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Timothy Sheils
Timothy Sheils
Unknown affiliation
Verified email at nih.gov
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Cited by
Year
Pharos: collating protein information to shed light on the druggable genome
DT Nguyen, S Mathias, C Bologa, S Brunak, N Fernandez, A Gaulton, ...
Nucleic acids research 45 (D1), D995-D1002, 2017
2542017
TCRD and Pharos 2021: mining the human proteome for disease biology
TK Sheils, SL Mathias, KJ Kelleher, VB Siramshetty, DT Nguyen, ...
Nucleic Acids Research 49 (D1), D1334-D1346, 2021
1172021
CATMoS: collaborative acute toxicity modeling suite
K Mansouri, AL Karmaus, J Fitzpatrick, G Patlewicz, P Pradeep, D Alberga, ...
Environmental health perspectives 129 (4), 047013, 2021
852021
Novel consensus architecture to improve performance of large-scale multitask deep learning QSAR models
AV Zakharov, T Zhao, DT Nguyen, T Peryea, T Sheils, A Yasgar, R Huang, ...
Journal of chemical information and modeling 59 (11), 4613-4624, 2019
552019
How to illuminate the druggable genome using pharos
T Sheils, SL Mathias, VB Siramshetty, G Bocci, CG Bologa, JJ Yang, ...
Current protocols in bioinformatics 69 (1), e92, 2020
352020
Pharos 2023: an integrated resource for the understudied human proteome
KJ Kelleher, TK Sheils, SL Mathias, JJ Yang, VT Metzger, VB Siramshetty, ...
Nucleic acids research 51 (D1), D1405-D1416, 2023
252023
NCATS Inxight Drugs: a comprehensive and curated portal for translational research
VB Siramshetty, I Grishagin, ÐT Nguyễn, T Peryea, Y Skovpen, ...
Nucleic Acids Research 50 (D1), D1307-D1316, 2022
232022
SmartGraph: a network pharmacology investigation platform
G Zahoránszky-Kőhalmi, T Sheils, TI Oprea
Journal of cheminformatics 12, 1-11, 2020
182020
RaMP-DB 2.0: a renovated knowledgebase for deriving biological and chemical insight from metabolites, proteins, and genes
J Braisted, A Patt, C Tindall, T Sheils, J Neyra, K Spencer, T Eicher, ...
Bioinformatics 39 (1), btac726, 2023
122023
Scientific evidence based rare disease research discovery with research funding data in knowledge graph
Q Zhu, ÐT Nguyễn, T Sheils, G Alyea, E Sid, Y Xu, J Dickens, EA Mathé, ...
Orphanet Journal of Rare Diseases 16, 1-12, 2021
112021
Getting started with the IDG KMC datasets and tools
E Kropiwnicki, JL Binder, JJ Yang, J Holmes, A Lachmann, DJB Clarke, ...
Current protocols 2 (1), e355, 2022
72022
Smartgraph: a network pharmacology investigation platform
ZK Gergely, T Sheils, TI Oprea
Journal of Cheminformatics 12 (1), 2020
42020
Collaborative Use Repurposing Engine (CURE): FDA-NCATS/NIH Effort to Capture the Global Clinical Experience of Drug Repurposing to Facilitate Development of New Treatments for …
H Stone, L Sacks, R Tiernan, M Duggal, T Sheils, N Southall
Open forum infectious diseases 4 (Suppl 1), S12, 2017
12017
Pharos and TCRD: Informatics Tools for Illuminating Dark Targets
KJ Kelleher, TK Sheils, SL Mathias, DT Nguyen, V Siramshetty, A Pillai, ...
Open Access Databases and Datasets for Drug Discovery, 231-267, 2024
2024
SmartGraph API: Programmatic Knowledge Mining in Network-Pharmacology Setting
G Zahoránszky-Kőhalmi, B Walker, N Miller, B Yang, DVL Penna, J Binder, ...
2024
Overview of the Knowledge Management Center for Illuminating the Druggable Genome
T Oprea, C Bologa, J Holmes, S Mathias, VT Metzger, A Waller, JJ Yang, ...
Drug Discovery Today, 103882, 2024
2024
Pharos: Open-source target illumination platform
T Sheils, DT Nguyen, V Siramshetty, N Southall, T Oprea
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
Leveling the playing field: Illuminating understudied targets with Pharos
T Sheils, DT Nguyen, N Southall, T Oprea, V Siramshetty
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
How to present knowledge about dark targets from 60 data sources and 10 data types
T Sheils, DT Nguyen, R Guha, N Southall
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
Pharos-shining light on the druggable genome
DT Nguyen, T Sheils, G Mandava, A Jadhav, N Southall, R Guha
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
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