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Elaine Bignell
Elaine Bignell
MRC Centre for Medical Mycology, University of Exeter
Adresse e-mail validée de exeter.ac.uk - Page d'accueil
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Siderophore Biosynthesis But Not Reductive Iron Assimilation Is Essential for Aspergillus fumigatus Virulence
M Schrettl, E Bignell, C Kragl, C Joechl, T Rogers, HN Arst Jr, K Haynes, ...
The Journal of experimental medicine 200 (9), 1213-1219, 2004
5482004
Distinct roles for intra-and extracellular siderophores during Aspergillus fumigatus infection
M Schrettl, E Bignell, C Kragl, Y Sabiha, O Loss, M Eisendle, A Wallner, ...
PLoS pathogens 3 (9), e128, 2007
4432007
Ambient pH gene regulation in fungi: making connections
MA Peñalva, J Tilburn, E Bignell, HN Arst
Trends in microbiology 16 (6), 291-300, 2008
3892008
Tackling the emerging threat of antifungal resistance to human health
MC Fisher, A Alastruey-Izquierdo, J Berman, T Bicanic, EM Bignell, ...
Nature reviews microbiology 20 (9), 557-571, 2022
3662022
Sub-telomere directed gene expression during initiation of invasive aspergillosis
A McDonagh, ND Fedorova, J Crabtree, Y Yu, S Kim, D Chen, O Loss, ...
PLoS pathogens 4 (9), e1000154, 2008
2732008
Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA
FM Soriani, I Malavazi, ME da Silva Ferreira, M Savoldi, ...
Molecular microbiology 67 (6), 1274-1291, 2008
1902008
The Aspergillus fumigatus transcriptional activator CpcA contributes significantly to the virulence of this fungal pathogen
S Krappmann, EM Bignell, U Reichard, T Rogers, K Haynes, GH Braus
Molecular microbiology 52 (3), 785-799, 2004
1672004
The Aspergillus pH‐responsive transcription factor PacC regulates virulence
E Bignell, S Negrete‐Urtasun, AM Calcagno, K Haynes, HN Arst Jr, ...
Molecular microbiology 55 (4), 1072-1084, 2005
1642005
The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis
M Bertuzzi, M Schrettl, L Alcazar-Fuoli, TC Cairns, A Munoz, LA Walker, ...
PLoS pathogens 10 (10), e1004413, 2014
1572014
Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus
S Yasmin, L Alcazar-Fuoli, M Gründlinger, T Puempel, T Cairns, M Blatzer, ...
Proceedings of the National Academy of Sciences 109 (8), E497-E504, 2012
1282012
Two new genes involved in signalling ambient pH in Aspergillus nidulans
HN Arst, E Bignell, J Tilburn
Molecular and General Genetics MGG 245, 787-790, 1994
1261994
Specificity Determinants of Proteolytic Processing of Aspergillus PacC Transcription Factor Are Remote from the Processing Site, and Processing Occurs in Yeast If …
JM Mingot, J Tilburn, E Diez, E Bignell, M Orejas, DA Widdick, S Sarkar, ...
Molecular and cellular biology 19 (2), 1390-1400, 1999
1041999
Inactivation of Transcription Factor Gene ACE2 in the Fungal Pathogen Candida glabrata Results in Hypervirulence
M Kamran, AM Calcagno, H Findon, E Bignell, MD Jones, P Warn, ...
Eukaryotic cell 3 (2), 546-552, 2004
1002004
The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
T Furukawa, N Van Rhijn, M Fraczek, F Gsaller, E Davies, P Carr, S Gago, ...
Nature communications 11 (1), 427, 2020
942020
Candida glabrata STE12 is required for wild‐type levels of virulence and nitrogen starvation induced filamentation
AM Calcagno, E Bignell, P Warn, MD Jones, DW Denning, ...
Molecular microbiology 50 (4), 1309-1318, 2003
942003
Secondary metabolite arsenal of an opportunistic pathogenic fungus
E Bignell, TC Cairns, K Throckmorton, WC Nierman, NP Keller
Philosophical Transactions of the Royal Society B: Biological Sciences 371 …, 2016
892016
A Regulator of Aspergillus fumigatus Extracellular Proteolytic Activity Is Dispensable for Virulence
A Bergmann, T Hartmann, T Cairns, EM Bignell, S Krappmann
Infection and immunity 77 (9), 4041-4050, 2009
822009
The effects of dsRNA mycoviruses on growth and murine virulence of Aspergillus fumigatus
MF Bhatti, A Jamal, MA Petrou, TC Cairns, EM Bignell, RHA Coutts
Fungal Genetics and Biology 48 (11), 1071-1075, 2011
812011
On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction
EA Espeso, T Roncal, E Díez, L Rainbow, E Bignell, J Álvaro, T Suárez, ...
The EMBO journal 19 (4), 719-728, 2000
812000
Pathogenesis of respiratory viral and fungal coinfections
F Salazar, E Bignell, GD Brown, PC Cook, A Warris
Clinical Microbiology Reviews 35 (1), e00094-21, 2022
742022
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