| The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ... Nature 483 (7391), 603-607, 2012 | 7704 | 2012 |
| Comprehensive genomic characterization defines human glioblastoma genes and core pathways Cancer Genome Atlas Research Network Tissue source sites: Duke University ... Nature 455 (7216), 1061-1068, 2008 | 7313 | 2008 |
| Mutational heterogeneity in cancer and the search for new cancer-associated genes MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ... Nature 499 (7457), 214-218, 2013 | 5736 | 2013 |
| The landscape of somatic copy-number alteration across human cancers R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ... Nature 463 (7283), 899-905, 2010 | 4188 | 2010 |
| Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ... Science 352 (6282), 189-196, 2016 | 3815 | 2016 |
| Integrative clinical genomics of advanced prostate cancer D Robinson, EM Van Allen, YM Wu, N Schultz, RJ Lonigro, JM Mosquera, ... Cell 161 (5), 1215-1228, 2015 | 3609 | 2015 |
| Discovery and saturation analysis of cancer genes across 21 tumour types MS Lawrence, P Stojanov, CH Mermel, JT Robinson, LA Garraway, ... Nature 505 (7484), 495-501, 2014 | 3184 | 2014 |
| Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ... Science 351 (6280), 1463-1469, 2016 | 2952 | 2016 |
| A landscape of driver mutations in melanoma E Hodis, IR Watson, GV Kryukov, ST Arold, M Imielinski, JP Theurillat, ... Cell 150 (2), 251-263, 2012 | 2919 | 2012 |
| Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden ZR Chalmers, CF Connelly, D Fabrizio, L Gay, SM Ali, R Ennis, A Schrock, ... Genome medicine 9, 1-14, 2017 | 2900 | 2017 |
| The mutational landscape of head and neck squamous cell carcinoma N Stransky, AM Egloff, AD Tward, AD Kostic, K Cibulskis, A Sivachenko, ... science 333 (6046), 1157-1160, 2011 | 2785 | 2011 |
| Genomic correlates of response to CTLA-4 blockade in metastatic melanoma EM Van Allen, D Miao, B Schilling, SA Shukla, C Blank, L Zimmer, ... Science 350 (6257), 207-211, 2015 | 2693 | 2015 |
| Genomic classification of cutaneous melanoma R Akbani, KC Akdemir, BA Aksoy, M Albert, A Ally, SB Amin, H Arachchi, ... Cell 161 (7), 1681-1696, 2015 | 2652 | 2015 |
| Integrated genomic characterization of papillary thyroid carcinoma N Agrawal, R Akbani, BA Aksoy, A Ally, H Arachchi, SL Asa, JT Auman, ... Cell 159 (3), 676-690, 2014 | 2482 | 2014 |
| Next-generation characterization of the cancer cell line encyclopedia M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ... Nature 569 (7757), 503-508, 2019 | 2364 | 2019 |
| Highly recurrent TERT promoter mutations in human melanoma FW Huang, E Hodis, MJ Xu, GV Kryukov, L Chin, LA Garraway Science 339 (6122), 957-959, 2013 | 2105 | 2013 |
| Defining a cancer dependency map A Tsherniak, F Vazquez, PG Montgomery, BA Weir, G Kryukov, ... Cell 170 (3), 564-576. e16, 2017 | 2000 | 2017 |
| Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing M Imielinski, AH Berger, PS Hammerman, B Hernandez, TJ Pugh, ... Cell 150 (6), 1107-1120, 2012 | 1974 | 2012 |
| Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma LA Garraway, HR Widlund, MA Rubin, G Getz, AJ Berger, S Ramaswamy, ... Nature 436 (7047), 117-122, 2005 | 1783 | 2005 |
| Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer CE Barbieri, SC Baca, MS Lawrence, F Demichelis, M Blattner, ... Nature genetics 44 (6), 685-689, 2012 | 1726 | 2012 |
