Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13155* | 2021 |
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster I Bjedov, JM Toivonen, F Kerr, C Slack, J Jacobson, A Foley, L Partridge Cell metabolism 11 (1), 35-46, 2010 | 1208 | 2010 |
Stress-induced mutagenesis in bacteria I Bjedov, O Tenaillon, B Gerard, V Souza, E Denamur, M Radman, ... Science 300 (5624), 1404-1409, 2003 | 681 | 2003 |
Autophagy in healthy aging and disease Y Aman, T Schmauck-Medina, M Hansen, RI Morimoto, AK Simon, ... Nature aging 1 (8), 634-650, 2021 | 591 | 2021 |
Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network L Partridge, N Alic, I Bjedov, MDW Piper Experimental gerontology 46 (5), 376-381, 2011 | 336 | 2011 |
Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy R Pryor, P Norvaisas, G Marinos, L Best, LB Thingholm, LM Quintaneiro, ... Cell 178 (6), 1299-1312. e29, 2019 | 196 | 2019 |
Lithium promotes longevity through GSK3/NRF2-dependent hormesis JI Castillo-Quan, L Li, KJ Kinghorn, DK Ivanov, LS Tain, C Slack, F Kerr, ... Cell reports 15 (3), 638-650, 2016 | 180 | 2016 |
A longer and healthier life with TOR down-regulation: genetics and drugs I Bjedov, L Partridge Biochemical Society Transactions 39 (2), 460-465, 2011 | 152 | 2011 |
A Drosophila model of neuronopathic Gaucher disease demonstrates lysosomal-autophagic defects and altered mTOR signalling and is functionally rescued by rapamycin KJ Kinghorn, S Grönke, JI Castillo-Quan, NS Woodling, L Li, E Sirka, ... Journal of Neuroscience 36 (46), 11654-11670, 2016 | 135 | 2016 |
No Influence of Indy on Lifespan in Drosophila after Correction for Genetic and Cytoplasmic Background Effects JM Toivonen, GA Walker, P Martinez-Diaz, I Bjedov, Y Driege, HT Jacobs, ... PLoS genetics 3 (6), e95, 2007 | 116 | 2007 |
Involvement of Escherichia coli DNA Polymerase IV in Tolerance of Cytotoxic Alkylating DNA Lesions in Vivo I Bjedov, CN Dasgupta, D Slade, S Le Blastier, M Selva, I Matic Genetics 176 (3), 1431-1440, 2007 | 96 | 2007 |
A triple drug combination targeting components of the nutrient-sensing network maximizes longevity JI Castillo-Quan, LS Tain, KJ Kinghorn, L Li, S Grönke, Y Hinze, ... Proceedings of the National Academy of Sciences 116 (42), 20817-20819, 2019 | 79 | 2019 |
Increased fidelity of protein synthesis extends lifespan VE Martinez-Miguel, C Lujan, T Espie, D Martinez-Martinez, S Moore, ... Cell metabolism 33 (11), 2288-2300. e12, 2021 | 75 | 2021 |
Molecular mechanisms of lithium action: switching the light on multiple targets for dementia using animal models F Kerr, I Bjedov, O Sofola-Adesakin Frontiers in Molecular Neuroscience 11, 297, 2018 | 72 | 2018 |
The target of rapamycin signalling pathway in ageing and lifespan regulation I Bjedov, C Rallis Genes 11 (9), 1043, 2020 | 71 | 2020 |
Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease O Sofola-Adesakin, JI Castillo-Quan, C Rallis, LS Tain, I Bjedov, I Rogers, ... Frontiers in aging neuroscience 6, 190, 2014 | 69 | 2014 |
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila I Bjedov, HM Cochemé, A Foley, D Wieser, NS Woodling, JI Castillo-Quan, ... PLoS genetics 16 (11), e1009083, 2020 | 51 | 2020 |
Agephagy–adapting autophagy for health during aging ER Stead, JI Castillo-Quan, VEM Miguel, C Lujan, R Ketteler, KJ Kinghorn, ... Frontiers in cell and developmental biology 7, 308, 2019 | 50 | 2019 |
Genetics and pharmacology of longevity: the road to therapeutics for healthy aging JI Castillo-Quan, KJ Kinghorn, I Bjedov Advances in Genetics 90, 1-101, 2015 | 49 | 2015 |
Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control Y Kulaberoglu, K Lin, M Holder, Z Gai, M Gomez, B Assefa Shifa, M Mavis, ... Nature communications 8 (1), 695, 2017 | 38 | 2017 |