Follow
Zara Sands
Zara Sands
UCB BioPharma
Verified email at ucb.com
Title
Cited by
Cited by
Year
An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1
IS Ramsey, Y Mokrab, I Carvacho, ZA Sands, MSP Sansom, DE Clapham
Nature structural & molecular biology 17 (7), 869-875, 2010
1752010
Design, Synthesis, and Biophysical and Biological Evaluation of a Series of Pyrrolobenzodiazepine−Poly(N-methylpyrrole) Conjugates
G Wells, CRH Martin, PW Howard, ZA Sands, CA Laughton, A Tiberghien, ...
Journal of medicinal chemistry 49 (18), 5442-5461, 2006
1702006
Synaptic vesicle glycoprotein 2A ligands in the treatment of epilepsy and beyond
W Löscher, M Gillard, ZA Sands, RM Kaminski, H Klitgaard
CNS drugs 30, 1055-1077, 2016
1612016
Crystal structure of the adenosine A2A receptor bound to an antagonist reveals a potential allosteric pocket
B Sun, P Bachhawat, MLH Chu, M Wood, T Ceska, ZA Sands, J Mercier, ...
Proceedings of the National Academy of Sciences 114 (8), 2066-2071, 2017
1382017
Binding mode and structure–activity relationships around direct inhibitors of the Nrf2–Keap1 complex
E Jnoff, C Albrecht, JJ Barker, O Barker, E Beaumont, S Bromidge, ...
ChemMedChem 9 (4), 699-705, 2014
1382014
How does a voltage sensor interact with a lipid bilayer? Simulations of a potassium channel domain
ZA Sands, MSP Sansom
Structure 15 (2), 235-244, 2007
1122007
Molecular dynamics simulations of duplex stretching reveal the importance of entropy in determining the biomechanical properties of DNA
SA Harris, ZA Sands, CA Laughton
Biophysical journal 88 (3), 1684-1691, 2005
1112005
Voltage-gated ion channels
Z Sands, A Grottesi, MSP Sansom
Current Biology 15 (2), R44-R47, 2005
872005
Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations
PJ Stansfeld, A Grottesi, ZA Sands, MSP Sansom, P Gedeck, M Gosling, ...
Biochemistry 47 (28), 7414-7422, 2008
692008
GRIN2B gain of function mutations are sensitive to radiprodil, a negative allosteric modulator of GluN2B-containing NMDA receptors
B Mullier, C Wolff, ZA Sands, P Ghisdal, P Muglia, RM Kaminski, ...
Neuropharmacology 123, 322-331, 2017
552017
Molecular simulations and lipid–protein interactions: potassium channels and other membrane proteins
MSP Sansom, PJ Bond, SS Deol, A Grottesi, S Haider, ZA Sands
Biochemical Society Transactions 33 (5), 916-920, 2005
532005
Detergent-free extraction of a functional low-expressing GPCR from a human cell line
JFB Juarez, JC Muñoz-García, RI Dos Reis, A Henry, D McMillan, M Kriek, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (3), 183152, 2020
462020
Alchembed: a computational method for incorporating multiple proteins into complex lipid geometries
E Jefferys, ZA Sands, J Shi, MSP Sansom, PW Fowler
Journal of Chemical Theory and Computation 11 (6), 2743-2754, 2015
462015
SGTx1, a Kv channel gating-modifier toxin, binds to the interfacial region of lipid bilayers
CL Wee, D Bemporad, ZA Sands, D Gavaghan, MSP Sansom
Biophysical journal 92 (1), L07-L09, 2007
432007
Vstx1, a modifier of Kv channel gating, localizes to the interfacial region of lipid bilayers
D Bemporad, ZA Sands, CL Wee, A Grottesi, MSP Sansom
Biochemistry 45 (39), 11844-11855, 2006
432006
Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist
B Sun, D Feng, MLH Chu, I Fish, S Lovera, ZA Sands, S Kelm, A Valade, ...
Nature communications 12 (1), 3305, 2021
412021
The intrinsic flexibility of the Kv voltage sensor and its implications for channel gating
ZA Sands, A Grottesi, MSP Sansom
Biophysical journal 90 (5), 1598-1606, 2006
412006
A numbering system for MFS transporter proteins
J Lee, ZA Sands, PC Biggin
Frontiers in molecular biosciences 3, 21, 2016
402016
Exploring the interaction of SV2A with racetams using homology modelling, molecular dynamics and site-directed mutagenesis
J Lee, V Daniels, ZA Sands, F Lebon, J Shi, PC Biggin
PLoS One 10 (2), e0116589, 2015
302015
Further evidence for a differential interaction of brivaracetam and levetiracetam with the synaptic vesicle 2A protein
MD Wood, ZA Sands, C Vandenplas, M Gillard
Epilepsia 59 (9), e147-e151, 2018
292018
The system can't perform the operation now. Try again later.
Articles 1–20