Michael O. Hottiger
Michael O. Hottiger
Verified email at dmmd.uzh.ch
TitleCited byYear
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
R Mostoslavsky, KF Chua, DB Lombard, WW Pang, MR Fischer, L Gellon, ...
Cell 124 (2), 315-329, 2006
p53 inhibition by the LANA protein of KSHV protects against cell death
J Friborg, W Kong, MO Hottiger, GJ Nabel
Nature 402 (6764), 889-894, 1999
Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?
PO Hassa, SS Haenni, M Elser, MO Hottiger
Microbiol. Mol. Biol. Rev. 70 (3), 789-829, 2006
Toward a unified nomenclature for mammalian ADP-ribosyltransferases
MO Hottiger, PO Hassa, B Lüscher, H Schüler, F Koch-Nolte
Trends in biochemical sciences 35 (4), 208-219, 2010
The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases
PO Hassa, MO Hottiger
Front Biosci 13 (13), 3046-3082, 2008
The functional role of poly (ADP-ribose) polymerase 1 as novel coactivator of NF-κB in inflammatory disorders
PO Hassa, MO Hottiger
Cellular and Molecular Life Sciences CMLS 59 (9), 1534-1553, 2002
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation
G Timinszky, S Till, PO Hassa, M Hothorn, G Kustatscher, B Nijmeijer, ...
Nature structural & molecular biology 16 (9), 923, 2009
A role of poly (ADP-ribose) polymerase in NF-B transcriptional activation
PO Hassa, MO Hottiger
Biological chemistry 380 (7-8), 953-959, 1999
The enzymatic and DNA binding activity of PARP-1 are not required for NF-κB coactivator function
PO Hassa, M Covic, S Hasan, R Imhof, MO Hottiger
Journal of Biological Chemistry 276 (49), 45588-45597, 2001
Molecular mechanism of poly (ADP-ribosyl) ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites
M Altmeyer, S Messner, PO Hassa, M Fey, MO Hottiger
Nucleic acids research 37 (11), 3723-3738, 2009
Poly (ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding
G Asher, H Reinke, M Altmeyer, M Gutierrez-Arcelus, MO Hottiger, ...
Cell 142 (6), 943-953, 2010
Acetylation of poly (ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-κB-dependent transcription
PO Hassa, SS Haenni, C Buerki, NI Meier, WS Lane, H Owen, ...
Journal of biological chemistry 280 (49), 40450-40464, 2005
SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310
KM Rothgiesser, S Erener, S Waibel, B Lüscher, MO Hottiger
Journal of cell science 123 (24), 4251-4258, 2010
Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation
H Kleine, E Poreba, K Lesniewicz, PO Hassa, MO Hottiger, DW Litchfield, ...
Molecular cell 32 (1), 57-69, 2008
SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly (ADP-ribose) polymerase 1
SB Rajamohan, VB Pillai, M Gupta, NR Sundaresan, KG Birukov, ...
Molecular and cellular biology 29 (15), 4116-4129, 2009
Transcriptional coactivation of nuclear factor-κB-dependent gene expression by p300 is regulated by poly (ADP)-ribose polymerase-1
PO Hassa, C Buerki, C Lombardi, R Imhof, MO Hottiger
Journal of Biological Chemistry 278 (46), 45145-45153, 2003
Arginine methyltransferase CARM1 is a promoter‐specific regulator of NF‐κB‐dependent gene expression
M Covic, PO Hassa, S Saccani, C Buerki, NI Meier, C Lombardi, R Imhof, ...
The EMBO journal 24 (1), 85-96, 2005
Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells
IM Toller, KJ Neelsen, M Steger, ML Hartung, MO Hottiger, M Stucki, ...
Proceedings of the National Academy of Sciences 108 (36), 14944-14949, 2011
Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein
MO Hottiger, GJ Nabel
Journal of Virology 72 (10), 8252-8256, 1998
PARP1 ADP-ribosylates lysine residues of the core histone tails
S Messner, M Altmeyer, H Zhao, A Pozivil, B Roschitzki, P Gehrig, ...
Nucleic acids research 38 (19), 6350-6362, 2010
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