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Alshad S. Lalani
Alshad S. Lalani
VP - Translational Sciences, Zymeworks Inc.
Verified email at zymeworks.com
Title
Cited by
Cited by
Year
HER kinase inhibition in patients with HER2-and HER3-mutant cancers
DM Hyman, SA Piha-Paul, H Won, J Rodon, C Saura, GI Shapiro, D Juric, ...
Nature 554 (7691), 189-194, 2018
6812018
Inhibition of lymphogenous metastasis using adeno-associated virus-mediated gene transfer of a soluble VEGFR-3 decoy receptor
JM Lin, AS Lalani, TC Harding, M Gonzalez, WW Wu, B Luan, GH Tu, ...
Cancer research 65 (15), 6901-6909, 2005
3382005
The T1/35kDa family of poxvirus-secreted proteins bind chemokines and modulate leukocyte influx into virus-infected tissues
KA Graham, AS Lalani, JL Macen, TL Ness, M Barry, LY Liu, A Lucas, ...
Virology 229 (1), 12-24, 1997
2721997
Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF–secreting cancer immunotherapy
B Li, AS Lalani, TC Harding, B Luan, K Koprivnikar, G Huan Tu, R Prell, ...
Clinical Cancer Research 12 (22), 6808-6816, 2006
2662006
Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition
C Daly, A Eichten, C Castanaro, E Pasnikowski, A Adler, AS Lalani, ...
Cancer research 73 (1), 108-118, 2013
2472013
The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines
AS Lalani, K Graham, K Mossman, K Rajarathnam, I Clark-Lewis, ...
Journal of virology 71 (6), 4356-4363, 1997
2261997
Neratinib Efficacy and Circulating Tumor DNA Detection of HER2 Mutations in HER2 Nonamplified Metastatic Breast Cancer
CX Ma, R Bose, F Gao, RA Freedman, ML Telli, G Kimmick, E Winer, ...
Clinical Cancer Research 23 (19), 5687-5695, 2017
2002017
Use of chemokine receptors by poxviruses
AS Lalani, J Masters, W Zeng, J Barrett, R Pannu, H Everett, CW Arendt, ...
Science 286 (5446), 1968-1971, 1999
1941999
HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers
BT Li, F Michelini, S Misale, E Cocco, L Baldino, Y Cai, S Shifman, HY Tu, ...
Cancer discovery 10 (5), 674-687, 2020
1802020
Immunomodulation by viruses: the myxoma virus story
P Nash, J Barrett, JX Cao, S Hota‐Mitchell, AS Lalani, H Everett, XM Xu, ...
Immunological reviews 168 (1), 103-120, 1999
1721999
Modulating chemokines: more lessons from viruses
AS Lalani, JW Barrett, G McFadden
Immunology today 21 (2), 100-106, 2000
1672000
Hypoxia-selective targeting by the bioreductive prodrug AQ4N in patients with solid tumors: results of a phase I study
MR Albertella, PM Loadman, PH Jones, RM Phillips, R Rampling, ...
Clinical cancer research 14 (4), 1096-1104, 2008
1512008
C‐reactive protein as a prognostic marker for men with androgen‐independent prostate cancer: results from the ASCENT trial
TM Beer, AS Lalani, S Lee, M Mori, KM Eilers, JG Curd, WD Henner, ...
Cancer: Interdisciplinary International Journal of the American Cancer …, 2008
1222008
The viral anti-inflammatory chemokine-binding protein M-T7 reduces intimal hyperplasia after vascular injury
L Liu, A Lalani, E Dai, B Seet, C Macauley, R Singh, L Fan, G McFadden, ...
The Journal of clinical investigation 105 (11), 1613-1621, 2000
1172000
Interruption of cytokine networks by poxviruses: lessons from myxoma virus
G McFadden, K Graham, K Ellison, M Barry, J Macen, M Schreiber, ...
Journal of leukocyte biology 57 (5), 731-738, 1995
1121995
Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer
LM Smyth, SA Piha-Paul, HH Won, AM Schram, C Saura, S Loi, J Lu, ...
Cancer discovery 10 (2), 198-213, 2020
1082020
Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2+ve breast cancer metastasis
A Nagpal, RP Redvers, X Ling, S Ayton, M Fuentes, E Tavancheh, I Diala, ...
Breast Cancer Research 21, 1-19, 2019
1082019
Combined Blockade of Activating ERBB2 Mutations and ER Results in Synthetic Lethality of ER+/HER2 Mutant Breast Cancer
S Croessmann, L Formisano, LN Kinch, PI Gonzalez-Ericsson, ...
Clinical Cancer Research 25 (1), 277-289, 2019
1072019
An Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant–Driven Breast Cancer
AB Hanker, MR Brewer, JH Sheehan, JP Koch, GR Sliwoski, R Nagy, ...
Cancer discovery 7 (6), 575-585, 2017
1002017
Role of the myxoma virus soluble CC-chemokine inhibitor glycoprotein, M-T1, during myxoma virus pathogenesis
AS Lalani, J Masters, K Graham, L Liu, A Lucas, G McFadden
Virology 256 (2), 233-245, 1999
961999
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