Christopher Yau
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Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls
N Craddock, ME Hurles, N Cardin, RD Pearson, V Plagnol, S Robson, ...
Nature 464 (7289), 713, 2010
8092010
QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data
S Colella, C Yau, JM Taylor, G Mirza, H Butler, P Clouston, AS Bassett, ...
Nucleic Acids Research 35 (6), 2013-2025, 2007
6222007
ZIFA: Dimensionality reduction for zero-inflated single-cell gene expression analysis
E Pierson, C Yau
Genome biology 16 (1), 1-10, 2015
3672015
On the utility of graphics cards to perform massively parallel simulation of advanced Monte Carlo methods
A Lee, C Yau, MB Giles, A Doucet, CC Holmes
Journal of Computational and Graphical Statistics 19 (4), 769-789, 2010
3232010
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders
JC Taylor, HC Martin, S Lise, J Broxholme, JB Cazier, A Rimmer, ...
Nature genetics 47 (7), 717-726, 2015
2492015
Comparing CNV detection methods for SNP arrays
L Winchester, C Yau, J Ragoussis
Briefings in functional genomics & proteomics 8 (5), 353-366, 2009
2102009
A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data
C Yau, D Mouradov, RN Jorissen, S Colella, G Mirza, G Steers, A Harris, ...
Genome biology 11 (9), R92, 2010
1502010
Bayesian non‐parametric hidden Markov models with applications in genomics
C Yau, O Papaspiliopoulos, GO Roberts, C Holmes
Journal of the Royal Statistical Society: Series B (Statistical Methodology …, 2011
1232011
Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations
D Mouradov, E Domingo, P Gibbs, RN Jorissen, S Li, PY Soo, L Lipton, ...
American Journal of Gastroenterology 108 (11), 1785-1793, 2013
1222013
Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden
JB Cazier, SR Rao, CM McLean, AK Walker, BJ Wright, EEM Jaeger, ...
Nature communications 5 (1), 1-13, 2014
1082014
Presynaptic NMDARs in the hippocampus facilitate transmitter release at theta frequency
L McGuinness, C Taylor, RDT Taylor, C Yau, T Langenhan, ML Hart, ...
Neuron 68 (6), 1109-1127, 2010
1042010
pcaReduce: hierarchical clustering of single cell transcriptional profiles
J Zurauskiene, C Yau
BMC Bioinformatics 17 (140), 2016
972016
GenoSNP: a variational Bayes within-sample SNP genotyping algorithm that does not require a reference population
E Giannoulatou, C Yau, S Colella, J Ragoussis, CC Holmes
Bioinformatics 24 (19), 2209-2214, 2008
752008
Salt-inducible kinase 2 couples ovarian cancer cell metabolism with survival at the adipocyte-rich metastatic niche
F Miranda, D Mannion, S Liu, Y Zheng, LS Mangala, C Redondo, ...
Cancer cell 30 (2), 273-289, 2016
692016
Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia
SJL Knight, C Yau, R Clifford, AT Timbs, ES Akha, HM Dréau, A Burns, ...
Leukemia, 2012
682012
CNV discovery using SNP genotyping arrays
C Yau, CC Holmes
Cytogenetic and genome research 123 (1-4), 307-312, 2008
542008
OncoSNP-SEQ: a statistical approach for the identification of somatic copy number alterations from next-generation sequencing of cancer genomes
C Yau
Bioinformatics 29 (19), 2482-2484, 2013
522013
Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo
GJ Buttrick, LMA Beaumont, J Leitch, C Yau, JR Hughes, JG Wakefield
The Journal of cell biology 180 (3), 537-548, 2008
522008
Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer
R Sahasrabudhe, P Lott, M Bohorquez, T Toal, AP Estrada, JJ Suarez, ...
Gastroenterology 152 (5), 983-986. e6, 2017
492017
Order under uncertainty: robust differential expression analysis using probabilistic models for pseudotime inference
KR Campbell, C Yau
PLoS computational biology 12 (11), e1005212, 2016
492016
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