A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1 J Le Nours, NA Gherardin, SH Ramarathinam, W Awad, F Wiede, ... Science 366 (6472), 1522-1527, 2019 | 109 | 2019 |
Increased production of retinoic acid by intestinal macrophages contributes to their inflammatory phenotype in patients with Crohn's disease TJ Sanders, NE McCarthy, EM Giles, KLM Davidson, MLR Haltalli, ... Gastroenterology 146 (5), 1278-1288. e2, 2014 | 101 | 2014 |
The future is now? Clinical and translational aspects of “Omics” technologies GL D’Adamo, JT Widdop, EM Giles Immunology and cell biology 99 (2), 168-176, 2021 | 69 | 2021 |
Systemic inflammatory response syndrome after major abdominal surgery predicted by early upregulation of TLR4 and TLR5 R Lahiri, Y Derwa, Z Bashir, E Giles, HDT Torrance, HC Owen, ... Annals of surgery 263 (5), 1028-1037, 2016 | 64 | 2016 |
The future of faecal transplants EM Giles, GL D’Adamo, SC Forster Nature Reviews Microbiology 17 (12), 719-719, 2019 | 63 | 2019 |
Systematic review: MRI enterography for assessment of small bowel involvement in paediatric Crohn's disease E Giles, AR Barclay, S Chippington, DC Wilson Alimentary pharmacology & therapeutics 37 (12), 1121-1131, 2013 | 62 | 2013 |
Proinflammatory Vδ2+ T cells populate the human intestinal mucosa and enhance IFN-γ production by colonic αβ T cells NE McCarthy, Z Bashir, A Vossenkämper, CR Hedin, EM Giles, ... The Journal of Immunology 191 (5), 2752-2763, 2013 | 56 | 2013 |
Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn’s disease NE McCarthy, CR Hedin, TJ Sanders, P Amon, I Hoti, I Ayada, V Baji, ... The Journal of clinical investigation 125 (8), 3215-3225, 2015 | 55 | 2015 |
Type 1 Interferon in the human intestine—a co-ordinator of the immune response to the microbiota EM Giles, AJ Stagg Inflammatory Bowel Diseases 23 (4), 524-533, 2017 | 31 | 2017 |
Regulation of human intestinal T-cell responses by type 1 interferon-STAT1 signaling is disrupted in inflammatory bowel disease EM Giles, TJ Sanders, NE McCarthy, J Lung, M Pathak, TT MacDonald, ... Mucosal Immunology 10 (1), 184-193, 2017 | 30 | 2017 |
the future of microbiome‐based therapeutics EL Gulliver, RB Young, M Chonwerawong, GL D'Adamo, T Thomason, ... Alimentary Pharmacology & Therapeutics 56 (2), 192-208, 2022 | 26 | 2022 |
Optimal assessment of paediatric IBD with MRI and barium follow-through E Giles, O Hanci, A McLean, N Power, A Cole, NM Croft, K McDonald, ... Journal of pediatric gastroenterology and nutrition 54 (6), 758-762, 2012 | 26 | 2012 |
Recognition of the antigen-presenting molecule MR1 by a Vδ3+ γδ T cell receptor MT Rice, A von Borstel, P Chevour, W Awad, LJ Howson, DR Littler, ... Proceedings of the National Academy of Sciences 118 (49), e2110288118, 2021 | 25 | 2021 |
Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire A von Borstel, P Chevour, D Arsovski, JMM Krol, LJ Howson, AA Berry, ... Science translational medicine 13 (622), eabe7430, 2021 | 23 | 2021 |
Zinc in extremely low-birthweight or very preterm infants E Giles, LW Doyle NeoReviews 8 (4), e165-e172, 2007 | 23 | 2007 |
Clinical presentation and outcomes of diagnostic endoscopy in newly presenting children with gastrointestinal symptoms S Wang, O Younus, D Rawat, S Naik, E Giles, N Meadows, NM Croft Journal of Pediatric Gastroenterology and Nutrition 66 (6), 876-881, 2018 | 22 | 2018 |
Microbiome in health and disease EM Giles, J Couper Journal of Paediatrics and Child Health 56 (11), 1735-1738, 2020 | 16 | 2020 |
Routine coagulation screening in children undergoing gastrointestinal endoscopy does not predict those at risk of bleeding E Giles, E Walton-Salih, N Shah, R Hinds Endoscopy 38 (05), 508-510, 2006 | 16 | 2006 |
Disease-specific loss of microbial cross-feeding interactions in the human gut VR Marcelino, C Welsh, C Diener, EL Gulliver, EL Rutten, RB Young, ... Nature Communications 14 (1), 6546, 2023 | 11 | 2023 |
Impact of a new young adult inflammatory bowel disease transition clinic on patient satisfaction and clinical outcomes T Mollah, D Lee, E Giles Journal of Paediatrics and Child Health 58 (6), 1053-1059, 2022 | 9 | 2022 |