Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7 MS Minett, V Pereira, S Sikandar, A Matsuyama, S Lolignier, ... Nature communications 6 (1), 8967, 2015 | 197 | 2015 |
Pain without nociceptors? Nav1. 7-independent pain mechanisms MS Minett, S Falk, S Santana-Varela, YD Bogdanov, MA Nassar, ... Cell reports 6 (2), 301-312, 2014 | 177 | 2014 |
Brain-derived neurotrophic factor derived from sensory neurons plays a critical role in chronic pain S Sikandar, MS Minett, Q Millet, S Santana-Varela, J Lau, JN Wood, ... Brain 141 (4), 1028-1039, 2018 | 144 | 2018 |
Pain without nociceptors MS Minett, S Falk, S Santana-Varela, YD Bogdanov, MA Nassar, ... Nav1 7, 301-312, 2014 | 79 | 2014 |
Cold sensing by NaV1.8-positive and NaV1.8-negative sensory neurons AP Luiz, DI MacDonald, S Santana-Varela, Q Millet, S Sikandar, JN Wood, ... Proceedings of the National Academy of Sciences 116 (9), 3811-3816, 2019 | 62 | 2019 |
A novel human pain insensitivity disorder caused by a point mutation in ZFHX2 AM Habib, A Matsuyama, AL Okorokov, S Santana-Varela, JT Bras, ... Brain 141 (2), 365-376, 2018 | 43 | 2018 |
The Role of Nav1.9 Channel in the Development of Neuropathic Orofacial Pain Associated with Trigeminal Neuralgia AP Lulz, O Kopach, S Santana-Varela, JN Wood Molecular Pain 11, s12990-015-0076-4, 2015 | 42 | 2015 |
Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions MA Bangash, SRA Alles, S Santana-Varela, Q Millet, S Sikandar, ... Wellcome open research 3, 2018 | 40 | 2018 |
Sensory neuron–derived NaV1.7 contributes to dorsal horn neuron excitability SRA Alles, F Nascimento, R Luján, AP Luiz, Q Millet, MA Bangash, ... Science Advances 6 (8), eaax4568, 2020 | 25 | 2020 |
Noninvasive mechanical joint loading as an alternative model for osteoarthritic pain F Ter Heegde, AP Luiz, S Santana‐Varela, IP Chessell, F Welsh, ... Arthritis & Rheumatology 71 (7), 1078-1088, 2019 | 25 | 2019 |
Osteoarthritis-related nociceptive behaviour following mechanical joint loading correlates with cartilage damage F Ter Heegde, AP Luiz, S Santana-Varela, R Magnúsdóttir, M Hopkinson, ... Osteoarthritis and Cartilage 28 (3), 383-395, 2020 | 21 | 2020 |
MicroRNA-1-associated effects of neuron-specific brain-derived neurotrophic factor gene deletion in dorsal root ganglia E Neumann, T Brandenburger, S Santana-Varela, R Deenen, K Köhrer, ... Molecular and Cellular Neuroscience 75, 36-43, 2016 | 19 | 2016 |
Inhibition of somatosensory mechanotransduction by annexin A6 R Raouf, S Lolignier, JE Sexton, Q Millet, S Santana-Varela, A Biller, ... Science signaling 11 (535), eaao2060, 2018 | 17 | 2018 |
Tools for analysis and conditional deletion of subsets of sensory neurons S Santana-Varela, YD Bogdanov, SJ Gossage, AL Okorokov, S Li, ... Wellcome Open Research 6, 2021 | 8 | 2021 |
Sensitization of cutaneous primary afferents in bone cancer revealed by in vivo calcium imaging L de Clauser, AP Luiz, S Santana-Varela, JN Wood, S Sikandar Cancers 12 (12), 3491, 2020 | 7 | 2020 |
Physiologic osteoclasts are not sufficient to induce skeletal pain in mice L De Clauser, S Santana‐Varela, JN Wood, S Sikandar European Journal of Pain 25 (1), 199-212, 2021 | 6 | 2021 |
Molecular basis of FAAH-OUT-associated human pain insensitivity H Mikaeili, AM Habib, CWL Yeung, S Santana-Varela, AP Luiz, ... Brain 146 (9), 3851-3865, 2023 | 2 | 2023 |
Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes A Bangash, C Cubuk, F Iseppon, R Haroun, AP Luiz, M Arcangeletti, ... bioRxiv, 2024.01. 11.575033, 2024 | | 2024 |
Genetic approaches to understanding pain mechanisms: Zfhx2 and peripheral sensory neuron ablation mouse transgenic models S Santana Varela UCL (University College London), 2022 | | 2022 |
Non-invasive murine joint loading model: a novel model for osteoarthritic pain F ter Heegde, AP Luiz, S Santana-Varela, JN Wood, C Chenu Osteoarthritis and Cartilage 26, S356, 2018 | | 2018 |