Steffen Renner
Steffen Renner
Investigator at Novartis
Verified email at novartis.com
Title
Cited by
Cited by
Year
Small-molecule inhibition of APT1 affects Ras localization and signaling
FJ Dekker, O Rocks, N Vartak, S Menninger, C Hedberg, R Balamurugan, ...
Nature chemical biology 6 (6), 449, 2010
2992010
Interactive exploration of chemical space with Scaffold Hunter
S Wetzel, K Klein, S Renner, D Rauh, TI Oprea, P Mutzel, H Waldmann
Nature chemical biology 5 (8), 581-583, 2009
2102009
Natural-product-derived fragments for fragment-based ligand discovery
B Over, S Wetzel, C Grütter, Y Nakai, S Renner, D Rauh, H Waldmann
Nature chemistry 5 (1), 21-28, 2013
2052013
Scaffold‐hopping: how far can you jump?
G Schneider, P Schneider, S Renner
Qsar & Combinatorial Science 25 (12), 1162-1171, 2006
1372006
Bioactivity-guided mapping and navigation of chemical space
S Renner, WAL Van Otterlo, MD Seoane, S Möcklinghoff, B Hofmann, ...
Nature chemical biology 5 (8), 585-592, 2009
1222009
Comparison of correlation vector methods for ligand-based similarity searching
U Fechner, L Franke, S Renner, P Schneider, G Schneider
Journal of computer-aided molecular design 17 (10), 687-698, 2003
1132003
Scaffold‐hopping potential of ligand‐based similarity concepts
S Renner, G Schneider
ChemMedChem: Chemistry Enabling Drug Discovery 1 (2), 181-185, 2006
1032006
Total synthesis of chondramide C and its binding mode to F‐actin
H Waldmann, TS Hu, S Renner, S Menninger, R Tannert, T Oda, HD Arndt
Angewandte Chemie International Edition 47 (34), 6473-6477, 2008
802008
A Collection of Robust Organic Synthesis Reactions for In Silico Molecule Design
M Hartenfeller, M Eberle, P Meier, C Nieto-Oberhuber, KH Altmann, ...
Journal of chemical information and modeling 51 (12), 3093-3098, 2011
702011
Homology model-based virtual screening for GPCR ligands using docking and target-biased scoring
T Weil, S Renner
Journal of chemical information and modeling 48 (5), 1104-1117, 2008
692008
Fuzzy pharmacophore models from molecular alignments for correlation-vector-based virtual screening
S Renner, G Schneider
Journal of medicinal chemistry 47 (19), 4653-4664, 2004
672004
Development of highly potent inhibitors of the Ras‐targeting human acyl protein thioesterases based on substrate similarity design
C Hedberg, FJ Dekker, M Rusch, S Renner, S Wetzel, N Vartak, ...
Angewandte Chemie International Edition 50 (42), 9832-9837, 2011
652011
Mining for bioactive scaffolds with scaffold networks: improved compound set enrichment from primary screening data
T Varin, A Schuffenhauer, P Ertl, S Renner
Journal of chemical information and modeling 51 (7), 1528-1538, 2011
652011
Positive and negative modulation of group I metabotropic glutamate receptors
M Vanejevs, C Jatzke, S Renner, S Müller, M Hechenberger, T Bauer, ...
Journal of medicinal chemistry 51 (3), 634-647, 2008
602008
Recent trends and observations in the design of high-quality screening collections
S Renner, M Popov, A Schuffenhauer, HJ Roth, W Breitenstein, ...
Future medicinal chemistry 3 (6), 751-766, 2011
542011
Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis
IV Magedov, L Frolova, M Manpadi, U Bhoga, H Tang, NM Evdokimov, ...
Journal of medicinal chemistry 54 (12), 4234-4246, 2011
532011
Impact of conformational flexibility on three-dimensional similarity searching using correlation vectors
S Renner, CH Schwab, J Gasteiger, G Schneider
Journal of chemical information and modeling 46 (6), 2324-2332, 2006
532006
A Scaffold‐Tree‐Merging Strategy for Prospective Bioactivity Annotation of γ‐Pyrones
S Wetzel, W Wilk, S Chammaa, B Sperl, AG Roth, A Yektaoglu, S Renner, ...
Angewandte Chemie 122 (21), 3748-3752, 2010
482010
Maximum common binding modes (MCBM): consensus docking scoring using multiple ligand information and interaction fingerprints
S Renner, S Derksen, S Radestock, F Mörchen
Journal of chemical information and modeling 48 (2), 319-332, 2008
482008
New inhibitors of the Tat–TAR RNA interaction found with a “fuzzy” pharmacophore model
S Renner, V Ludwig, O Boden, U Scheffer, M Göbel, G Schneider
ChemBioChem 6 (6), 1119-1125, 2005
412005
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Articles 1–20