| In vivo gene editing in dystrophic mouse muscle and muscle stem cells M Tabebordbar, K Zhu, JKW Cheng, WL Chew, JJ Widrick, WX Yan, ... Science 351 (6271), 407-411, 2016 | 1193 | 2016 |
| A multifunctional AAV–CRISPR–Cas9 and its host response WL Chew, M Tabebordbar, JKW Cheng, P Mali, EY Wu, AHM Ng, K Zhu, ... Nature methods 13 (10), 868-874, 2016 | 643 | 2016 |
| Programmable C: G to G: C genome editing with CRISPR-Cas9-directed base excision repair proteins L Chen, JE Park, P Paa, PD Rajakumar, HT Prekop, YT Chew, ... Nature communications 12 (1), 1384, 2021 | 142 | 2021 |
| Immunity to CRISPR Cas9 and Cas12a therapeutics WL Chew Wiley Interdisciplinary Reviews: Systems Biology and Medicine 10 (1), e1408, 2018 | 134 | 2018 |
| TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles J Li, P Kanju, M Patterson, WL Chew, SH Cho, I Gilmour, T Oliver, ... Environmental health perspectives 119 (6), 784-793, 2011 | 130 | 2011 |
| Engineering and optimising deaminase fusions for genome editing L Yang, AW Briggs, WL Chew, P Mali, M Guell, J Aach, DB Goodman, ... Nature Communications 7 (1), 13330, 2016 | 104 | 2016 |
| Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy AM Moreno, N Palmer, F Alemán, G Chen, A Pla, N Jiang, W Leong Chew, ... Nature biomedical engineering 3 (10), 806-816, 2019 | 96 | 2019 |
| Insulin-like growth factor 1 receptor-dependent pathway drives epicardial adipose tissue formation after myocardial injury L Zangi, MS Oliveira, LY Ye, Q Ma, N Sultana, Y Hadas, E Chepurko, ... Circulation 135 (1), 59-72, 2017 | 81 | 2017 |
| Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity CQE Lee, B Kerouanton, S Chothani, S Zhang, Y Chen, CK Mantri, ... Nature communications 12 (1), 2130, 2021 | 66 | 2021 |
| Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy RJ Chai, H Werner, PY Li, YL Lee, KT Nyein, I Solovei, TDA Luu, ... Nature Communications 12 (1), 4722, 2021 | 45 | 2021 |
| Split Cas9 Proteins GM Church, WL Chew US Patent App. 15/541,859, 2018 | 40 | 2018 |
| Translating CRISPR-Cas therapeutics: approaches and challenges LS Tay, N Palmer, R Panwala, WL Chew, P Mali The CRISPR Journal 3 (4), 253-275, 2020 | 28 | 2020 |
| Precise and programmable C: G to G: C base editing in genomic DNA L Chen, JE Park, P Paa, PD Rajakumar, YT Chew, SN Manivannan, ... BioRxiv, 2020.07. 21.213827, 2020 | 17 | 2020 |
| Exploring protein orthogonality in immune space: a case study with AAV and Cas9 orthologs AM Moreno, N Palmer, F Alemán, G Chen, A Pla, WL Chew, M Law, ... BioRxiv, 245985, 2018 | 14 | 2018 |
| Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing N Zeps, T Lysaght, R Chadwick, A Erler, R Foo, S Giordano, P San Lai, ... Stem Cell Reports 16 (7), 1652-1655, 2021 | 7 | 2021 |
| Redox-Responsive Phase-Separating Peptide as a Universal Delivery Vehicle for CRISPR/Cas9 Genome Editing Machinery Y Sun, X Xu, L Chen, WL Chew, Y Ping, A Miserez ACS nano 17 (17), 16597-16606, 2023 | 5 | 2023 |
| RNA-Guided Systems for In Vivo Gene Editing AJ Wagers, M Tabebordbar, WL Chew, GM Church US Patent 20,170,266,320, 2017 | 5 | 2017 |
| RNA-guided systems for in vivo gene editing AJ Wagers, M Tabebordbar, WL Chew, GM Church WO Patent 2016/089,866, 2016 | 5 | 2016 |
| AAV-CRISPR-Cas13 eliminates human enterovirus and prevents death of infected mice CT Keng, T Yogarajah, RCH Lee, IBH Muhammad, BS Chia, ... EBioMedicine 93, 2023 | 4 | 2023 |
| Corrigendum: Engineering and optimising deaminase fusions for genome editing L Yang, AW Briggs, WL Chew, P Mali, M Guell, J Aach, DB Goodman, ... Nature Communications 8, 2017 | 3 | 2017 |
George ChurchHarvard Medical SchoolVerified email at harvard.edu
