SJ More, V Bampidis, D Benford, SH Bennekou, C Bragard, ... Efsa journal 17 (3), 2019 | 85 | 2019 |
The effects on terrestrial invertebrates of reducing pesticide inputs in arable crop edges: a meta‐analysis GK Frampton, JLCM Dorne Journal of Applied Ecology 44 (2), 362-373, 2007 | 77 | 2007 |
Human and environmental risk assessment of pharmaceuticals: differences, similarities, lessons from toxicology J Dorne, L Skinner, GK Frampton, DJ Spurgeon, AMJ Ragas Analytical and Bioanalytical Chemistry 387 (4), 1259-1268, 2007 | 76 | 2007 |
Comparative toxicity of pesticides and environmental contaminants in bees: are honey bees a useful proxy for wild bee species? MS Heard, J Baas, JL Dorne, E Lahive, AG Robinson, A Rortais, ... Science of the Total Environment 578, 357-365, 2017 | 72 | 2017 |
Combining analytical techniques, exposure assessment and biological effects for risk assessment of chemicals in food J Dorne, LR Bordajandi, B Amzal, P Ferrari, P Verger TrAC Trends in Analytical Chemistry 28 (6), 695-707, 2009 | 72 | 2009 |
Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate? J Dorne, K Walton, W Slob, AG Renwick Food and Chemical Toxicology 40 (11), 1633-1656, 2002 | 71 | 2002 |
Metabolism, variability and risk assessment J Dorne Toxicology 268 (3), 156-164, 2010 | 69 | 2010 |