Matthew Guenther
Matthew Guenther
Syros Pharmaceuticals
Verified email at wi.mit.edu
Title
Cited by
Cited by
Year
Core transcriptional regulatory circuitry in human embryonic stem cells
LA Boyer, TI Lee, MF Cole, SE Johnstone, SS Levine, JP Zucker, ...
cell 122 (6), 947-956, 2005
47012005
Control of developmental regulators by Polycomb in human embryonic stem cells
TI Lee, RG Jenner, LA Boyer, MG Guenther, SS Levine, RM Kumar, ...
Cell 125 (2), 301-313, 2006
23942006
A chromatin landmark and transcription initiation at most promoters in human cells
MG Guenther, SS Levine, LA Boyer, R Jaenisch, RA Young
Cell 130 (1), 77-88, 2007
19492007
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
CJ Phiel, F Zhang, EY Huang, MG Guenther, MA Lazar, PS Klein
Journal of Biological Chemistry 276 (39), 36734-36741, 2001
17752001
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
A Marson, SS Levine, MF Cole, GM Frampton, T Brambrink, S Johnstone, ...
Cell 134 (3), 521-533, 2008
15632008
Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR
W Fischle, F Dequiedt, MJ Hendzel, MG Guenther, MA Lazar, W Voelter, ...
Molecular cell 9 (1), 45-57, 2002
7882002
The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3
MG Guenther, ORR Barak, MA Lazar
Molecular and cellular biology 21 (18), 6091-6101, 2001
6242001
A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness
MG Guenther, WS Lane, W Fischle, E Verdin, MA Lazar, R Shiekhattar
Genes & development 14 (9), 1048-1057, 2000
5242000
Master transcription factors determine cell-type-specific responses to TGF-β signaling
AC Mullen, DA Orlando, JJ Newman, J Lovén, RM Kumar, S Bilodeau, ...
Cell 147 (3), 565-576, 2011
5212011
Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells
MG Guenther, GM Frampton, F Soldner, D Hockemeyer, M Mitalipova, ...
Cell stem cell 7 (2), 249-257, 2010
4582010
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations
CJ Lengner, AA Gimelbrant, JA Erwin, AW Cheng, MG Guenther, ...
Cell 141 (5), 872-883, 2010
3882010
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells
AA Sigova, AC Mullen, B Molinie, S Gupta, DA Orlando, MG Guenther, ...
Proceedings of the National Academy of Sciences 110 (8), 2876-2881, 2013
3782013
Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway
EY Huang, J Zhang, EA Miska, MG Guenther, T Kouzarides, MA Lazar
Genes & development 14 (1), 45-54, 2000
3732000
Global and Hox-specific roles for the MLL1 methyltransferase
MG Guenther, RG Jenner, B Chevalier, T Nakamura, CM Croce, ...
Proceedings of the National Academy of Sciences 102 (24), 8603-8608, 2005
3702005
Proteasomal regulation of nuclear receptor corepressor-mediated repression
J Zhang, MG Guenther, RW Carthew, MA Lazar
Genes & development 12 (12), 1775-1780, 1998
2551998
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia
MG Guenther, LN Lawton, T Rozovskaia, GM Frampton, SS Levine, ...
Genes & development 22 (24), 3403-3408, 2008
2422008
Quantitative ChIP-Seq normalization reveals global modulation of the epigenome
DA Orlando, MW Chen, VE Brown, S Solanki, YJ Choi, ER Olson, CC Fritz, ...
Cell reports 9 (3), 1163-1170, 2014
2322014
Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response
GD Kao, WG McKenna, MG Guenther, RJ Muschel, MA Lazar, TJ Yen
The Journal of cell biology 160 (7), 1017-1027, 2003
2132003
A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation
J Yu, Y Li, T Ishizuka, MG Guenther, MA Lazar
The EMBO journal 22 (13), 3403-3410, 2003
2042003
Assembly of the SMRT–histone deacetylase 3 repression complex requires the TCP-1 ring complex
MG Guenther, J Yu, GD Kao, TJ Yen, MA Lazar
Genes & development 16 (24), 3130-3135, 2002
1402002
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