| Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease C Zuccato, A Ciammola, D Rigamonti, BR Leavitt, D Goffredo, L Conti, ... Science 293 (5529), 493-498, 2001 | 1596 | 2001 |
| Wild-type huntingtin protects from apoptosis upstream of caspase-3 D Rigamonti, JH Bauer, C De-Fraja, L Conti, S Sipione, C Sciorati, ... Journal of Neuroscience 20 (10), 3705-3713, 2000 | 545 | 2000 |
| Loss of normal huntingtin function: new developments in Huntington's disease research E Cattaneo, D Rigamonti, D Goffredo, C Zuccato, F Squitieri, S Sipione Trends in neurosciences 24 (3), 182-188, 2001 | 491 | 2001 |
| Sphingolipids and gangliosides of the nervous system in membrane function and dysfunction EP de Chaves, S Sipione FEBS letters 584 (9), 1748-1759, 2010 | 312 | 2010 |
| Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease M Valenza, D Rigamonti, D Goffredo, C Zuccato, S Fenu, L Jamot, ... Journal of Neuroscience 25 (43), 9932-9939, 2005 | 310 | 2005 |
| Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses S Sipione, D Rigamonti, M Valenza, C Zuccato, L Conti, J Pritchard, ... Human molecular genetics 11 (17), 1953-1965, 2002 | 300 | 2002 |
| Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing D Rigamonti, S Sipione, D Goffredo, C Zuccato, E Fossale, E Cattaneo Journal of Biological Chemistry 276 (18), 14545-14548, 2001 | 254 | 2001 |
| Insulin expressing cells from differentiated embryonic stem cells are not beta cells S Sipione, A Eshpeter, JG Lyon, GS Korbutt, RC Bleackley Diabetologia 47, 499-508, 2004 | 251 | 2004 |
| Kinase inhibitors modulate huntingtin cell localization and toxicity RS Atwal, CR Desmond, N Caron, T Maiuri, J Xia, S Sipione, R Truant Nature chemical biology 7 (7), 453-460, 2011 | 207 | 2011 |
| Gangliosides in the brain: physiology, pathophysiology and therapeutic applications S Sipione, J Monyror, D Galleguillos, N Steinberg, V Kadam Frontiers in neuroscience 14, 572965, 2020 | 189 | 2020 |
| Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice A Di Pardo, V Maglione, M Alpaugh, M Horkey, RS Atwal, J Sassone, ... Proceedings of the National Academy of Sciences 109 (9), 3528-3533, 2012 | 177 | 2012 |
| Impaired ganglioside metabolism in Huntington's disease and neuroprotective role of GM1 V Maglione, P Marchi, A Di Pardo, S Lingrell, M Horkey, E Tidmarsh, ... Journal of Neuroscience 30 (11), 4072-4080, 2010 | 150 | 2010 |
| Shc signaling in differentiating neural progenitor cells L Conti, S Sipione, L Magrassi, L Bonfanti, D Rigamonti, V Pettirossi, ... Nature neuroscience 4 (6), 579-586, 2001 | 150 | 2001 |
| Transplantation of prodrug-converting neural progenitor cells for brain tumor therapy V Barresi, N Belluardo, S Sipione, G Mudó, E Cattaneo, DF Condorelli Cancer gene therapy 10 (5), 396-402, 2003 | 131 | 2003 |
| Identification of a novel human granzyme B inhibitor secreted by cultured sertoli cells S Sipione, KC Simmen, SJ Lord, B Motyka, C Ewen, I Shostak, GR Rayat, ... The Journal of Immunology 177 (8), 5051-5058, 2006 | 114 | 2006 |
| Gangliosides: treatment avenues in neurodegenerative disease PJ Magistretti, FH Geisler, JS Schneider, PA Li, H Fiumelli, S Sipione Frontiers in neurology 10, 472101, 2019 | 105 | 2019 |
| Modeling Huntington’s disease in cells, flies, and mice S Sipione, E Cattaneo Molecular neurobiology 23, 21-51, 2001 | 105 | 2001 |
| Aberrant amplification of A2A receptor signaling in striatal cells expressing mutant huntingtin K Varani, D Rigamonti, S Sipione, A Camurri, PA Borea, F Cattabeni, ... The FASEB Journal 15 (7), 1245-1247, 2001 | 104 | 2001 |
| SUMOylation regulates Kv2. 1 and modulates pancreatic β-cell excitability XQ Dai, J Kolic, P Marchi, S Sipione, PE MacDonald Journal of cell science 122 (6), 775-779, 2009 | 103 | 2009 |
| The cloning and expression of a murine triacylglycerol hydrolase cDNA and the structure of its corresponding gene VW Dolinsky, S Sipione, R Lehner, DE Vance Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2001 | 100 | 2001 |
