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Kelly D. Moynihan
Kelly D. Moynihan
Bestätigte E-Mail-Adresse bei mit.edu
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Structure-based programming of lymph-node targeting in molecular vaccines
H Liu, KD Moynihan, Y Zheng, GL Szeto, AV Li, B Huang, DS Van Egeren, ...
Nature 507 (7493), 519-522, 2014
8892014
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
KD Moynihan, CF Opel, GL Szeto, A Tzeng, EF Zhu, JM Engreitz, ...
Nature medicine 22 (12), 1402-1410, 2016
5312016
Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants
MC Hanson, MP Crespo, W Abraham, KD Moynihan, GL Szeto, SH Chen, ...
The Journal of clinical investigation 125 (6), 2532-2546, 2015
3602015
Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2
EF Zhu, SA Gai, CF Opel, BH Kwan, R Surana, MC Mihm, MJ Kauke, ...
Cancer cell 27 (4), 489-501, 2015
2042015
Cell and fluid sampling microneedle patches for monitoring skin-resident immunity
A Mandal, AV Boopathy, LKW Lam, KD Moynihan, ME Welch, NR Bennett, ...
Science translational medicine 10 (467), eaar2227, 2018
1352018
High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry
YSS Yang, PU Atukorale, KD Moynihan, A Bekdemir, K Rakhra, L Tang, ...
Nature communications 8 (1), 14069, 2017
1272017
Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy
KL Griffiths, M Ahmed, S Das, R Gopal, W Horne, TD Connell, ...
Nature communications 7 (1), 13894, 2016
1092016
Roles for innate immunity in combination immunotherapies
KD Moynihan, DJ Irvine
Cancer research 77 (19), 5215-5221, 2017
1022017
Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles
YSS Yang, KD Moynihan, A Bekdemir, TM Dichwalkar, MM Noh, ...
Biomaterials science 7 (1), 113-124, 2019
762019
Engineering new approaches to cancer vaccines
NK Mehta, KD Moynihan, DJ Irvine
Cancer immunology research 3 (8), 836-843, 2015
702015
Enhancement of peptide vaccine immunogenicity by increasing lymphatic drainage and boosting serum stability
KD Moynihan, RL Holden, NK Mehta, C Wang, MR Karver, J Dinter, ...
Cancer immunology research 6 (9), 1025-1038, 2018
612018
Exploiting albumin as a mucosal vaccine chaperone for robust generation of lung-resident memory T cells
K Rakhra, W Abraham, C Wang, KD Moynihan, N Li, N Donahue, ...
Science immunology 6 (57), eabd8003, 2021
552021
Temporally programmed CD8α+ DC activation enhances combination cancer immunotherapy
A Tzeng, MJ Kauke, EF Zhu, KD Moynihan, CF Opel, NJ Yang, N Mehta, ...
Cell reports 17 (10), 2503-2511, 2016
542016
Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines
NK Mehta, RV Pradhan, AP Soleimany, KD Moynihan, AM Rothschilds, ...
Nature biomedical engineering 4 (6), 636-648, 2020
512020
Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding
LP Andrews, A Somasundaram, JM Moskovitz, AL Szymczak-Workman, ...
Science immunology 5 (49), eabc2728, 2020
392020
Radiation-enhanced delivery of systemically administered amphiphilic-CpG oligodeoxynucleotide
OK Appelbe, KD Moynihan, A Flor, N Rymut, DJ Irvine, SJ Kron
Journal of Controlled Release 266, 248-255, 2017
262017
Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity
CM Backlund, RL Holden, KD Moynihan, D Garafola, C Farquhar, ...
Proceedings of the National Academy of Sciences 119 (32), e2204078119, 2022
242022
Methods of treating cancer cells expressing tumor-associated integrins
KD Wittrup, DJ Irvine, CF Opel, KD Moynihan, JR Cochran, BH Kwan
US Patent 10,888,603, 2021
152021
Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models
A Rothschilds, A Tzeng, NK Mehta, KD Moynihan, DJ Irvine, KD Wittrup
Oncoimmunology 8 (5), e1558678, 2019
152019
Combined HDAC and BET inhibition enhances melanoma vaccine immunogenicity and efficacy
A Badamchi-Zadeh, KD Moynihan, RA Larocca, M Aid, NM Provine, ...
The Journal of Immunology 201 (9), 2744-2752, 2018
142018
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