|Multiple high-throughput analyses monitor the response of E. coli to perturbations|
N Ishii, K Nakahigashi, T Baba, M Robert, T Soga, A Kanai, T Hirasawa, ...
Science 316 (5824), 593-597, 2007
|Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae|
K Yoshikawa, T Tanaka, C Furusawa, K Nagahisa, T Hirasawa, H Shimizu
FEMS yeast research 9 (1), 32-44, 2009
|Identification of target genes conferring ethanol stress tolerance to Saccharomyces cerevisiae based on DNA microarray data analysis|
T Hirasawa, K Yoshikawa, Y Nakakura, K Nagahisa, C Furusawa, ...
Journal of biotechnology 131 (1), 34-44, 2007
|Comprehensive phenotypic analysis of single‐gene deletion and overexpression strains of Saccharomyces cerevisiae|
K Yoshikawa, T Tanaka, Y Ida, C Furusawa, T Hirasawa, H Shimizu
Yeast 28 (5), 349-361, 2011
|Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum|
Y Shinfuku, N Sorpitiporn, M Sono, C Furusawa, T Hirasawa, H Shimizu
Microbial cell factories 8 (1), 43, 2009
|Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress|
T Horinouchi, K Tamaoka, C Furusawa, N Ono, S Suzuki, T Hirasawa, ...
BMC genomics 11 (1), 579, 2010
|13C‐metabolic flux analysis for batch culture of Escherichia coli and its pyk and pgi gene knockout mutants based on mass isotopomer distribution of intracellular …|
Y Toya, N Ishii, K Nakahigashi, T Hirasawa, T Soga, M Tomita, K Shimizu
Biotechnology progress 26 (4), 975-992, 2010
|Differential importance of trehalose accumulation in Saccharomyces cerevisiae in response to various environmental stresses|
SA Mahmud, T Hirasawa, H Shimizu
Journal of Bioscience and Bioengineering 109 (3), 262-266, 2010
|Adaptation of Saccharomyces cerevisiae cells to high ethanol concentration and changes in fatty acid composition of membrane and cell size|
TN Dinh, K Nagahisa, T Hirasawa, C Furusawa, H Shimizu
PLoS One 3 (7), e2623, 2008
|Comparative analysis of transcriptional responses to saline stress in the laboratory and brewing strains of Saccharomyces cerevisiae with DNA microarray|
T Hirasawa, Y Nakakura, K Yoshikawa, K Ashitani, K Nagahisa, ...
Applied Microbiology and Biotechnology 70 (3), 346-357, 2006
|Direct measurement of isotopomer of intracellular metabolites using capillary electrophoresis time-of-flight mass spectrometry for efficient metabolic flux analysis|
Y Toya, N Ishii, T Hirasawa, M Naba, K Hirai, K Sugawara, S Igarashi, ...
Journal of chromatography A 1159 (1-2), 134-141, 2007
|Reconstruction and verification of a genome-scale metabolic model for Synechocystis sp. PCC6803|
K Yoshikawa, Y Kojima, T Nakajima, C Furusawa, T Hirasawa, H Shimizu
Applied microbiology and biotechnology 92 (2), 347, 2011
|Distinct roles of two anaplerotic pathways in glutamate production induced by biotin limitation in Corynebacterium glutamicum|
H Sato, K Orishimo, T Shirai, T Hirasawa, K Nagahisa, H Shimizu, ...
Journal of bioscience and bioengineering 106 (1), 51-58, 2008
|Effect of trehalose accumulation on response to saline stress in Saccharomyces cerevisiae|
SA Mahmud, K Nagahisa, T Hirasawa, K Yoshikawa, K Ashitani, ...
Yeast 26 (1), 17-30, 2009
|Effect of odhA overexpression and odhA antisense RNA expression on Tween-40-triggered glutamate production by Corynebacterium glutamicum|
J Kim, T Hirasawa, Y Sato, K Nagahisa, C Furusawa, H Shimizu
Applied microbiology and biotechnology 81 (6), 1097, 2009
|A mutation in the Corynebacterium glutamicum ltsA gene causes susceptibility to lysozyme, temperature-sensitive growth, and L-glutamate production|
T Hirasawa, M Wachi, K Nagai
Journal of bacteriology 182 (10), 2696-2701, 2000
|Integrated Metabolic Flux and Omics Analysis of Synechocystis sp. PCC 6803 under Mixotrophic and Photoheterotrophic Conditions|
T Nakajima, S Kajihata, K Yoshikawa, F Matsuda, C Furusawa, ...
Plant and Cell Physiology 55 (9), 1605-1612, 2014
|Production of glutamate and glutamate-related amino acids: molecular mechanism analysis and metabolic engineering|
H Shimizu, T Hirasawa
Amino acid biosynthesis~ pathways, regulation and metabolic engineering, 1-38, 2006
|Recent advances in amino acid production by microbial cells|
T Hirasawa, H Shimizu
Current opinion in biotechnology 42, 133-146, 2016
|Requirement of de novo synthesis of the OdhI protein in penicillin-induced glutamate production by Corynebacterium glutamicum|
J Kim, H Fukuda, T Hirasawa, K Nagahisa, K Nagai, M Wachi, H Shimizu
Applied microbiology and biotechnology 86 (3), 911-920, 2010