Structure-based programming of lymph-node targeting in molecular vaccines H Liu, KD Moynihan, Y Zheng, GL Szeto, AV Li, B Huang, DS Van Egeren, ... Nature 507 (7493), 519-522, 2014 | 889 | 2014 |
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses KD Moynihan, CF Opel, GL Szeto, A Tzeng, EF Zhu, JM Engreitz, ... Nature medicine 22 (12), 1402-1410, 2016 | 531 | 2016 |
Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants MC Hanson, MP Crespo, W Abraham, KD Moynihan, GL Szeto, SH Chen, ... The Journal of clinical investigation 125 (6), 2532-2546, 2015 | 360 | 2015 |
Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2 EF Zhu, SA Gai, CF Opel, BH Kwan, R Surana, MC Mihm, MJ Kauke, ... Cancer cell 27 (4), 489-501, 2015 | 204 | 2015 |
Cell and fluid sampling microneedle patches for monitoring skin-resident immunity A Mandal, AV Boopathy, LKW Lam, KD Moynihan, ME Welch, NR Bennett, ... Science translational medicine 10 (467), eaar2227, 2018 | 135 | 2018 |
High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry YSS Yang, PU Atukorale, KD Moynihan, A Bekdemir, K Rakhra, L Tang, ... Nature communications 8 (1), 14069, 2017 | 127 | 2017 |
Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy KL Griffiths, M Ahmed, S Das, R Gopal, W Horne, TD Connell, ... Nature communications 7 (1), 13894, 2016 | 109 | 2016 |
Roles for innate immunity in combination immunotherapies KD Moynihan, DJ Irvine Cancer research 77 (19), 5215-5221, 2017 | 102 | 2017 |
Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles YSS Yang, KD Moynihan, A Bekdemir, TM Dichwalkar, MM Noh, ... Biomaterials science 7 (1), 113-124, 2019 | 76 | 2019 |
Engineering new approaches to cancer vaccines NK Mehta, KD Moynihan, DJ Irvine Cancer immunology research 3 (8), 836-843, 2015 | 70 | 2015 |
Enhancement of peptide vaccine immunogenicity by increasing lymphatic drainage and boosting serum stability KD Moynihan, RL Holden, NK Mehta, C Wang, MR Karver, J Dinter, ... Cancer immunology research 6 (9), 1025-1038, 2018 | 61 | 2018 |
Exploiting albumin as a mucosal vaccine chaperone for robust generation of lung-resident memory T cells K Rakhra, W Abraham, C Wang, KD Moynihan, N Li, N Donahue, ... Science immunology 6 (57), eabd8003, 2021 | 55 | 2021 |
Temporally programmed CD8α+ DC activation enhances combination cancer immunotherapy A Tzeng, MJ Kauke, EF Zhu, KD Moynihan, CF Opel, NJ Yang, N Mehta, ... Cell reports 17 (10), 2503-2511, 2016 | 54 | 2016 |
Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines NK Mehta, RV Pradhan, AP Soleimany, KD Moynihan, AM Rothschilds, ... Nature biomedical engineering 4 (6), 636-648, 2020 | 51 | 2020 |
Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding LP Andrews, A Somasundaram, JM Moskovitz, AL Szymczak-Workman, ... Science immunology 5 (49), eabc2728, 2020 | 39 | 2020 |
Radiation-enhanced delivery of systemically administered amphiphilic-CpG oligodeoxynucleotide OK Appelbe, KD Moynihan, A Flor, N Rymut, DJ Irvine, SJ Kron Journal of Controlled Release 266, 248-255, 2017 | 26 | 2017 |
Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity CM Backlund, RL Holden, KD Moynihan, D Garafola, C Farquhar, ... Proceedings of the National Academy of Sciences 119 (32), e2204078119, 2022 | 24 | 2022 |
Methods of treating cancer cells expressing tumor-associated integrins KD Wittrup, DJ Irvine, CF Opel, KD Moynihan, JR Cochran, BH Kwan US Patent 10,888,603, 2021 | 15 | 2021 |
Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models A Rothschilds, A Tzeng, NK Mehta, KD Moynihan, DJ Irvine, KD Wittrup Oncoimmunology 8 (5), e1558678, 2019 | 15 | 2019 |
Combined HDAC and BET inhibition enhances melanoma vaccine immunogenicity and efficacy A Badamchi-Zadeh, KD Moynihan, RA Larocca, M Aid, NM Provine, ... The Journal of Immunology 201 (9), 2744-2752, 2018 | 14 | 2018 |