Enhanced Bruton's tyrosine kinase activity in peripheral blood B lymphocytes from patients with autoimmune disease OBJ Corneth, GMP Verstappen, SMJ Paulissen, MJW de Bruijn, J Rip, ... Arthritis & Rheumatology 69 (6), 1313-1324, 2017 | 110 | 2017 |
The role of Bruton's tyrosine kinase in immune cell signaling and systemic autoimmunity J Rip, EK Van Der Ploeg, RW Hendriks, OBJ Corneth Critical Reviews™ in Immunology 38 (1), 2018 | 97 | 2018 |
Toll-like receptor signaling drives Btk-mediated autoimmune disease J Rip, MJW De Bruijn, MK Appelman, S Pal Singh, RW Hendriks, ... Frontiers in immunology 10, 426047, 2019 | 64 | 2019 |
Enhanced expression of Bruton’s tyrosine kinase in B cells drives systemic autoimmunity by disrupting T cell homeostasis OBJ Corneth, MJW de Bruijn, J Rip, PS Asmawidjaja, LP Kil, RW Hendriks The Journal of Immunology 197 (1), 58-67, 2016 | 50 | 2016 |
Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model S Kumar, MJA Schoonderwoerd, JS Kroonen, IJ de Graaf, M Sluijter, ... Gut 71 (11), 2266-2283, 2022 | 43 | 2022 |
A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection IN Pardieck, TC van der Sluis, ETI van der Gracht, DMB Veerkamp, ... Nature communications 13 (1), 3966, 2022 | 32 | 2022 |
Bruton’s tyrosine kinase inhibition as an emerging therapy in systemic autoimmune disease SFH Neys, J Rip, RW Hendriks, OBJ Corneth Drugs 81 (14), 1605-1626, 2021 | 30 | 2021 |
Phosphoflow protocol for signaling studies in human and murine B cell subpopulations J Rip, MJW de Bruijn, A Kaptein, RW Hendriks, OBJ Corneth The Journal of Immunology 204 (10), 2852-2863, 2020 | 29 | 2020 |
Evidence for enhanced Bruton’s tyrosine kinase activity in transitional and naïve B cells of patients with granulomatosis with polyangiitis A von Borstel, WH Abdulahad, JS Sanders, J Rip, SFH Neys, ... Rheumatology 58 (12), 2230-2239, 2019 | 23 | 2019 |
Distinct and overlapping functions of TEC kinase and BTK in B cell receptor signaling MJW de Bruijn, J Rip, EK Van Der Ploeg, LW Van Greuningen, VTB Ta, ... The Journal of Immunology 198 (8), 3058-3068, 2017 | 22 | 2017 |
Aberrant B cell receptor signaling in naïve B cells from patients with idiopathic pulmonary fibrosis SFH Neys, P Heukels, JAC van Hulst, J Rip, MS Wijsenbeek, ... Cells 10 (6), 1321, 2021 | 15 | 2021 |
Human T-bet+ B cell development is associated with BTK activity and suppressed by evobrutinib L Rijvers, J van Langelaar, L Bogers, MJ Melief, SC Koetzier, KM Blok, ... JCI insight 7 (16), 2022 | 14 | 2022 |
Overexpression of SH2-containing inositol phosphatase contributes to chronic lymphocytic leukemia survival S Pal Singh, MJW de Bruijn, C Velaso Gago da Graça, OBJ Corneth, ... The Journal of Immunology 204 (2), 360-374, 2020 | 6 | 2020 |
Epstein–Barr virus and genetic risk variants as determinants of T-bet+ B cell-driven autoimmune diseases L Bogers, KL Kuiper, J Smolders, J Rip, MM van Luijn Immunology letters 261, 66-74, 2023 | 5 | 2023 |
Bruton's tyrosine kinase inhibition induces rewiring of proximal and distal B‐cell receptor signaling in mice J Rip, MJW de Bruijn, SFH Neys, SP Singh, J Willar, JAC van Hulst, ... European Journal of Immunology 51 (9), 2251-2265, 2021 | 5 | 2021 |
Splenic Architecture and Function Requires Tight Control of Transmembrane TNF Expression KCM Jeucken, MH Kaaij, J Rip, CCN van Rooijen, YY Kan, OBJ Corneth, ... International journal of molecular sciences 23 (4), 2229, 2022 | 3 | 2022 |
Overexpression of transmembrane TNF drives development of ectopic lymphoid structures in the bone marrow and B cell lineage alterations in experimental spondyloarthritis MH Kaaij, J Rip, K Jeucken, YY Kan, CCN van Rooijen, J Saris, D Pots, ... The Journal of Immunology 207 (9), 2337-2346, 2021 | 3 | 2021 |
A versatile protocol to quantify BCR-mediated phosphorylation in human and murine B cell subpopulations J Rip, RW Hendriks, OBJ Corneth Bio-protocol 11 (3), e3902-e3902, 2021 | 3 | 2021 |
Targeting Bruton’s tyrosine kinase expression levels through microRNAs in chronic lymphocytic leukemia treatment SP Singh, J Rip, RW Hendriks Translational Cancer Research 6 (Suppl 3), 2017 | 2 | 2017 |
Differential Runx3, Eomes, and T‐bet expression subdivides MS‐associated CD4+ T cells with brain‐homing capacity C Hoeks, F Puijfelik, SC Koetzier, J Rip, CEA Corsten, AF Wierenga‐Wolf, ... European Journal of Immunology 54 (2), 2350544, 2024 | 1 | 2024 |