Thomas Roper
Thomas Roper
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Enantioselective Mukaiyama-aldol and aldol-dihydropyrone annulation reactions catalyzed by a tryptophan-derived oxazaborolidine
EJ Corey, CL Cywin, TD Roper
Tetrahedron letters 33 (46), 6907-6910, 1992
The origin of greater than 200: 1 enantioselectivity in a catalytic Diels-Alder reaction as revealed by physical and chemical studies
EJ Corey, TP Loh, TD Roper, MD Azimioara, MC Noe
Journal of the American Chemical Society 114 (21), 8290-8292, 1992
7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir
RE Ziegler, BK Desai, JA Jee, BF Gupton, TD Roper, TF Jamison
Angewandte Chemie International Edition 57 (24), 7181-7185, 2018
2-(Purin-9-yl)-tetrahydrofuran-3, 4-diol derivatives
B Cox, SE Keeling, DG Allen, AJ Redgrave, MD Barker, H Hobbs, ...
US Patent 6,426,337, 2002
Catalytic enantioselective Diels-Alder reactions using titanium complexes of cis-N-sulfonyl-2-amino-1-indanols
EJ Corey, TD Roper, K Ishihara, G Sarakinos
Tetrahedron letters 34 (52), 8399-8402, 1993
Synthesis of 4-Fluoro-β-(4-fluorophenyl)-l-phenylalanine by an Asymmetric Phase-Transfer Catalyzed Alkylation:  Synthesis on Scale and Catalyst Stability
DE Patterson, S Xie, LA Jones, MH Osterhout, CG Henry, TD Roper
Organic process research & development 11 (3), 624-627, 2007
Total synthesis of FK-506. Part 2: Completion of the synthesis
RE Ireland, L Liu, TD Roper, JL Gleason
Tetrahedron 53 (39), 13257-13284, 1997
Total synthesis of FK-506. Part 1: Construction of the C16–C34 fragment
RE Ireland, L Liu, TD Roper
Tetrahedron 53 (39), 13221-13256, 1997
Use of a masked aldol unit in the synthesis of the right side of FK-506
RE Ireland, P Wipf, TD Roper
The Journal of Organic Chemistry 55 (8), 2284-2285, 1990
Additive manufacturing of pharmaceuticals for precision medicine applications: A review of the promises and perils in implementation
M Trivedi, J Jee, S Silva, C Blomgren, VM Pontinha, DL Dixon, ...
Additive Manufacturing 23, 319-328, 2018
Efficient Synthesis of an Adenosine A2a Agonist:  Glycosylation of 2-Haloadenines and an N2-Alkyl-6-chloroguanine
JM Caddell, AM Chapman, BE Cooley, BP Downey, MP LeBlanc, ...
The Journal of organic chemistry 69 (9), 3212-3215, 2004
3D printing of metformin HCl PVA tablets by fused deposition modeling: drug loading, tablet design, and dissolution studies
M Ibrahim, M Barnes, R McMillin, DW Cook, S Smith, M Halquist, ...
AAPS PharmSciTech 20 (5), 1-11, 2019
2-(Purin-9-yl)-tetrahydrofuran-3, 4-diol derivatives
B Cox, SE Keeling, DG Allen, AJ Redgrave, MD Barker, H Hobbs, ...
US Patent 6,528,494, 2003
The application of a continuous Grignard reaction in the preparation of fluconazole
S Korwar, S Amir, PN Tosso, BK Desai, CJ Kong, S Fadnis, NS Telang, ...
European Journal of Organic Chemistry 2017 (44), 6495-6498, 2017
Organic Process Res
S Kim, C Wei, S Kaing
Dev 7, 997-1001, 2003
2-(Purin-9-yl)-tetrahydrofuran-3, 4-diol derivatives
DG Allen, C Chan, RPC Cousins, B Cox, JV Geden, H Hobbs, SE Keeling, ...
US Patent 6,495,528, 2002
Continuous flow synthesis of a pharmaceutical intermediate: a computational fluid dynamics approach
CT Armstrong, CQ Pritchard, DW Cook, M Ibrahim, BK Desai, PJ Whitham, ...
Reaction chemistry & engineering 4 (3), 634-642, 2019
Self-Assembly of pH-Labile Polymer Nanoparticles for Paclitaxel Prodrug Delivery: Formulation, Characterization, and Evaluation
SL Levit, NR Gade, TD Roper, H Yang, C Tang
International journal of molecular sciences 21 (23), 9292, 2020
Large-Scale Application of Asymmetric Phase-Transfer Catalysis for Amino Acid Synthesis
DE Patterson, S Xie, LA Jones, MH Osterhout, CG Henry, TD Roper
Asymmetric Catalysis on Industrial Scale, 473-484, 2010
An efficient and scalable synthesis of perfluorinated phosphatidylcholines
TD Roper, PE Friedrich, T Gees, WJ Lackey, C Mader, P Vierling, ...
Organic Process Research & Development 3 (1), 67-70, 1999
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