Polo-like kinases and oncogenesis F Eckerdt, J Yuan, K Strebhardt Oncogene 24 (2), 267-276, 2005 | 479 | 2005 |
Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells J Yuan, R Yan, A Krämer, F Eckerdt, M Roller, M Kaufmann, K Strebhardt Oncogene 23 (34), 5843-5852, 2004 | 245 | 2004 |
Cooperative phosphorylation including the activity of polo-like kinase 1 regulates the subcellular localization of cyclin B1 J Yuan, F Eckerdt, J Bereiter-Hahn, E Kurunci-Csacsko, M Kaufmann, ... Oncogene 21 (54), 8282-8292, 2002 | 161 | 2002 |
Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells F Eckerdt, J Yuan, K Saxena, B Martin, S Kappel, C Lindenau, A Kramer, ... Journal of Biological Chemistry 280 (44), 36575-36583, 2005 | 151 | 2005 |
Targeting BET bromodomain proteins in solid tumors V Sahai, AJ Redig, KA Collier, FD Eckerdt, HG Munshi Oncotarget 7 (33), 53997, 2016 | 104 | 2016 |
Polo-like kinase 1: Target and regulator of anaphase-promoting complex/cyclosome–dependent proteolysis F Eckerdt, K Strebhardt Cancer research 66 (14), 6895-6898, 2006 | 104 | 2006 |
Spindle pole regulation by a discrete Eg5-interacting domain in TPX2 F Eckerdt, PA Eyers, AL Lewellyn, C Prigent, JL Maller Current Biology 18 (7), 519-525, 2008 | 83 | 2008 |
Efficient internalization of the polo-box of polo-like kinase 1 fused to an Antennapedia peptide results in inhibition of cancer cell proliferation J Yuan, A Krämer, F Eckerdt, M Kaufmann, K Strebhardt Cancer research 62 (15), 4186-4190, 2002 | 78 | 2002 |
Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes G Pascreau, F Eckerdt, AL Lewellyn, C Prigent, JL Maller Journal of biological chemistry 284 (9), 5497-5505, 2009 | 73 | 2009 |
Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma AD Arslan, A Sassano, D Saleiro, P Lisowski, EM Kosciuczuk, M Fischietti, ... Oncogene 36 (43), 6006-6019, 2017 | 60 | 2017 |
Differential regulation of ZEB1 and EMT by MAPK-interacting protein kinases (MNK) and eIF4E in pancreatic cancer K Kumar, CR Chow, K Ebine, AD Arslan, B Kwok, DJ Bentrem, FD Eckerdt, ... Molecular cancer research 14 (2), 216-227, 2016 | 48 | 2016 |
Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo EM Kosciuczuk, D Saleiro, B Kroczynska, EM Beauchamp, F Eckerdt, ... Blood, The Journal of the American Society of Hematology 128 (3), 410-414, 2016 | 47 | 2016 |
Identification of a polo-like kinase 4-dependent pathway for de novo centriole formation F Eckerdt, TM Yamamoto, AL Lewellyn, JL Maller Current biology 21 (5), 428-432, 2011 | 47 | 2011 |
Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A F Eckerdt, G Pascreau, M Phistry, AL Lewellyn, AA DePaoli-Roach, ... Cell cycle 8 (15), 2413-2419, 2009 | 44 | 2009 |
MNK inhibition disrupts mesenchymal glioma stem cells and prolongs survival in a mouse model of glioblastoma JB Bell, FD Eckerdt, K Alley, LP Magnusson, H Hussain, Y Bi, AD Arslan, ... Molecular Cancer Research 14 (10), 984-993, 2016 | 43 | 2016 |
Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells F Eckerdt, E Beauchamp, J Bell, A Iqbal, B Su, R Fukunaga, RR Lulla, ... Oncotarget 5 (18), 8442, 2014 | 42 | 2014 |
Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding G Pascreau, F Eckerdt, MEA Churchill, JL Maller Proceedings of the National Academy of Sciences 107 (7), 2932-2937, 2010 | 39 | 2010 |
Pituitary tumor-transforming gene expression is a prognostic marker for tumor recurrence in squamous cell carcinoma of the head and neck C Solbach, M Roller, F Eckerdt, S Peters, R Knecht BMC cancer 6, 1-8, 2006 | 39 | 2006 |
HDL nanoparticles targeting sonic hedgehog subtype medulloblastoma JB Bell, JS Rink, F Eckerdt, J Clymer, S Goldman, CS Thaxton, ... Scientific reports 8 (1), 1211, 2018 | 34 | 2018 |
Differential response of glioma stem cells to arsenic trioxide therapy is regulated by MNK1 and mRNA translation JB Bell, F Eckerdt, HD Dhruv, D Finlay, S Peng, S Kim, B Kroczynska, ... Molecular Cancer Research 16 (1), 32-46, 2018 | 33 | 2018 |