| Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS CE Hall, Z Yao, M Choi, GE Tyzack, A Serio, R Luisier, J Harley, E Preza, ... Cell reports 19 (9), 1739-1749, 2017 | 179 | 2017 |
| AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons MPM Soutar, L Kempthorne, S Miyakawa, E Annuario, D Melandri, ... Scientific reports 8 (1), 8855, 2018 | 59 | 2018 |
| MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration R Simone, F Javad, W Emmett, OG Wilkins, FL Almeida, ... Nature 594 (7861), 117-123, 2021 | 36 | 2021 |
| Nonsyndromic Parkinson disease in a family with autosomal dominant optic atrophy due to OPA1 mutations DS Lynch, SHY Loh, J Harley, AJ Noyce, LM Martins, NW Wood, ... Neurology: Genetics 3 (5), e188, 2017 | 28 | 2017 |
| Stress-specific spatiotemporal responses of RNA-binding proteins in human stem cell-derived motor neurons J Harley, R Patani International Journal of Molecular Sciences 21 (21), 8346, 2020 | 21 | 2020 |
| The interplay of RNA binding proteins, oxidative stress and mitochondrial dysfunction in ALS J Harley, BE Clarke, R Patani Antioxidants 10 (4), 552, 2021 | 19 | 2021 |
| TDP-43 and FUS mislocalization in VCP mutant motor neurons is reversed by pharmacological inhibition of the VCP D2 ATPase domain J Harley, C Hagemann, A Serio, R Patani Brain Communications 3 (3), fcab166, 2021 | 19 | 2021 |
| FUS is lost from nuclei and gained in neurites of motor neurons in a human stem cell model of VCP-related ALS J Harley, C Hagemann, A Serio, R Patani Brain 143 (12), e103-e103, 2020 | 17 | 2020 |
| Defined Alginate hydrogels support spinal cord organoid derivation, maturation, and modeling of spinal cord diseases WH Chooi, CY Ng, V Ow, J Harley, W Ng, JH Hor, KE Low, B Malleret, ... Advanced Healthcare Materials 12 (9), 2202342, 2023 | 13 | 2023 |
| Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition OJ Ziff, J Harley, Y Wang, J Neeves, G Tyzack, F Ibrahim, M Skehel, ... Neuron 111 (19), 3011-3027. e7, 2023 | 8 | 2023 |
| Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis MP Howe, H Crerar, J Neeves, J Harley, GE Tyzack, P Klein, A Ramos, ... Genome Research 32 (10), 1808-1825, 2022 | 7 | 2022 |
| Image‐based deep learning reveals the responses of human motor neurons to stress and VCP‐related ALS C Verzat, J Harley, R Patani, R Luisier Neuropathology and Applied Neurobiology 48 (2), e12770, 2022 | 4 | 2022 |
| Amplifying the Heat Shock Response Ameliorates ALS and FTD Pathology in Mouse and Human Models M Ahmed, C Spicer, J Harley, JP Taylor, M Hanna, R Patani, ... Molecular Neurobiology 60 (12), 6896-6915, 2023 | 3 | 2023 |
| Telomere shortening induces aging-associated phenotypes in hiPSC-derived neurons and astrocytes J Harley, MM Santosa, CY Ng, OV Grinchuk, JH Hor, Y Liang, VJ Lim, ... Biogerontology, 1-20, 2023 | 2 | 2023 |
| Amplifying the heat shock response ameliorates pathology in mouse and human models of ALS and FTD. M Ahmed, C Spicer, J Harley, N Petersen, P Taylor, T Jensen, M Hanna, ... | 2 | 2021 |
| m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation P Klein, J Harley, H Crook, SE Serna, TI Roumeliotis, JS Choudhary, ... bioRxiv, 2023.09. 12.557394, 2023 | | 2023 |
| Examining responses of RNA binding proteins to ALS and stress in human motor neurons J Harley UCL (University College London), 2021 | | 2021 |
