| Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium … L Encinas, H O’Keefe, M Neu, MJ Remuiñán, AM Patel, A Guardia, ... Journal of Medicinal Chemistry 57 (4), 1276-1288, 2014 | 121 | 2014 |
| An improved one-pot method for the stereoselective synthesis of the (2S, 3R)-3-amino-2-hydroxy acids: Key intermediates for bestatin and amastatin R Herranz, J Castro-Pichel, S Vinuesa, MT Garcia-Lopez The Journal of Organic Chemistry 55 (7), 2232-2234, 1990 | 88 | 1990 |
| Synthesis of 6‐, 7‐and 8‐Carbon Sugar Analogues of Potent Anti‐Influenza 2, 3‐Didehydro‐2, 3‐dideoxy‐N‐acetylneuraminic Acid Derivatives. MJ Bamford, JC Pichel, W Husman, B Patel, R Storer, NG Weir ChemInform 26 (36), no-no, 1995 | 71 | 1995 |
| Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor M Martínez-Hoyos, E Perez-Herran, G Gulten, L Encinas, ... EBioMedicine 8, 291-301, 2016 | 66 | 2016 |
| Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase SM Batt, M Cacho Izquierdo, J Castro Pichel, CJ Stubbs, ... ACS Infectious Diseases 1 (12), 615-626, 2015 | 65 | 2015 |
| A facile synthesis of ascamycin and related analogues J Castro-Pichel, MT García-López, G Federico Tetrahedron 43 (2), 383-389, 1987 | 50 | 1987 |
| Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery MJ Rebollo-Lopez, J Lelièvre, D Alvarez-Gomez, J Castro-Pichel, ... PloS one 10 (12), e0142293, 2015 | 46 | 2015 |
| New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold S Pajk, M Živec, R Šink, I Sosič, M Neu, C Chung, M Martínez-Hoyos, ... European Journal of Medicinal Chemistry 112, 252-257, 2016 | 42 | 2016 |
| Cyclopropyl carboxamides: a new oral antimalarial series derived from the Tres Cantos anti-malarial set (TCAMS) L Rueda, I Castellote, J Castro-Pichel, MJ Chaparro, JC de la Rosa, ... ACS Medicinal Chemistry Letters 2 (11), 840-844, 2011 | 38 | 2011 |
| Tributyltin cyanide, a novel reagent for the stereoselective preparation of 3-amino-2-hydroxy acids via cyanohydrin intermediates R Herranz, J Castro-Pichel, T García-López Synthesis 1989 (09), 703-706, 1989 | 36 | 1989 |
| N‐Benzyl‐4‐((heteroaryl)methyl)benzamides: A New Class of Direct NADH‐Dependent 2‐trans Enoyl–Acyl Carrier Protein Reductase (InhA) Inhibitors with … A Guardia, G Gulten, R Fernandez, J Gómez, F Wang, M Convery, ... ChemMedChem 11 (7), 687-701, 2016 | 30 | 2016 |
| Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase Inhibitors: Expeditious Reconstruction of Suboptimal Hits into a Series with Potent in Vivo … JA Borthwick, C Alemparte, I Wall, BC Whitehurst, A Argyrou, G Burley, ... Journal of Medicinal Chemistry 63 (5), 2557-2576, 2020 | 25 | 2020 |
| 4‐Substituted Thioquinolines and Thiazoloquinolines: Potent, Selective, and Tween‐80 in vitro Dependent Families of Antitubercular Agents with Moderate in vivo Activity J Escribano, C Rivero‐Hernández, H Rivera, D Barros, J Castro‐Pichel, ... ChemMedChem 6 (12), 2252-2263, 2011 | 22 | 2011 |
| Antifungal sordaridin derivatives JRR Gomez, JMB Calderon, SGO Dorado, MTF Gabaldon, JC Pichel, ... US Patent 5,854,280, 1998 | 20 | 1998 |
| Aminodeoxybestatin and epi-aminodeoxybestatin: stereospecific synthesis and aminopeptidase inhibition R Herranz, S Vinuesa, J Castro-Pichel, C Pérez, MT García-López Journal of the Chemical Society, Perkin Transactions 1, 1825-1830, 1992 | 17 | 1992 |
| 3-Amino-pyrazole derivatives useful against tuberculosis JC Pichel, RF Menendez, EPF Velando, SG Del Valle, A Mallo-Rubio | 12 | 2012 |
| Photoredox-Catalyzed Radical Relay Reaction Toward Functionalized Vicinal Diamines XD An, S Yu Synthesis 50 (17), 3387-3394, 2018 | 10 | 2018 |
| 1, 3, 4-thiadiazole-2-amine and (Pyrazol-3-yl)-1, 3, 4-thiazole-2-amine Compounds L Ballell Pages, J Castro Pichel, R Fernandez Menendez, ... PCT publication No. WO 118852, A1, 2010 | 10 | 2010 |
| Stereoselection in the synthesis of threo-and erythro-3-amino-2-hydroxy-4-phenyl-butanoic acid using chiral acetal templates R Herranz, J Castro-Pichel, S Vinuesa, MT García-López Journal of the Chemical Society, Chemical Communications, 938-939, 1989 | 10 | 1989 |
| Tetrahydropyrazolo [1, 5-A] pyrimidine as anti-tuberculosis compounds E Alvarez-Ruiz, L Ballell-Pages, JC Pichel, L Encinas, J Esquivias, ... US Patent App. 14/112,564, 2014 | 8 | 2014 |
