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Jeffrey Macdonald
Jeffrey Macdonald
Professor of Biomedical Engineering, University of North Carolina
Bestätigte E-Mail-Adresse bei med.unc.edu - Startseite
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Zitiert von
Zitiert von
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Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ...
Nature medicine 25 (4), 628-640, 2019
5622019
Citrate as an in vivo marker to discriminate prostate cancer from benign prostatic hyperplasia and normal prostate peripheral zone: detection via localized proton spectroscopy
J Kurhanewicz, DB Vigneron, SJ Nelson, H Hricak, JM MacDonald, ...
Urology 45 (3), 459-466, 1995
2941995
In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis
N Grahl, S Puttikamonkul, JM Macdonald, MP Gamcsik, LY Ngo, TM Hohl, ...
PLoS pathogens 7 (7), e1002145, 2011
2382011
Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo
DM Wilson, KR Keshari, PEZ Larson, AP Chen, S Hu, M Van Criekinge, ...
Journal of magnetic resonance 205 (1), 141-147, 2010
2042010
Chemosensitivity of IDH1-mutated gliomas due to an impairment in PARP1-mediated DNA repair
Y Lu, J Kwintkiewicz, Y Liu, K Tech, LN Frady, YT Su, W Bautista, SI Moon, ...
Cancer research 77 (7), 1709-1718, 2017
1972017
Use of pharmaco‐metabonomics for early prediction of acetaminophen‐induced hepatotoxicity in humans
JH Winnike, Z Li, FA Wright, JM Macdonald, TM O'connell, PB Watkins
Clinical Pharmacology & Therapeutics 88 (1), 45-51, 2010
1792010
Differential dynamical effects of macromolecular crowding on an intrinsically disordered protein and a globular protein: implications for in-cell NMR spectroscopy
C Li, LM Charlton, A Lakkavaram, C Seagle, G Wang, GB Young, ...
Journal of the American Chemical Society 130 (20), 6310-6311, 2008
1702008
Citrate alterations in primary and metastatic human prostatic adenocarcinomas: 1H magnetic resonance spectroscopy and biochemical study
J Kurhanewicz, R Dahiya, JM Macdonald, LH Chang, TL James, ...
Magnetic resonance in medicine 29 (2), 149-157, 1993
1491993
Hyperpolarized [2-13C]-Fructose: A Hemiketal DNP Substrate for In Vivo Metabolic Imaging
KR Keshari, DM Wilson, AP Chen, R Bok, PEZ Larson, S Hu, ...
Journal of the American Chemical Society 131 (48), 17591-17596, 2009
1302009
Ribosomal protein–Mdm2–p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation
Y Liu, Y He, A Jin, AP Tikunov, L Zhou, LA Tollini, P Leslie, TH Kim, LO Li, ...
Proceedings of the National Academy of Sciences 111 (23), E2414-E2422, 2014
1252014
Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation
RD Fannin, M Russo, TM O'Connell, K Gerrish, JH Winnike, J Macdonald, ...
Hepatology 51 (1), 227-236, 2010
1122010
Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma
TR Gershon, AJ Crowther, A Tikunov, I Garcia, R Annis, H Yuan, CR Miller, ...
Cancer & metabolism 1, 1-17, 2013
1072013
A sterol-binding protein integrates endosomal lipid metabolism with TOR signaling and nitrogen sensing
CJ Mousley, P Yuan, NA Gaur, KD Trettin, AH Nile, SJ Deminoff, ...
Cell 148 (4), 702-715, 2012
942012
Hyperpolarized 13C spectroscopy and an NMR‐compatible bioreactor system for the investigation of real‐time cellular metabolism
KR Keshari, J Kurhanewicz, RE Jeffries, DM Wilson, BJ Dewar, ...
Magnetic Resonance in Medicine: An Official Journal of the International …, 2010
932010
Closure of VDAC causes oxidative stress and accelerates the Ca2+-induced mitochondrial permeability transition in rat liver mitochondria
A Tikunov, CB Johnson, P Pediaditakis, N Markevich, JM Macdonald, ...
Archives of biochemistry and biophysics 495 (2), 174-181, 2010
912010
Bioreactor design and process for engineering tissue from cells
JM MacDonald, SP Wolfe
US Patent 6,979,308, 2005
902005
Iron control of erythroid development by a novel aconitase-associated regulatory pathway
GC Bullock, LL Delehanty, AL Talbot, SL Gonias, WH Tong, TA Rouault, ...
Blood, The Journal of the American Society of Hematology 116 (1), 97-108, 2010
862010
p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway
DA Franklin, Y He, PL Leslie, AP Tikunov, N Fenger, JM Macdonald, ...
Scientific reports 6 (1), 38067, 2016
842016
Metabolomic Investigations of American Oysters Using 1H-NMR Spectroscopy
AP Tikunov, CB Johnson, H Lee, MK Stoskopf, JM Macdonald
Marine Drugs 8 (10), 2578-2596, 2010
812010
1H NMR-Based Metabolomic Analysis of Liver, Serum, and Brain Following Ethanol Administration in Rats
PC Nicholas, D Kim, FT Crews, JM Macdonald
Chemical Research in Toxicology 21 (2), 408-420, 2008
752008
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