Melanie M. Brinkmann
Melanie M. Brinkmann
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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
YM Kim, MM Brinkmann, ME Paquet, HL Ploegh
Nature 452 (7184), 234-238, 2008
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
B Park, MM Brinkmann, E Spooner, CC Lee, YM Kim, HL Ploegh
Nature immunology 9 (12), 1407-1414, 2008
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
MM Brinkmann, E Spooner, K Hoebe, B Beutler, HL Ploegh, YM Kim
The Journal of cell biology 177 (2), 265-275, 2007
Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes
J Henault, J Martinez, JM Riggs, J Tian, P Mehta, L Clarke, M Sasai, ...
Immunity 37 (6), 986-997, 2012
Granulin is a soluble cofactor for toll-like receptor 9 signaling
B Park, L Buti, S Lee, T Matsuwaki, E Spooner, MM Brinkmann, ...
Immunity 34 (4), 505-513, 2011
Kaposi's Sarcoma-Associated Herpesvirus LANA-1 Interacts with the Short Variant of BRD4 and Releases Cells from a BRD4- and BRD2/RING3-Induced G1 Cell …
M Ottinger, T Christalla, K Nathan, MM Brinkmann, A Viejo-Borbolla, ...
Journal of virology 80 (21), 10772-10786, 2006
Activation of mitogen-activated protein kinase and NF-κB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein
MM Brinkmann, M Glenn, L Rainbow, A Kieser, C Henke-Gendo, ...
Journal of virology 77 (17), 9346-9358, 2003
Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS
G Zhang, B Chan, N Samarina, B Abere, M Weidner-Glunde, A Buch, ...
Proceedings of the National Academy of Sciences 113 (8), E1034-E1043, 2016
SARS‐CoV‐2 outbreak investigation in a German meat processing plant
T Günther, M Czech‐Sioli, D Indenbirken, A Robitaille, P Tenhaken, ...
EMBO molecular medicine 12 (12), e13296, 2020
Regulation of intracellular signalling by the terminal membrane proteins of members of the Gammaherpesvirinae
MM Brinkmann, TF Schulz
Journal of general virology 87 (5), 1047-1074, 2006
Murine B cell response to TLR7 ligands depends on an IFN-β feedback loop
NM Green, A Laws, K Kiefer, L Busconi, YM Kim, MM Brinkmann, EH Trail, ...
The Journal of Immunology 183 (3), 1569-1576, 2009
An action plan for pan-European defence against new SARS-CoV-2 variants
V Priesemann, R Balling, MM Brinkmann, S Ciesek, T Czypionka, ...
The Lancet 397 (10273), 469-470, 2021
The chaperone UNC93B1 regulates Toll-like receptor stability independently of endosomal TLR transport
K Pelka, D Bertheloot, E Reimer, K Phulphagar, SV Schmidt, A Christ, ...
Immunity 48 (5), 911-922. e7, 2018
Viral mediated redirection of NEMO/IKKγ to autophagosomes curtails the inflammatory cascade
PM Fliss, TP Jowers, MM Brinkmann, B Holstermann, C Mack, ...
PLoS pathogens 8 (2), e1002517, 2012
Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus
MM Brinkmann, M Pietrek, O Dittrich-Breiholz, M Kracht, TF Schulz
Journal of virology 81 (1), 42-58, 2007
Calling for pan-European commitment for rapid and sustained reduction in SARS-CoV-2 infections
V Priesemann, MM Brinkmann, S Ciesek, S Cuschieri, T Czypionka, ...
The lancet 397 (10269), 92-93, 2021
Age-Dependent Enterocyte Invasion and Microcolony Formation by Salmonella
K Zhang, A Dupont, N Torow, F Gohde, S Leschner, S Lienenklaus, ...
PLoS pathogens 10 (9), e1004385, 2014
The herpesviral antagonist m152 reveals differential activation of STING‐dependent IRF and NF‐κB signaling and STING's dual role during MCMV infection
M Stempel, B Chan, V Juranić Lisnić, A Krmpotić, J Hartung, SR Paludan, ...
The EMBO Journal 38 (5), e100983, 2019
Investigation of a superspreading event preceding the largest meat processing plant-related SARS-Coronavirus 2 outbreak in Germany
T Guenther, M Czech-Sioli, D Indenbirken, A Robitailles, P Tenhaken, ...
Available at SSRN 3654517, 2020
Coevolution pays off: Herpesviruses have the license to escape the DNA sensing pathway
M Stempel, B Chan, MM Brinkmann
Medical Microbiology and Immunology 208 (3-4), 495-512, 2019
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