| Molecular signatures of G-protein-coupled receptors AJ Venkatakrishnan, X Deupi, G Lebon, CG Tate, GF Schertler, MM Babu Nature 494 (7436), 185-194, 2013 | 1610 | 2013 |
| Conformational complexity of G-protein-coupled receptors BK Kobilka, X Deupi Trends in pharmacological sciences 28 (8), 397-406, 2007 | 862 | 2007 |
| Coupling ligand structure to specific conformational switches in the β2-adrenoceptor X Yao, C Parnot, X Deupi, VRP Ratnala, G Swaminath, D Farrens, ... Nature chemical biology 2 (8), 417-422, 2006 | 413 | 2006 |
| Probing the β2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists G Swaminath, X Deupi, TW Lee, W Zhu, FS Thian, TS Kobilka, B Kobilka Journal of Biological Chemistry 280 (23), 22165-22171, 2005 | 323 | 2005 |
| Energy landscapes as a tool to integrate GPCR structure, dynamics, and function X Deupi, BK Kobilka Physiology 25 (5), 293-303, 2010 | 313 | 2010 |
| Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region AJ Venkatakrishnan, X Deupi, G Lebon, FM Heydenreich, T Flock, ... Nature 536 (7617), 484-487, 2016 | 295 | 2016 |
| The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex XJ Yao, G Vélez Ruiz, MR Whorton, SGF Rasmussen, BT DeVree, ... Proceedings of the National Academy of Sciences 106 (23), 9501-9506, 2009 | 278 | 2009 |
| Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II X Deupi, P Edwards, A Singhal, B Nickle, D Oprian, G Schertler, ... Proceedings of the National Academy of Sciences 109 (1), 119-124, 2012 | 276 | 2012 |
| Structural insights into agonist-induced activation of G-protein-coupled receptors X Deupi, J Standfuss Current opinion in structural biology 21 (4), 541-551, 2011 | 265 | 2011 |
| Tracking G-protein-coupled receptor activation using genetically encoded infrared probes S Ye, E Zaitseva, G Caltabiano, GFX Schertler, TP Sakmar, X Deupi, ... Nature 464 (7293), 1386-1389, 2010 | 264 | 2010 |
| Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer JJ Fung, X Deupi, L Pardo, XJ Yao, GA Velez-Ruiz, BT DeVree, ... The EMBO journal 28 (21), 3315-3328, 2009 | 216 | 2009 |
| Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy R Rahmeh, M Damian, M Cottet, H Orcel, C Mendre, T Durroux, ... Proceedings of the National Academy of Sciences 109 (17), 6733-6738, 2012 | 213 | 2012 |
| Serine and Threonine Residues Bend α-Helices in the chi1 = g- Conformation JA Ballesteros, X Deupi, M Olivella, EEJ Haaksma, L Pardo Biophysical journal 79 (5), 2754-2760, 2000 | 205 | 2000 |
| Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor S Isogai, X Deupi, C Opitz, FM Heydenreich, CJ Tsai, F Brueckner, ... Nature 530 (7589), 237-241, 2016 | 190 | 2016 |
| The TXP Motif in the Second Transmembrane Helix of CCR5 A STRUCTURAL DETERMINANT OF CHEMOKINE-INDUCED ACTIVATION C Govaerts, C Blanpain, X Deupi, S Ballet, JA Ballesteros, SJ Wodak, ... Journal of Biological Chemistry 276 (16), 13217-13225, 2001 | 165 | 2001 |
| The Role of Internal Water Molecules in the Structure and Function of the Rhodopsin Family of G Protein‐Coupled Receptors L Pardo, X Deupi, N Dölker, ML López‐Rodríguez, M Campillo ChemBioChem 8 (1), 19-24, 2007 | 144 | 2007 |
| An activation switch in the rhodopsin family of G protein coupled receptors: the thyrotropin receptor E Urizar, S Claeysen, X Deupí, C Govaerts, S Costagliola, G Vassart, ... Journal of Biological Chemistry, 2005 | 140 | 2005 |
| Activation of G protein-coupled receptors X Deupi, B Kobilka Advances in protein chemistry 74, 137-166, 2007 | 135 | 2007 |
| An online resource for GPCR structure determination and analysis C Munk, E Mutt, V Isberg, LF Nikolajsen, JM Bibbe, T Flock, MA Hanson, ... Nature methods 16 (2), 151-162, 2019 | 117 | 2019 |
| Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3 C Govaerts, A Bondue, JY Springael, M Olivella, X Deupi, E Le Poul, ... Journal of Biological Chemistry 278 (3), 1892-1903, 2003 | 116 | 2003 |
Gebhard F. X SchertlerHead of Biology and Chemistry Devision, PSI / ETHVerified email at psi.ch
