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Trevor Penning
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Role of quinones in toxicology
JL Bolton, MA Trush, TM Penning, G Dryhurst, TJ Monks
Chemical research in toxicology 13 (3), 135-160, 2000
18912000
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
M Stanbrough, GJ Bubley, K Ross, TR Golub, MA Rubin, TM Penning, ...
Cancer research 66 (5), 2815-2825, 2006
12662006
Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1–AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the …
TM Penning, ME Burczynski, JM Jez, CF Hung, HK Lin, H Ma, M Moore, ...
Biochemical journal 351 (1), 67-77, 2000
7122000
Comparative anatomy of the aldo–keto reductase superfamily
JM Jez, MJ Bennett, BP Schlegel, M Lewis, TM Penning
Biochemical Journal 326 (3), 625-636, 1997
7071997
Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
LE Tebay, H Robertson, ST Durant, SR Vitale, TM Penning, ...
Free Radical Biology and Medicine 88, 108-146, 2015
6532015
Molecular endocrinology of hydroxysteroid dehydrogenases
TM Penning
Endocrine reviews 18 (3), 281-305, 1997
5681997
Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation: generation of reactive and redox active o-quinones
TM Penning, ME Burczynski, CF Hung, KD McCoull, NT Palackal, ...
Chemical research in toxicology 12 (1), 1-18, 1999
5501999
The biochemical basis for increased testosterone production in theca cells propagated from patients with polycystic ovary syndrome
VL Nelson, K Qin, RL Rosenfield, JR Wood, TM Penning, RS Legro, ...
The Journal of Clinical Endocrinology & Metabolism 86 (12), 5925-5933, 2001
4832001
A new nomenclature for the aldo-keto reductase superfamily
JM Jez, TG Flynn, TM Penning
Biochemical pharmacology 54 (6), 639-647, 1997
4261997
Aldo-keto reductases and bioactivation/detoxication
Y Jin, TM Penning
Annu. Rev. Pharmacol. Toxicol. 47, 263-292, 2007
3962007
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative
B Persson, Y Kallberg, JE Bray, E Bruford, SL Dellaporta, AD Favia, ...
Chemico-biological interactions 178 (1-3), 94-98, 2009
3922009
The aldo-keto reductase superfamily homepage
D Hyndman, DR Bauman, VV Heredia, TM Penning
Chemico-biological interactions 143, 621-631, 2003
3512003
The aldo-keto reductases (AKRs): Overview
TM Penning
Chemico-biological interactions 234, 236-246, 2015
3472015
Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer
KE Knudsen, TM Penning
Trends in Endocrinology & Metabolism 21 (5), 315-324, 2010
3252010
Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1–NRF2 pathway, and not the BACH1–NRF2 pathway …
AK MacLeod, M McMahon, SM Plummer, LG Higgins, TM Penning, ...
Carcinogenesis 30 (9), 1571-1580, 2009
3192009
Resveratrol is a peroxidase-mediated inactivator of COX-1 but not COX-2: a mechanistic approach to the design of COX-1 selective agents
LM Szewczuk, L Forti, LA Stivala, TM Penning
Journal of biological chemistry 279 (21), 22727-22737, 2004
2962004
Human aldo–keto reductases: function, gene regulation, and single nucleotide polymorphisms
TM Penning, JE Drury
Archives of biochemistry and biophysics 464 (2), 241-250, 2007
2922007
The aldo-keto reductase (AKR) superfamily: an update
JM Jez, TM Penning
Chemico-biological interactions 130, 499-525, 2001
2902001
Human cytosolic 3α-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3β-hydroxysteroid dehydrogenase activity: implications for steroid …
S Steckelbroeck, Y Jin, S Gopishetty, B Oyesanmi, TM Penning
Journal of biological chemistry 279 (11), 10784-10795, 2004
2862004
Generation of reactive oxygen species during the enzymatic oxidation of polycyclic aromatic hydrocarbon trans-dihydrodiols catalyzed by dihydrodiol dehydrogenase
TM Penning, ST Ohnishi, T Ohnishi, RG Harvey
Chemical research in toxicology 9 (1), 84-92, 1996
2801996
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Articles 1–20