Justin Crocker
Justin Crocker
Group Leader, EMBL Heidelberg
Verified email at - Homepage
Cited by
Cited by
Low affinity binding site clusters confer hox specificity and regulatory robustness
J Crocker, N Abe, L Rinaldi, AP McGregor, N Frankel, S Wang, ...
Cell 160 (1), 191-203, 2015
The Soft Touch: Low-Affinity Transcription Factor Binding Sites in Development and Evolution
J Crocker, EPB Noon, DL Stern
Current topics in developmental biology 117, 455-469, 2016
Nuclear microenvironments modulate transcription from low-affinity enhancers
A Tsai, AK Muthusamy, MRP Alves, LD Lavis, RH Singer, DL Stern, ...
Elife 6, e28975, 2017
Evolution acts on enhancer organization to fine-tune gradient threshold readouts
J Crocker, Y Tamori, A Erives
PLoS biology 6 (11), e263, 2008
Accurate and sensitive quantification of protein-DNA binding affinity
C Rastogi, HT Rube, JF Kribelbauer, J Crocker, RE Loker, GD Martini, ...
Proceedings of the National Academy of Sciences 115 (16), E3692-E3701, 2018
TALE-mediated modulation of transcriptional enhancers in vivo
J Crocker, DL Stern
Nature methods, 2013
Multi-enhancer transcriptional hubs confer phenotypic robustness
A Tsai, MRP Alves, J Crocker
eLife, 8:e45325, 2019
Genetic and Transgenic Reagents for Drosophila simulans, D. mauritiana, D. yakuba, D. santomea, and D. virilis
DL Stern, J Crocker, Y Ding, N Frankel, G Kappes, E Kim, R Kuzmickas, ...
G3: Genes, Genomes, Genetics 7 (4), 1339-1347, 2017
Dense and pleiotropic regulatory information in a developmental enhancer
T Fuqua, J Jordan, ME van Breugel, A Halavatyi, C Tischer, P Polidoro, ...
Nature 587 (7833), 235-239, 2020
Dynamic evolution of precise regulatory encodings creates the clustered site signature of enhancers
J Crocker, N Potter, A Erives
Nature communications 1 (1), 99, 2010
A fully synthetic transcriptional platform for a multicellular eukaryote
J Crocker, A Tsai, DL Stern
Cell Reports 18 (1), 287-296, 2017
Quantitatively predictable control of Drosophila transcriptional enhancers in vivo with engineered transcription factors
J Crocker, GR Ilsley, DL Stern
Nature genetics 48 (3), 292-298, 2016
Using synthetic biology to study gene regulatory evolution
J Crocker, GR Ilsley
Current opinion in genetics & development 47, 91-101, 2017
A Schnurri/Mad/Medea complex attenuates the Dorsal-Twist gradient readout at vnd
J Crocker, A Erives
Developmental biology, 2013
A Closer Look at the eve Stripe 2 Enhancers of Drosophila and Themira
J Crocker, A Erives
PLoS genetics 4 (11), e1000276, 2008
Enhancer architecture and chromatin accessibility constrain phenotypic space during Drosophila development
R Galupa, G Alvarez-Canales, NO Borst, T Fuqua, L Gandara, N Misunou, ...
Developmental Cell 58 (1), 51-62. e4, 2023
Functional regulatory evolution outside of the minimal even-skipped stripe 2 enhancer
J Crocker, DL Stern
Development 144 (17), 3095-3101, 2017
Robust and efficient gene regulation through localized nuclear microenvironments
A Tsai, R Galupa, J Crocker
Development 147 (19), dev161430, 2020
An open-source semi-automated robotics pipeline for embryo immunohistochemistry
T Fuqua, J Jordan, A Halavatyi, C Tischer, K Richter, J Crocker
Scientific Reports 11 (1), 10314, 2021
Developmental phenomics suggests that H3K4 monomethylation confers multi-level phenotypic robustness
L Gandara, A Tsai, M Ekelöf, R Galupa, EPB Noon, T Alexandrov, ...
Cell Reports 41 (11), 2022
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