| Enantioselective Mukaiyama-aldol and aldol-dihydropyrone annulation reactions catalyzed by a tryptophan-derived oxazaborolidine EJ Corey, CL Cywin, TD Roper Tetrahedron letters 33 (46), 6907-6910, 1992 | 309 | 1992 |
| The origin of greater than 200: 1 enantioselectivity in a catalytic Diels-Alder reaction as revealed by physical and chemical studies EJ Corey, TP Loh, TD Roper, MD Azimioara, MC Noe Journal of the American Chemical Society 114 (21), 8290-8292, 1992 | 223 | 1992 |
| 7‐step flow synthesis of the HIV integrase inhibitor dolutegravir RE Ziegler, BK Desai, JA Jee, BF Gupton, TD Roper, TF Jamison Angewandte Chemie 130 (24), 7299-7303, 2018 | 98 | 2018 |
| 3D printing of metformin HCl PVA tablets by fused deposition modeling: drug loading, tablet design, and dissolution studies M Ibrahim, M Barnes, R McMillin, DW Cook, S Smith, M Halquist, ... Aaps Pharmscitech 20, 1-11, 2019 | 82 | 2019 |
| Additive manufacturing of pharmaceuticals for precision medicine applications: A review of the promises and perils in implementation M Trivedi, J Jee, S Silva, C Blomgren, VM Pontinha, DL Dixon, ... Additive Manufacturing 23, 319-328, 2018 | 65 | 2018 |
| Synthesis of 4-Fluoro-β-(4-fluorophenyl)-l-phenylalanine by an Asymmetric Phase-Transfer Catalyzed Alkylation: Synthesis on Scale and Catalyst Stability DE Patterson, S Xie, LA Jones, MH Osterhout, CG Henry, TD Roper Organic process research & development 11 (3), 624-627, 2007 | 60 | 2007 |
| 2-(Purin-9-yl)-tetrahydrofuran-3, 4-diol derivatives B Cox, SE Keeling, DG Allen, AJ Redgrave, MD Barker, H Hobbs, ... US Patent 6,426,337, 2002 | 57 | 2002 |
| Catalytic enantioselective Diels-Alder reactions using titanium complexes of cis-N-sulfonyl-2-amino-1-indanols EJ Corey, TD Roper, K Ishihara, G Sarakinos Tetrahedron letters 34 (52), 8399-8402, 1993 | 56 | 1993 |
| Total synthesis of FK-506. Part 1: Construction of the C16–C34 fragment RE Ireland, L Liu, TD Roper Tetrahedron 53 (39), 13221-13256, 1997 | 42 | 1997 |
| Total synthesis of FK-506. Part 2: Completion of the synthesis RE Ireland, L Liu, TD Roper, JL Gleason Tetrahedron 53 (39), 13257-13284, 1997 | 41 | 1997 |
| Use of a masked aldol unit in the synthesis of the right side of FK-506 RE Ireland, P Wipf, TD Roper The Journal of Organic Chemistry 55 (8), 2284-2285, 1990 | 35 | 1990 |
| PAT implementation on a mobile continuous pharmaceutical manufacturing system: real-time process monitoring with in-line FTIR and Raman spectroscopy Y Miyai, A Formosa, C Armstrong, B Marquardt, L Rogers, T Roper Organic Process Research & Development 25 (12), 2707-2717, 2021 | 30 | 2021 |
| Efficient Synthesis of an Adenosine A2a Agonist: Glycosylation of 2-Haloadenines and an N2-Alkyl-6-chloroguanine JM Caddell, AM Chapman, BE Cooley, BP Downey, MP LeBlanc, ... The Journal of Organic Chemistry 69 (9), 3212-3215, 2004 | 21 | 2004 |
| Continuous flow synthesis of a pharmaceutical intermediate: a computational fluid dynamics approach CT Armstrong, CQ Pritchard, DW Cook, M Ibrahim, BK Desai, PJ Whitham, ... Reaction Chemistry & Engineering 4 (3), 634-642, 2019 | 15 | 2019 |
| The application of a continuous Grignard reaction in the preparation of fluconazole S Korwar, S Amir, PN Tosso, BK Desai, CJ Kong, S Fadnis, NS Telang, ... European Journal of Organic Chemistry 2017 (44), 6495-6498, 2017 | 15 | 2017 |
| Self-assembly of ph-labile polymer nanoparticles for paclitaxel prodrug delivery: Formulation, characterization, and evaluation SL Levit, NR Gade, TD Roper, H Yang, C Tang International Journal of Molecular Sciences 21 (23), 9292, 2020 | 12 | 2020 |
| Encapsulation of a highly hydrophilic drug in polymeric particles: A comparative study of batch and microfluidic processes SS Aboelela, M Ibrahim, AZM Badruddoza, V Tran, JK Ferri, TD Roper International Journal of Pharmaceutics 606, 120906, 2021 | 8 | 2021 |
| CJ Am. Chem. Soc. 1992, 114, 8290.(b) Corey, EJ; Loh, T EJ Corey, TP Loh, TD Roper, MD Azimioara, M Noe PJ Am. Chem. Soc 113, 8966, 1991 | 8 | 1991 |
| 2-(Purin-9-yl)-tetrahydrofuran-3, 4-diol derivatives DG Allen, C Chan, RPC Cousins, B Cox, JV Geden, H Hobbs, SE Keeling, ... US Patent 6,495,528, 2002 | 7 | 2002 |
| Impurity Purging through Systematic Process Development of a Continuous Two-Stage Crystallization D Scott, NEB Briggs, A Formosa, A Burnett, B Desai, G Hammersmith, ... Organic Process Research & Development 27 (1), 148-158, 2023 | 5 | 2023 |
