| G3BP1 is a tunable switch that triggers phase separation to assemble stress granules P Yang, C Mathieu, RM Kolaitis, P Zhang, J Messing, U Yurtsever, Z Yang, ... Cell 181 (2), 325-345. e28, 2020 | 771 | 2020 |
| Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy J Wei, L Long, W Zheng, Y Dhungana, SA Lim, C Guy, Y Wang, YD Wang, ... Nature 576 (7787), 471-476, 2019 | 280 | 2019 |
| Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia E Piovan, J Yu, V Tosello, D Herranz, A Ambesi-Impiombato, AC Da Silva, ... Cancer cell 24 (6), 766-776, 2013 | 279 | 2013 |
| Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells X Du, J Wen, Y Wang, PWF Karmaus, A Khatamian, H Tan, Y Li, C Guy, ... Nature 558 (7708), 141-145, 2018 | 163 | 2018 |
| Cross-cohort analysis identifies a TEAD4–MYCN positive feedback loop as the core regulatory element of high-risk neuroblastoma P Rajbhandari, G Lopez, C Capdevila, B Salvatori, J Yu, ... Cancer discovery 8 (5), 582-599, 2018 | 128 | 2018 |
| Inhibition of the autocrine IL-6–JAK2–STAT3–calprotectin axis as targeted therapy for HR−/HER2+ breast cancers R Rodriguez-Barrueco, J Yu, LP Saucedo-Cuevas, M Olivan, ... Genes & development 29 (15), 1631-1648, 2015 | 124 | 2015 |
| Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells H Cheng, Z Zhang, R Rodriguez-Barrueco, A Borczuk, H Liu, J Yu, ... Oncotarget 7 (20), 28976, 2016 | 99 | 2016 |
| miR-424 (322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy R Rodriguez-Barrueco, EA Nekritz, F Bertucci, J Yu, F Sanchez-Garcia, ... Genes & development 31 (6), 553-566, 2017 | 96 | 2017 |
| Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia Y Gocho, J Liu, J Hu, W Yang, NV Dharia, J Zhang, H Shi, G Du, A John, ... Nature cancer 2 (3), 284-299, 2021 | 86 | 2021 |
| In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions H Huang, P Zhou, J Wei, L Long, H Shi, Y Dhungana, NM Chapman, G Fu, ... Cell 184 (5), 1245-1261. e21, 2021 | 74 | 2021 |
| Metabolic control of TFH cells and humoral immunity by phosphatidylethanolamine G Fu, CS Guy, NM Chapman, G Palacios, J Wei, P Zhou, L Long, ... Nature 595 (7869), 724-729, 2021 | 70 | 2021 |
| LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity Y Wang, X Du, J Wei, L Long, H Tan, C Guy, Y Dhungana, C Qian, ... Cell research 29 (5), 391-405, 2019 | 57 | 2019 |
| MYC is a critical target of FBXW7 M Sato, R Rodriguez-Barrueco, J Yu, C Do, JM Silva, J Gautier Oncotarget 6 (5), 3292, 2015 | 57 | 2015 |
| HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers P Putcha, J Yu, R Rodriguez-Barrueco, L Saucedo-Cuevas, P Villagrasa, ... Breast Cancer Research 17, 1-14, 2015 | 55 | 2015 |
| ScreenBEAM: a novel meta-analysis algorithm for functional genomics screens via Bayesian hierarchical modeling J Yu, J Silva, A Califano Bioinformatics 32 (2), 260-267, 2016 | 54 | 2016 |
| Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia RJ Autry, SW Paugh, R Carter, L Shi, J Liu, DC Ferguson, CE Lau, ... Nature cancer 1 (3), 329-344, 2020 | 53 | 2020 |
| CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity L Long, J Wei, SA Lim, JL Raynor, H Shi, JP Connelly, H Wang, C Guy, ... Nature 600 (7888), 308-313, 2021 | 45 | 2021 |
| SJARACNe: a scalable software tool for gene network reverse engineering from big data A Khatamian, EO Paull, A Califano, J Yu Bioinformatics 35 (12), 2165-2166, 2019 | 43 | 2019 |
| Systems immunology: Integrating multi-omics data to infer regulatory networks and hidden drivers of immunity J Yu, J Peng, H Chi Current opinion in systems biology 15, 19-29, 2019 | 32 | 2019 |
| The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma AG Patel, X Chen, X Huang, MR Clay, NL Komarova, MJ Krasin, A Pappo, ... Developmental cell 57 (10), 1226-1240. e8, 2022 | 30 | 2022 |
Qingfei PanSt. Jude Children's Research HospitalVerified email at stjude.org
