| Formation of new chromatin domains determines pathogenicity of genomic duplications M Franke, DM Ibrahim, G Andrey, W Schwarzer, V Heinrich, R Schöpflin, ... Nature 538 (7624), 265-269, 2016 | 737 | 2016 |
| Functional dissection of the Sox9–Kcnj2 locus identifies nonessential and instructive roles of TAD architecture A Despang, R Schöpflin, M Franke, S Ali, I Jerković, C Paliou, WL Chan, ... Nature genetics 51 (8), 1263-1271, 2019 | 310 | 2019 |
| Deletions, inversions, duplications: engineering of structural variants using CRISPR/Cas in mice K Kraft, S Geuer, AJ Will, WL Chan, C Paliou, M Borschiwer, I Harabula, ... Cell reports 10 (5), 833-839, 2015 | 259 | 2015 |
| Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis BK Kragesteen, M Spielmann, C Paliou, V Heinrich, R Schöpflin, ... Nature genetics 50 (10), 1463-1473, 2018 | 195 | 2018 |
| Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog) AJ Will, G Cova, M Osterwalder, WL Chan, L Wittler, N Brieske, V Heinrich, ... Nature Genetics 49 (10), 1539-1545, 2017 | 126 | 2017 |
| Secretion of beta-propeller phytase from tobacco and Arabidopsis roots enhances phosphorus utilization SC Lung, WL Chan, W Yip, L Wang, EC Yeung, BL Lim Plant science 169 (2), 341-349, 2005 | 111 | 2005 |
| Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator L Allou, S Balzano, A Magg, M Quinodoz, B Royer-Bertrand, R Schöpflin, ... Nature 592 (7852), 93-98, 2021 | 106 | 2021 |
| Transport activity and presence of ClC‐7/Ostm1 complex account for different cellular functions S Weinert, S Jabs, S Hohensee, WL Chan, U Kornak, TJ Jentsch EMBO reports 15 (7), 784-791, 2014 | 67 | 2014 |
| Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice M Spielmann, N Kakar, N Tayebi, C Leettola, G Nürnberg, N Sowada, ... Genome research 26 (2), 183-191, 2016 | 66 | 2016 |
| Impaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia … WL Chan, M Steiner, T Witkos, J Egerer, B Busse, S Mizumoto, JM Pestka, ... PLoS Genetics 14 (3), e1007242, 2018 | 58 | 2018 |
| GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation TM Witkos, WL Chan, M Joensuu, M Rhiel, E Pallister, J Thomas-Oates, ... Nature Communications 10 (1), 127, 2019 | 54 | 2019 |
| GORAB missense mutations disrupt RAB6 and ARF5 binding and golgi targeting J Egerer, D Emmerich, B Fischer-Zirnsak, WL Chan, D Meierhofer, ... Journal of Investigative Dermatology 135 (10), 2368-2376, 2015 | 40 | 2015 |
| Examining tissue composition, whole-bone morphology and mechanical behavior of GorabPrx1 mice tibiae: A mouse model of premature aging H Yang, L Albiol, WL Chan, D Wulsten, A Seliger, M Thelen, T Thiele, ... Journal of biomechanics 65, 145-153, 2017 | 27 | 2017 |
| Properties of beta-propeller phytase expressed in transgenic tobacco WL Chan, SC Lung, BL Lim Protein expression and purification 46 (1), 100-106, 2006 | 24 | 2006 |
| Single-cell, whole-embryo phenotyping of mammalian developmental disorders X Huang, J Henck, C Qiu, VKA Sreenivasan, S Balachandran, OV Amarie, ... Nature 623 (7988), 772-781, 2023 | 18 | 2023 |
| Functional dissection of TADs reveals non-essential and instructive roles in regulating gene expression A Despang, R Schöpflin, M Franke, S Ali, I Jerkovic, C Paliou, WL Chan, ... bioRxiv, 566562, 2019 | 13 | 2019 |
| Single cell, whole embryo phenotyping of pleiotropic disorders of mammalian development X Huang, J Henck, C Qiu, VKA Sreenivasan, S Balachandran, R Behncke, ... bioRxiv, 2022.08. 03.500325, 2022 | 4 | 2022 |
| Altered bone formation response to mechanical loading in a mouse model of the progeroid disorder gerodermia osteodysplastica H Yang, A Seliger, M Thelen, WL Chan, U Kornak, BM Willie Orthopaedic Research Society, 2015 | 1 | 2015 |
| Targeting TGF‐β signaling, oxidative stress, and cellular senescence rescues osteoporosis in gerodermia osteodysplastica WL Chan, CH Bucher, J Goldes, AC Ma, M Steiner, BM Willie, S Mundlos, ... Aging Cell 23 (12), e14322, 2024 | | 2024 |
| Enhancer adoption by an LTR retrotransposon generates viral-like particles causing developmental limb phenotypes J Glaser, G Cova, B Fauler, CA Prada-Medina, V Stanislas, MHQ Phan, ... bioRxiv, 2024.09. 13.612906, 2024 | | 2024 |
