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Britton
Britton
IPBS CNRS
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Small-molecule–induced DNA damage identifies alternative DNA structures in human genes
R Rodriguez, KM Miller, JV Forment, CR Bradshaw, M Nikan, S Britton, ...
Nature chemical biology 8 (3), 301-310, 2012
6902012
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining
KM Miller, JV Tjeertes, J Coates, G Legube, SE Polo, S Britton, ...
Nature structural & molecular biology 17 (99), 1144-1151, 2010
6842010
Chemical inhibition of NAT10 corrects defects of laminopathic cells
D Larrieu, S Britton, M Demir, R Rodriguez, SP Jackson
Science 344 (6183), 527-532, 2014
3032014
A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair
S Britton, J Coates, SP Jackson
J Cell Biol 202 (3), 579-595, 2013
2862013
TRF2 and Apollo cooperate with topoisomerase 2α to protect human telomeres from replicative damage
J Ye, C Lenain, S Bauwens, A Rizzo, A Saint-Léger, A Poulet, ...
Cell 142 (2), 230-242, 2010
2002010
DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal
S Britton, E Dernoncourt, C Delteil, C Froment, O Schiltz, B Salles, P Frit, ...
Nucleic acids research, gku601, 2014
1902014
Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks
P Chanut, S Britton, J Coates, SP Jackson, P Calsou
Nature Communications 7, 2016
1532016
Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites
JS Brown, N Lukashchuk, M Sczaniecka-Clift, S Britton, C le Sage, ...
Cell reports 11 (5), 704-714, 2015
1352015
Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks
A Cristini, G Ricci, S Britton, S Salimbeni, SN Huang, J Marinello, ...
Cell reports 28 (12), 3167-3181. e6, 2019
1272019
ATR controls cellular adaptation to hypoxia through positive regulation of hypoxia-inducible factor 1 (HIF-1) expression
F Fallone, S Britton, L Nieto, B Salles, C Muller
Oncogene 32 (37), 4387-4396, 2013
652013
Transcription-associated topoisomerase 2α activity is a major effector of cytotoxicity induced by G-quadruplex ligands
M Bossaert, A Pipier, JF Riou, C Noirot, LT Nguyễn, RF Serre, O Bouchez, ...
Elife 10, e65184, 2021
502021
Cell nonhomologous end joining capacity controls SAF-A phosphorylation by DNA-PK in response to DNA double-strand breaks inducers
S Britton, C Froment, P Frit, B Monsarrat, B Salles, P Calsou
Cell Cycle 8 (22), 3717-3722, 2009
462009
DNA folds threaten genetic stability and can be leveraged for chemotherapy
J Zell, FR Sperti, S Britton, D Monchaud
RSC Chemical Biology, 2020
412020
ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks
S Britton, P Chanut, C Delteil, N Barboule, P Frit, P Calsou
Nucleic Acids Research, 2020
332020
DNA junction ligands trigger DNA damage and are synthetic lethal with DNA repair inhibitors in cancer cells
K Duskova, P Lejault, É Benchimol, R Guillot, S Britton, A Granzhan, ...
Journal of the American Chemical Society, 2019
332019
A novel cytoprotective function for the DNA repair protein Ku in regulating p53 mRNA translation and function
A Lamaa, M Le Bras, N Skuli, S Britton, P Frit, P Calsou, H Prats, ...
EMBO reports 17 (4), 508-518, 2016
302016
ARTEMIS nuclease facilitates apoptotic chromatin cleavage
S Britton, P Frit, D Biard, B Salles, P Calsou
Cancer research 69 (20), 8120-8126, 2009
302009
Identification of three-way DNA junction ligands through screening of chemical libraries and validation by complementary in vitro assays
K Duskova, J Lamarche, S Amor, C Caron, N Queyriaux, M Gaschard, ...
Journal of medicinal chemistry, 2019
282019
BRCA1 prevents R-loop-associated centromeric instability
C Racca, S Britton, S Hédouin, C Francastel, P Calsou, F Larminat
Cell Death & Disease 12 (10), 1-11, 2021
272021
Phosphorylation of SAF-A/hnRNP-U serine 59 by Polo-like kinase 1 is required for mitosis
P Douglas, R Ye, N Morrice, S Britton, L Trinkle-Mulcahy, SP Lees-Miller
Molecular and cellular biology 35 (15), 2699-2713, 2015
252015
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