Olefin cyclopropanation via carbene transfer catalyzed by engineered cytochrome P450 enzymes PS Coelho, EM Brustad, A Kannan, FH Arnold Science 339 (6117), 307-310, 2013 | 870 | 2013 |
A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo PS Coelho, ZJ Wang, ME Ener, SA Baril, A Kannan, FH Arnold, ... Nature chemical biology 9 (8), 485-487, 2013 | 365 | 2013 |
SCHEMA recombination of a fungal cellulase uncovers a single mutation that contributes markedly to stability P Heinzelman, CD Snow, MA Smith, X Yu, A Kannan, K Boulware, ... Journal of Biological Chemistry 284 (39), 26229-26233, 2009 | 145 | 2009 |
Efficient screening of fungal cellobiohydrolase class I enzymes for thermostabilizing sequence blocks by SCHEMA structure-guided recombination P Heinzelman, R Komor, A Kanaan, P Romero, X Yu, S Mohler, C Snow, ... Protein Engineering, Design & Selection 23 (11), 871-880, 2010 | 122 | 2010 |
High-throughput analysis and protein engineering using microcapillary arrays B Chen, S Lim, A Kannan, SC Alford, F Sunden, D Herschlag, IK Dimov, ... Nature chemical biology 12 (2), 76-81, 2016 | 120 | 2016 |
A conformational ensemble derived using NMR methyl chemical shifts reveals a mechanical clamping transition that gates the binding of the HU protein to DNA A Kannan, C Camilloni, AB Sahakyan, A Cavalli, M Vendruscolo Journal of the American Chemical Society 136 (6), 2204-2207, 2014 | 22 | 2014 |
Selective functionalization of aliphatic amines via myoglobin-catalyzed carbene N–H insertion V Steck, G Sreenilayam, R Fasan Synlett 31 (03), 224-229, 2020 | 20 | 2020 |
Mapping the protein fold universe using the CamTube force field in molecular dynamics simulations P Kukic, A Kannan, MJJ Dijkstra, S Abeln, C Camilloni, M Vendruscolo PLOS Computational Biology 11 (10), e1004435, 2015 | 19 | 2015 |
Micro-screening apparatus, process, and products JR Cochran, TM Baer, B Chen, SC Alford, A Kannan, S Lim, I Dimov US Patent 10,370,653, 2019 | 8 | 2019 |
Corrigendum: A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo. PS Coelho, ZJ Wang, ME Ener, SA Baril, A Kannan, FH Arnold, ... Nature Chemical Biology 10 (2), 2014 | 1 | 2014 |
Micro-screening apparatus, process, and products TM Baer, JR Cochran, B Chen, SC ALFORD, LIM Sungwon, A KANNAN, ... | | 2016 |
Laser extraction from micropore arrays enables high-throughput enzyme engineering A Kannan, B Chen, F Sunden, S Alford, S Lim, I Dimov, D Herschlag, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015 | | 2015 |
Correction: Corrigendum: Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate A Gouzy, G Larrouy-Maumus, TD Wu, A Peixoto, F Levillain, ... Nature Chemical Biology 10 (2), 164-164, 2014 | | 2014 |
Mutated P450 Catalyzed Enantioselective Cyclopropanation B List, JW Lee Synfacts 9 (04), 0442-0442, 2013 | | 2013 |
Predicting function from sequence in venom peptide families A Kannan, G Seshadri | | |
Supplementary Results for PS Coelho, ZJ Wang, ME Ener, SA Baril, AA Kannan, FH Arnold, ... | | |