TNF-α in cancer treatment: molecular insights, antitumor effects, and clinical utility R van Horssen, TLM Ten Hagen, AMM Eggermont The oncologist 11 (4), 397-408, 2006 | 1024 | 2006 |
Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors AA Manzoor, LH Lindner, CD Landon, JY Park, AJ Simnick, MR Dreher, ... Cancer research 72 (21), 5566-5575, 2012 | 488 | 2012 |
Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin RM Schiffelers, GA Koning, TLM ten Hagen, MHAM Fens, AJ Schraa, ... Journal of Controlled Release 91 (1-2), 115-122, 2003 | 429 | 2003 |
Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition PM Krawczyk, B Eppink, J Essers, J Stap, H Rodermond, H Odijk, ... Proceedings of the National Academy of Sciences 108 (24), 9851-9856, 2011 | 378 | 2011 |
Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines A Hollestelle, JHA Nagel, M Smid, S Lam, F Elstrodt, M Wasielewski, ... Breast cancer research and treatment 121, 53-64, 2010 | 344 | 2010 |
Hyperthermia and thermosensitive liposomes for improved delivery of chemotherapeutic drugs to solid tumors GA Koning, AMM Eggermont, LH Lindner, TLM ten Hagen Pharmaceutical research 27, 1750-1754, 2010 | 320 | 2010 |
Current uses of isolated limb perfusion in the clinic and a model system for new strategies AMM Eggermont, JHW de Wilt, TLM ten Hagen The lancet oncology 4 (7), 429-437, 2003 | 315 | 2003 |
Cell membrane modulation as adjuvant in cancer therapy S Zalba, TLM Ten Hagen Cancer treatment reviews 52, 48-57, 2017 | 312 | 2017 |
Macrophages eliminate circulating tumor cells after monoclonal antibody therapy N Gül, L Babes, K Siegmund, R Korthouwer, M Bögels, R Braster, ... The Journal of clinical investigation 124 (2), 812-823, 2014 | 296 | 2014 |
Tumour necrosis factor alpha increases melphalan concentration in tumour tissue after isolated limb perfusion JHW De Wilt, TLM ten Hagen, G De Boeck, ST Van Tiel, EA De Bruijn, ... British journal of cancer 82 (5), 1000-1003, 2000 | 259 | 2000 |
In vivo micro particle image velocimetry measurements of blood-plasma in the embryonic avian heart P Vennemann, KT Kiger, R Lindken, BCW Groenendijk, ... Journal of biomechanics 39 (7), 1191-1200, 2006 | 255 | 2006 |
Triggered content release from optimized stealth thermosensitive liposomes using mild hyperthermia L Li, TLM ten Hagen, D Schipper, TM Wijnberg, GC van Rhoon, ... Journal of Controlled Release 143 (2), 274-279, 2010 | 249 | 2010 |
Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy L Li, TLM ten Hagen, M Hossann, R Süss, GC van Rhoon, ... Journal of Controlled Release 168 (2), 142-150, 2013 | 246 | 2013 |
Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate–containing RGD peptide liposomes inhibits experimental arthritis GA Koning, RM Schiffelers, MHM Wauben, RJ Kok, E Mastrobattista, ... Arthritis & Rheumatism 54 (4), 1198-1208, 2006 | 216 | 2006 |
Improved intratumoral nanoparticle extravasation and penetration by mild hyperthermia L Li, TLM ten Hagen, M Bolkestein, A Gasselhuber, J Yatvin, ... Journal of Controlled Release 167 (2), 130-137, 2013 | 206 | 2013 |
TNF-α augments intratumoural concentrations of doxorubicin in TNF-α-based isolated limb perfusion in rat sarcoma models and enhances anti-tumour effects AH van der Veen, JHW de Wilt, AMM Eggermont, ST van Tiel, ... British journal of cancer 82 (4), 973-980, 2000 | 199 | 2000 |
Tumor necrosis factor α mediates homogeneous distribution of liposomes in murine melanoma that contributes to a better tumor response ALB Seynhaeve, S Hoving, D Schipper, CE Vermeulen, ... Cancer research 67 (19), 9455-9462, 2007 | 188 | 2007 |
Role of CLASP2 in microtubule stabilization and the regulation of persistent motility K Drabek, M van Ham, T Stepanova, K Draegestein, R van Horssen, ... Current Biology 16 (22), 2259-2264, 2006 | 187 | 2006 |
Intact Doxil is taken up intracellularly and released doxorubicin sequesters in the lysosome: evaluated by in vitro/in vivo live cell imaging ALB Seynhaeve, BM Dicheva, S Hoving, GA Koning, TLM Ten Hagen Journal of controlled release 172 (1), 330-340, 2013 | 169 | 2013 |
Hyperthermia and smart drug delivery systems for solid tumor therapy ALB Seynhaeve, M Amin, D Haemmerich, GC Van Rhoon, ... Advanced Drug Delivery Reviews 163, 125-144, 2020 | 167 | 2020 |