Mathew Garnett
Mathew Garnett
Wellcome Sanger Institute
Verified email at sanger.ac.uk
Title
Cited by
Cited by
Year
Mutations of the BRAF gene in human cancer
H Davies, GR Bignell, C Cox, P Stephens, S Edkins, S Clegg, J Teague, ...
Nature 417 (6892), 949-954, 2002
102602002
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
PTC Wan, MJ Garnett, SM Roe, S Lee, D Niculescu-Duvaz, VM Good, ...
Cell 116 (6), 855-867, 2004
26092004
Systematic identification of genomic markers of drug sensitivity in cancer cells
MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ...
Nature 483 (7391), 570-575, 2012
18552012
Guilty as charged: B-RAF is a human oncogene
MJ Garnett, R Marais
Cancer cell 6 (4), 313-319, 2004
9852004
Prospective derivation of a living organoid biobank of colorectal cancer patients
M van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ...
Cell 161 (4), 933-945, 2015
9562015
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells
W Yang, J Soares, P Greninger, EJ Edelman, H Lightfoot, S Forbes, ...
Nucleic acids research 41 (D1), D955-D961, 2012
8952012
A landscape of pharmacogenomic interactions in cancer
F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...
Cell 166 (3), 740-754, 2016
7452016
Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization
MJ Garnett, S Rana, H Paterson, D Barford, R Marais
Molecular cell 20 (6), 963-969, 2005
3942005
MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling
S Huang, M H÷lzel, T Knijnenburg, A Schlicker, P Roepman, U McDermott, ...
Cell 151 (5), 937-950, 2012
3552012
ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma
SR Knezevich, MJ Garnett, TJ Pysher, JB Beckwith, PE Grundy, ...
Cancer research 58 (22), 5046-5048, 1998
3451998
Human primary liver cancer–derived organoid cultures for disease modeling and drug screening
L Broutier, G Mastrogiovanni, MMA Verstegen, HE Francies, LM Gavarrˇ, ...
Nature medicine 23 (12), 1424, 2017
3252017
Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties
MP Menden, F Iorio, M Garnett, U McDermott, CH Benes, PJ Ballester, ...
PLoS one 8 (4), e61318, 2013
2932013
A biobank of breast cancer explants with preserved intra-tumor heterogeneity to screen anticancer compounds
A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, ...
Cell 167 (1), 260-274. e22, 2016
2462016
UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit
MJ Garnett, J Mansfeld, C Godwin, T Matsusaka, J Wu, P Russell, J Pines, ...
Nature cell biology 11 (11), 1363-1369, 2009
2262009
Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
FM Behan, F Iorio, G Picco, E Gonšalves, CM Beaver, G Migliardi, ...
Nature 568 (7753), 511-516, 2019
2232019
Mutations of C-RAF are rare in human cancer because C-RAF has a low basal kinase activity compared with B-RAF
V Emuss, M Garnett, C Mason, R Marais
Cancer research 65 (21), 9719-9726, 2005
2032005
Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance
M Secrier, X Li, N De Silva, MD Eldridge, G Contino, J Bornschein, ...
Nature genetics 48 (10), 1131-1141, 2016
1802016
Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer
M Michaut, SF Chin, I Majewski, TM Severson, T Bismeijer, L De Koning, ...
Scientific reports 6, 18517, 2016
1232016
The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation
C Tognon, M Garnett, E Kenward, R Kay, K Morrison, PHB Sorensen
Cancer research 61 (24), 8909-8916, 2001
1082001
Targeting the RB-E2F pathway in breast cancer
J Johnson, B Thijssen, U McDermott, M Garnett, LFA Wessels, R Bernards
Oncogene 35 (37), 4829-4835, 2016
1072016
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Articles 1–20